YAR062W Summary Help

Systematic Name YAR062W
Feature Type pseudogene
Description Pseudogenic fragment with similarity to flocculins; YAR062W has a paralog, YHR213W, that arose from a segmental duplication (1, 2 and see Summary Paragraph)
Chromosomal Location
ChrI:218549 to 219145 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All YAR062W GO evidence and references
  View Computational GO annotations for YAR062W
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
3 total interaction(s) for 3 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 198
Molecular Weight (Da) 21,145
Isoelectric Point (pI) 3.8
Localization
Phosphorylation PhosphoGRID
Structure
Homologs
sequence information
ChrI:218549 to 219145 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..597 218549..219145 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000088
SUMMARY PARAGRAPH for YAR062W

Flocculation, the calcium-dependent, non-sexual aggregation of yeast cells into 'flocs', is stimulated by nutrient limitation and is a process of great importance to the brewing characteristics of yeast strains (1). Characterization of flocculation characteristics has defined two classes of flocculation phenotypes. The FLO1-type is inhibited only by mannose sugars (3). The NewFLO-type, common in brewing strains, is inhibited by the sugars mannose, maltose, glucose, and sucrose, as well as by ammonium ions (3).

Sequence analysis suggests that the flocculation genes are a multi-gene family localized to telomeric sequences, similarly to the SUC, MEL, and MAL gene families, all of which also encode characteristics important for brewing strains (1). In addition to FLO1 and FLO5, there are thought to be two more flocculation genes and three pseudogenes. The FLO9 gene (YAL063C) is 94% similar to the FLO1 gene and may be the source of a 4.2-kb transcript whose presence is not affected by deletions of FLO1 or FLO5. The FLO10 gene (YKR102W) is 58% similar to FLO1, but has 81.9% similarity in the N-terminus (1). Three presumed pseudogenes, YAL065C, YAR061W and YAR062W, and YHR213W have also been identified as fragmentary pieces with sequence similarity to FLO1 (1).

Last updated: 2004-02-09 Contact SGD

References cited on this page View Complete Literature Guide for YAR062W
1) Teunissen AW and Steensma HY  (1995) Review: the dominant flocculation genes of Saccharomyces cerevisiae constitute a new subtelomeric gene family. Yeast 11(11):1001-13
2) Katju V, et al.  (2009) Variation in gene duplicates with low synonymous divergence in Saccharomyces cerevisiae relative to Caenorhabditis elegans. Genome Biol 10(7):R75
3) Stratford M  (1989) Evidence for two mechanisms of flocculation in Saccharomyces cerevisiae. Yeast 5 Spec No():S441-5