PEX22/YAL055W Summary Help

Standard Name PEX22
Systematic Name YAL055W
Alias YAF5
Feature Type ORF, Verified
Description Putative peroxisomal membrane protein; required for import of peroxisomal proteins; functionally complements a Pichia pastoris pex22 mutation (1)
Name Description PEroXisome related
Chromosomal Location
ChrI:42177 to 42719 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All PEX22 GO evidence and references
  View Computational GO annotations for PEX22
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 3 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
65 total interaction(s) for 56 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 1
  • Co-crystal Structure: 2
  • PCA: 4
  • Reconstituted Complex: 1
  • Two-hybrid: 4

Genetic Interactions
  • Negative Genetic: 37
  • Positive Genetic: 7
  • Synthetic Growth Defect: 6
  • Synthetic Lethality: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 180
Molecular Weight (Da) 19,877
Isoelectric Point (pI) 8.33
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrI:42177 to 42719 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..543 42177..42719 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000051
References cited on this page View Complete Literature Guide for PEX22
1) Koller A, et al.  (1999) Pex22p of Pichia pastoris, essential for peroxisomal matrix protein import, anchors the ubiquitin-conjugating enzyme, Pex4p, on the peroxisomal membrane. J Cell Biol 146(1):99-112