IMD1/YAR073W Summary Help

Standard Name IMD1 1
Systematic Name YAR073W
Feature Type ORF, Dubious
Description Nonfunctional protein with homology to IMP dehydrogenase; blocked reading frame, located close to the telomere; not expressed at detectable levels; YAR073W and YAR075W comprise a continuous reading frame in most strains of S. cerevisiae; YAR073W/YAR075W together have a paralog, IMD2, that arose from a segmental duplication (2, 3)
Name Description IMP Dehydrogenase 1
Chromosomal Location
ChrI:227742 to 228953 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All IMD1 GO evidence and references
  View Computational GO annotations for IMD1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 4 genes
Resources
Classical genetics
null
Resources
Expression Summary
histogram
Resources
Length (a.a.) 403
Molecular Weight (Da) 44,386
Isoelectric Point (pI) 8.2
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrI:227742 to 228953 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1212 227742..228953 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000095
References cited on this page View Complete Literature Guide for IMD1
1) Escobar-Henriques M and Daignan-Fornier B  (2001) Transcriptional regulation of the yeast gmp synthesis pathway by its end products. J Biol Chem 276(2):1523-30
2) Hyle JW, et al.  (2003) Functional distinctions between IMP dehydrogenase genes in providing mycophenolate resistance and guanine prototrophy to yeast. J Biol Chem 278(31):28470-8
3) Katju V, et al.  (2009) Variation in gene duplicates with low synonymous divergence in Saccharomyces cerevisiae relative to Caenorhabditis elegans. Genome Biol 10(7):R75