FLC2/YAL053W Summary Help

Standard Name FLC2 1
Systematic Name YAL053W
Feature Type ORF, Verified
Description Putative FAD transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance; FLC2 has a paralog, YOR365C, that arose from the whole genome duplication (1, 2)
Name Description FLavin Carrier 1
Chromosomal Location
ChrI:45899 to 48250 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All FLC2 GO evidence and references
  View Computational GO annotations for FLC2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 8 genes
Resources
Classical genetics
null
unspecified
Large-scale survey
null
overexpression
Resources
69 total interaction(s) for 58 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 10
  • Affinity Capture-RNA: 2
  • PCA: 23

Genetic Interactions
  • Dosage Lethality: 1
  • Dosage Rescue: 10
  • Negative Genetic: 11
  • Phenotypic Suppression: 2
  • Positive Genetic: 2
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 5

Resources
Expression Summary
histogram
Resources
Length (a.a.) 783
Molecular Weight (Da) 87,468
Isoelectric Point (pI) 8.05
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrI:45899 to 48250 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2011-02-03
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2352 45899..48250 2011-02-03 2011-02-03
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Retired NameHUF2
Primary SGDIDS000000049
References cited on this page View Complete Literature Guide for FLC2
1) Protchenko O, et al.  (2006) A screen for genes of heme uptake identifies the FLC family required for import of FAD into the endoplasmic reticulum. J Biol Chem 281(30):21445-57
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61