SEC17/YBL050W Summary Help

SEC17 BASIC INFORMATION

Standard Name SEC17 1
Systematic Name YBL050W
Alias RNS3 2
Feature Type ORF, Verified
Description Peripheral membrane protein required for vesicular transport between ER and Golgi and for the 'priming' step in homotypic vacuole fusion, part of the cis-SNARE complex; has similarity to alpha-SNAP (3)
Name Description SECretory 4
GO Annotations All SEC17 GO evidence and references
    View Computational GO annotations for SEC17
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All SEC17 Phenotype details and references
Classical genetics
conditional
null
overexpression
repressible
Large-scale survey
null
overexpression
repressible
Interactions SEC17 All interactions details and references
70 total interaction(s) for 31 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 42
  • Co-fractionation: 6
  • Co-purification: 4
  • Reconstituted Complex: 6
Genetic Interactions
  • Dosage Lethality: 1
  • Dosage Rescue: 1
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 4
Sequence Information
ChrII:125128 to 126122 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2004-07-16 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..30 125128..125157 2004-07-16 1997-01-28
Intron 31..146 125158..125273 2004-07-16 1997-01-28
CDS 147..995 125274..126122 2004-07-16 1997-01-28
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000000146

SEC17 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Literature
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  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for SEC17

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for SEC17]

1) Novick P, et al.  (1980) Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway. Cell 21(1):205-15
2) Ishikawa T, et al.  (2005) Isolation of Saccharomyces cerevisiae RNase T1 hypersensitive (rns) mutants and genetic analysis of the RNS1/DSL1 gene. J Gen Appl Microbiol 51(1):73-82
3) Wickner W and Haas A  (2000) Yeast homotypic vacuole fusion: a window on organelle trafficking mechanisms. Annu Rev Biochem 69:247-75
4) Novick P and Schekman R  (1979) Secretion and cell-surface growth are blocked in a temperature-sensitive mutant of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 76(4):1858-62