RRN10/YBL025W Summary Help

Standard Name RRN10 1
Systematic Name YBL025W
Feature Type ORF, Verified
Description Protein involved in promoting high level transcription of rDNA; subunit of UAF (upstream activation factor) for RNA polymerase I (1, 2, 3)
Name Description Regulation of RNA polymerase I 1
Chromosomal Location
ChrII:171481 to 171918 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All RRN10 GO evidence and references
  View Computational GO annotations for RRN10
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 2 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
32 total interaction(s) for 27 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 10
  • Affinity Capture-RNA: 4
  • Affinity Capture-Western: 1
  • Co-purification: 1
  • Two-hybrid: 5

Genetic Interactions
  • Dosage Rescue: 4
  • Negative Genetic: 2
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 145
Molecular Weight (Da) 16,505
Isoelectric Point (pI) 4.95
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrII:171481 to 171918 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..438 171481..171918 2011-02-03 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000121
References cited on this page View Complete Literature Guide for RRN10
1) Keys DA, et al.  (1996) Multiprotein transcription factor UAF interacts with the upstream element of the yeast RNA polymerase I promoter and forms a stable preinitiation complex. Genes Dev 10(7):887-903
2) Steffan JS, et al.  (1996) The role of TBP in rDNA transcription by RNA polymerase I in Saccharomyces cerevisiae: TBP is required for upstream activation factor-dependent recruitment of core factor. Genes Dev 10(20):2551-63
3) Keener J, et al.  (1998) Reconstitution of yeast RNA polymerase I transcription in vitro from purified components. TATA-binding protein is not required for basal transcription. J Biol Chem 273(50):33795-802