PRM9/YAR031W Summary Help

Standard Name PRM9 1
Systematic Name YAR031W
Feature Type ORF, Verified
Description Pheromone-regulated protein; contains 3 predicted transmembrane segments and an FF sequence, a motif involved in COPII binding; member of DUP240 gene family; PRM9 has a paralog, PRM8, that arose from a segmental duplication (1, 2, 3, 4, 5)
Name Description Pheromone-Regulated Membrane protein 1
Chromosomal Location
ChrI:186836 to 187732 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All PRM9 GO evidence and references
  View Computational GO annotations for PRM9
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 1 genes
Resources
Large-scale survey
null
overexpression
unspecified
Resources
24 total interaction(s) for 23 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Affinity Capture-RNA: 1
  • Co-purification: 1
  • PCA: 6
  • Two-hybrid: 2

Genetic Interactions
  • Negative Genetic: 5
  • Phenotypic Enhancement: 2
  • Positive Genetic: 1
  • Synthetic Growth Defect: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 298
Molecular Weight (Da) 35,073
Isoelectric Point (pI) 8.08
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrI:186836 to 187732 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..897 186836..187732 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000078
References cited on this page View Complete Literature Guide for PRM9
1) Heiman MG and Walter P  (2000) Prm1p, a pheromone-regulated multispanning membrane protein, facilitates plasma membrane fusion during yeast mating. J Cell Biol 151(3):719-30
2) Feuermann M, et al.  (1997) The characterization of two new clusters of duplicated genes suggests a 'Lego' organization of the yeast Saccharomyces cerevisiae chromosomes. Yeast 13(9):861-9
3) Sandmann T, et al.  (2003) Suppression of coatomer mutants by a new protein family with COPI and COPII binding motifs in Saccharomyces cerevisiae. Mol Biol Cell 14(8):3097-113
4) Poirey R, et al.  (2002) Functional analysis of the Saccharomyces cerevisiae DUP240 multigene family reveals membrane-associated proteins that are not essential for cell viability. Microbiology 148(Pt 7):2111-23
5) Katju V, et al.  (2009) Variation in gene duplicates with low synonymous divergence in Saccharomyces cerevisiae relative to Caenorhabditis elegans. Genome Biol 10(7):R75