SCT1/YBL011W Summary Help

Standard Name SCT1 1
Systematic Name YBL011W
Alias GAT2 2
Feature Type ORF, Verified
Description Glycerol 3-phosphate/dihydroxyacetone phosphate dual substrate-specific sn-1 acyltransferase of the glycerolipid biosynthesis pathway, prefers 16-carbon fatty acids, similar to Gpt2p, gene is constitutively transcribed (1, 2)
Name Description Suppressor of Choline-Transport mutants 1
Chromosomal Location
ChrII:203538 to 205817 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All SCT1 GO evidence and references
  View Computational GO annotations for SCT1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Pathways
Classical genetics
null
Large-scale survey
null
Resources
98 total interaction(s) for 73 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-Western: 1
  • Biochemical Activity: 16
  • PCA: 1
  • Reconstituted Complex: 3
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Rescue: 6
  • Negative Genetic: 45
  • Phenotypic Enhancement: 1
  • Phenotypic Suppression: 2
  • Positive Genetic: 14
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 2
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrII:203538 to 205817 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2280 203538..205817 2011-02-03 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000107
References cited on this page View Complete Literature Guide for SCT1
1) Matsushita M and Nikawa J  (1995) Isolation and characterization of a SCT1 gene which can suppress a choline-transport mutant of Saccharomyces cerevisiae. J Biochem 117(2):447-51
2) Zheng Z and Zou J  (2001) The initial step of the glycerolipid pathway: identification of glycerol 3-phosphate/dihydroxyacetone phosphate dual substrate acyltransferases in Saccharomyces cerevisiae. J Biol Chem 276(45):41710-6