RBG1/YAL036C Summary Help

Standard Name RBG1 1, 2
Systematic Name YAL036C
Alias FUN11 3
Feature Type ORF, Verified
Description Member of the DRG family of GTP-binding proteins; associates with translating ribosomes; interacts with Tma46p, Ygr250cp, Gir2p and Yap1p via two-hybrid (2, 4, 5, 6)
Name Description RiBosome interacting Gtpase 1
Chromosomal Location
ChrI:76152 to 75043 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All RBG1 GO evidence and references
  View Computational GO annotations for RBG1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 5 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
54 total interaction(s) for 37 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 20
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 7
  • Co-crystal Structure: 1
  • Co-fractionation: 1
  • Reconstituted Complex: 1
  • Two-hybrid: 9

Genetic Interactions
  • Dosage Growth Defect: 1
  • Negative Genetic: 5
  • Synthetic Growth Defect: 5
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 369
Molecular Weight (Da) 40,701
Isoelectric Point (pI) 8.49
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrI:76152 to 75043 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1110 76152..75043 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000034
References cited on this page View Complete Literature Guide for RBG1
1) Wout, P. and Maddock, J.  (2004) The Saccharomyces cerevisiae Rig1p protein and its binding partner Gir2p, interact on polyribosomes with Gcn1p.
2) Datta K, et al.  (2005) The yeast GTPase Mtg2p is required for mitochondrial translation and partially suppresses an rRNA methyltransferase mutant, mrm2. Mol Biol Cell 16(2):954-63
3) Coleman KG, et al.  (1986) Molecular cloning of chromosome I DNA from Saccharomyces cerevisiae: isolation and characterization of the CDC24 gene and adjacent regions of the chromosome. Mol Cell Biol 6(12):4516-25
4) Li B and Trueb B  (2000) DRG represents a family of two closely related GTP-binding proteins. Biochim Biophys Acta 1491(1-3):196-204
5) Fleischer TC, et al.  (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307
6) Wout PK, et al.  (2009) Saccharomyces cerevisiae Rbg1 protein and its binding partner Gir2 interact on Polyribosomes with Gcn1. Eukaryot Cell 8(7):1061-71