MRPL16/YBL038W Summary Help

Standard Name MRPL16 1
Systematic Name YBL038W
Alias RML16 2
Feature Type ORF, Verified
Description Mitochondrial ribosomal protein of the large subunit; homologous to bacterial L16 ribosomal protein; synthetically lethal with hac1 mutant suggesting a role in the maturation of secretory proteins (1, 2, 3, 4)
Name Description Mitochondrial Ribosomal Protein, Large subunit 1
Gene Product Alias YmL47 1
Chromosomal Location
ChrII:146187 to 146885 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All MRPL16 GO evidence and references
  View Computational GO annotations for MRPL16
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 3 genes
Resources
Classical genetics
null
Large-scale survey
null
unspecified
Resources
82 total interaction(s) for 46 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 74
  • Affinity Capture-RNA: 4

Genetic Interactions
  • Dosage Lethality: 1
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 232
Molecular Weight (Da) 26,518
Isoelectric Point (pI) 11.12
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrII:146187 to 146885 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..699 146187..146885 2011-02-03 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000134
References cited on this page View Complete Literature Guide for MRPL16
1) Kitakawa M, et al.  (1997) Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae. Eur J Biochem 245(2):449-56
2) Pan C and Mason TL  (1995) Identification of the yeast nuclear gene for the mitochondrial homologue of bacterial ribosomal protein L16. Nucleic Acids Res 23(18):3673-7
3) Graack HR and Wittmann-Liebold B  (1998) Mitochondrial ribosomal proteins (MRPs) of yeast. Biochem J 329 ( Pt 3)():433-48
4) Copic A, et al.  (2009) Genomewide analysis reveals novel pathways affecting endoplasmic reticulum homeostasis, protein modification and quality control. Genetics 182(3):757-69