ECM1/YAL059W Summary Help

Standard Name ECM1 1
Systematic Name YAL059W
Feature Type ORF, Verified
Description Pre-ribosomal factor involved in 60S ribosomal protein subunit export; associates with the pre-60S particle; shuttles between the nucleus and cytoplasm (2, 3)
Name Description ExtraCellular Mutant
Chromosomal Location
ChrI:36509 to 37147 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All ECM1 GO evidence and references
  View Computational GO annotations for ECM1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 2 genes
Resources
Classical genetics
repressible
Large-scale survey
null
unspecified
Resources
86 total interaction(s) for 65 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 12
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 11
  • Two-hybrid: 3

Genetic Interactions
  • Dosage Growth Defect: 3
  • Negative Genetic: 34
  • Positive Genetic: 4
  • Synthetic Growth Defect: 13
  • Synthetic Lethality: 5

Resources
Expression Summary
histogram
Resources
Length (a.a.) 212
Molecular Weight (Da) 23,891
Isoelectric Point (pI) 10.44
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrI:36509 to 37147 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2011-02-03
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..639 36509..37147 2011-02-03 2011-02-03
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000055
References cited on this page View Complete Literature Guide for ECM1
1) Lussier M, et al.  (1997) Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae. Genetics 147(2):435-50
2) Bassler J, et al.  (2001) Identification of a 60S preribosomal particle that is closely linked to nuclear export. Mol Cell 8(3):517-29
3) Yao Y, et al.  (2010) Ecm1 is a new pre-ribosomal factor involved in pre-60S particle export. RNA 16(5):1007-17