SKT5/YBL061C Summary Help

SKT5 BASIC INFORMATION

Standard Name SKT5
Systematic Name YBL061C
Alias CAL2 , CHS4 , CSD4
Feature Type ORF, Verified
Description Activator of Chs3p (chitin synthase III), recruits Chs3p to the bud neck via interaction with Bni4p; has similarity to Shc1p, which activates Chs3p during sporulation (1, 2, 3, 4)
GO Annotations All SKT5 GO evidence and references
    View Computational GO annotations for SKT5
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All SKT5 Phenotype details and references
Classical genetics
reduction of function
Large-scale survey
null
Interactions SKT5 All interactions details and references
143 total interaction(s) for 78 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 11
  • Biochemical Activity: 8
  • Two-hybrid: 6
Genetic Interactions
  • Dosage Lethality: 2
  • Dosage Rescue: 3
  • Synthetic Growth Defect: 4
  • Synthetic Lethality: 109
Sequence Information
ChrII:107408 to 105318 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2004-07-16 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..2091 107408..105318 2004-07-16 1997-01-28
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000000157

SKT5 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
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  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for SKT5

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for SKT5]

1) Ono N, et al.  (2000) The yeast Chs4 protein stimulates the trypsin-sensitive activity of chitin synthase 3 through an apparent protein-protein interaction. Microbiology 146 ( Pt 2):385-91
2) Trilla JA, et al.  (1997) Characterization of CHS4 (CAL2), a gene of Saccharomyces cerevisiae involved in chitin biosynthesis and allelic to SKT5 and CSD4. Yeast 13(9):795-807
3) Sanz M, et al.  (2002) Control of chitin synthesis through Shc1p, a functional homologue of Chs4p specifically induced during sporulation. Mol Microbiol 43(5):1183-95
4) Kozubowski L, et al.  (2003) A Bni4-Glc7 phosphatase complex that recruits chitin synthase to the site of bud emergence. Mol Biol Cell 14(1):26-39