SWH1/YAR042W Summary Help

SWH1 BASIC INFORMATION

Standard Name SWH1 1
Systematic Name YAR042W
Alias YAR044W , OSH1 2
Feature Type ORF, Verified
Description Protein similar to mammalian oxysterol-binding protein; contains ankyrin repeats; localizes to the Golgi and the nucleus-vacuole junction (1, 3, 4)
GO Annotations All SWH1 GO evidence and references
    View Computational GO annotations for SWH1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All SWH1 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions SWH1 All interactions details and references
56 total interaction(s) for 39 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 16
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 2
  • Co-localization: 1
  • PCA: 3
  • Protein-RNA: 1
  • Two-hybrid: 1
Genetic Interactions
  • Dosage Lethality: 1
  • Dosage Rescue: 1
  • Phenotypic Enhancement: 23
  • Phenotypic Suppression: 4
  • Synthetic Growth Defect: 2
Sequence Information
ChrI:192613 to 196179 | ORF Map | GBrowse
This feature contains embedded feature(s): YAR044W
Gbrowse
Last Update Coordinates: 2004-07-20 | Sequence: 2006-01-19
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..3567 192613..196179 2004-07-20 2006-01-19
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS
Primary SGDIDS000000081

SWH1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for SWH1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for SWH1]

1) Schmalix WA and Bandlow W  (1994) SWH1 from yeast encodes a candidate nuclear factor containing ankyrin repeats and showing homology to mammalian oxysterol-binding protein. Biochim Biophys Acta 1219(1):205-10
2) Beh CT, et al.  (2001) Overlapping functions of the yeast oxysterol-binding protein homologues. Genetics 157(3):1117-40
3) Jiang B, et al.  (1994) A new family of yeast genes implicated in ergosterol synthesis is related to the human oxysterol binding protein. Yeast 10(3):341-53
4) Levine TP and Munro S  (2001) Dual targeting of Osh1p, a yeast homologue of oxysterol-binding protein, to both the Golgi and the nucleus-vacuole junction. Mol Biol Cell 12(6):1633-44