FLO9/YAL063C Summary Help

Standard Name FLO9
Systematic Name YAL063C
Feature Type ORF, Verified
Description Lectin-like protein with similarity to Flo1p; thought to be expressed and involved in flocculation (1 and see Summary Paragraph)
Name Description FLOcculation
Chromosomal Location
ChrI:27968 to 24000 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All FLO9 GO evidence and references
  View Computational GO annotations for FLO9
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 111 genes
Resources
Classical genetics
overexpression
Large-scale survey
null
Resources
14 total interaction(s) for 14 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 2

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 10
  • Phenotypic Enhancement: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,322
Molecular Weight (Da) 138,072
Isoelectric Point (pI) 4
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrI:27968 to 24000 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3969 27968..24000 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000059
SUMMARY PARAGRAPH for FLO9

Flocculation, the calcium-dependent, non-sexual aggregation of yeast cells into 'flocs', is stimulated by nutrient limitation and is a process of great importance to the brewing characteristics of yeast strains (1). Characterization of flocculation characteristics has defined two classes of flocculation phenotypes. The FLO1-type is inhibited only by mannose sugars (2). The NewFLO-type, common in brewing strains, is inhibited by the sugars mannose, maltose, glucose, and sucrose, as well as by ammonium ions (2).

Sequence analysis suggests that the flocculation genes are a multi-gene family localized to telomeric sequences, similarly to the SUC, MEL, and MAL gene families, all of which also encode characteristics important for brewing strains (1). In addition to FLO1 and FLO5, there are thought to be two more flocculation genes and three pseudogenes. The FLO9 gene (YAL063C) is 94% similar to the FLO1 gene and may be the source of a 4.2-kb transcript whose presence is not affected by deletions of FLO1 or FLO5. The FLO10 gene (YKR102W) is 58% similar to FLO1, but has 81.9% similarity in the N-terminus (1). Three presumed pseudogenes, YAL065C, YAR061W and YAR062W, and YHR213W have also been identified as fragmentary pieces with sequence similarity to FLO1 (1).

Last updated: 2004-02-09 Contact SGD

References cited on this page View Complete Literature Guide for FLO9
1) Teunissen AW and Steensma HY  (1995) Review: the dominant flocculation genes of Saccharomyces cerevisiae constitute a new subtelomeric gene family. Yeast 11(11):1001-13
2) Stratford M  (1989) Evidence for two mechanisms of flocculation in Saccharomyces cerevisiae. Yeast 5 Spec No():S441-5