ERV46/YAL042W Summary Help

Standard Name ERV46
Systematic Name YAL042W
Alias FUN9 1
Feature Type ORF, Verified
Description Protein localized to COPII-coated vesicles; forms a complex with Erv41p; involved in the membrane fusion stage of transport (2)
Name Description ER Vesicle
Chromosomal Location
ChrI:61316 to 62563 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All ERV46 GO evidence and references
  View Computational GO annotations for ERV46
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 11 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
118 total interaction(s) for 74 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 13
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 5
  • Biochemical Activity: 2
  • Co-fractionation: 1
  • Co-purification: 2
  • PCA: 3
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 67
  • Phenotypic Enhancement: 1
  • Positive Genetic: 13
  • Synthetic Growth Defect: 6
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 415
Molecular Weight (Da) 46,235
Isoelectric Point (pI) 6.81
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrI:61316 to 62563 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1248 61316..62563 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000040
References cited on this page View Complete Literature Guide for ERV46
1) Coleman KG, et al.  (1986) Molecular cloning of chromosome I DNA from Saccharomyces cerevisiae: isolation and characterization of the CDC24 gene and adjacent regions of the chromosome. Mol Cell Biol 6(12):4516-25
2) Otte S, et al.  (2001) Erv41p and Erv46p: new components of COPII vesicles involved in transport between the ER and Golgi complex. J Cell Biol 152(3):503-18