NUP60/YAR002W Summary Help

NUP60 BASIC INFORMATION

Standard Name NUP60
Systematic Name YAR002W
Feature Type ORF, Verified
Description Subunit of the nuclear pore complex (NPC), functions to anchor Nup2p to the NPC in a process controlled by the nucleoplasmic concentration of Gsp1p-GTP; potential Cdc28p substrate; involved in telomere maintenance (1, 2, 3)
Name Description NUclear Pore
GO Annotations All NUP60 GO evidence and references
    View Computational GO annotations for NUP60
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All NUP60 Phenotype details and references
Large-scale survey
null
overexpression
Interactions NUP60 All interactions details and references
265 total interaction(s) for 142 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 40
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 11
  • Biochemical Activity: 3
  • Co-localization: 1
  • Co-purification: 1
  • PCA: 1
  • Reconstituted Complex: 6
Genetic Interactions
  • Dosage Rescue: 1
  • Phenotypic Enhancement: 89
  • Phenotypic Suppression: 21
  • Synthetic Growth Defect: 56
  • Synthetic Lethality: 33
  • Synthetic Rescue: 1
Sequence Information
ChrI:152259 to 153878 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2004-07-20 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1620 152259..153878 2004-07-20 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000000063

NUP60 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for NUP60

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for NUP60]

1) Denning D, et al.  (2001) The nucleoporin Nup60p functions as a Gsp1p-GTP-sensitive tether for Nup2p at the nuclear pore complex. J Cell Biol 154(5):937-50
2) Ubersax JA, et al.  (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64
3) Askree SH, et al.  (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63