Standard Name	FUN26
Systematic Name	YAL022C
Feature Type	ORF, Verified
Description	Vacuolar membrane transporter with broad nucleoside selectivity; may regulate balance of nicotinamide riboside (NmR) levels between cytosol and vacuole, contributing to salvage of NmR for use in cytosolic NAD+ synthesis (1, 2)
Name Description	Function Unknown Now 3

Chromosomal Location	ChrI:110430 to 108877 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for FUN26
Molecular Function
Manually curated	nicotinamide riboside transmembrane transporter activity (IMP) nucleoside transmembrane transporter activity (IDA)
Biological Process
Manually curated	nicotinamide riboside transport (IMP) nucleoside transport (IDA) transmembrane transport (IDA)
Cellular Component
Manually curated	fungal-type vacuole membrane (IDA) intracellular (IDA) membrane (IDA)
High-throughput	integral to membrane (ISM)

Classical genetics
null	N-ribosylnicotinamide accumulation: increased NAD(+) accumulation: decreased N-ribosylnicotinamide excretion: increased viable
Large-scale survey
null	UV resistance: decreased proton accumulation: decreased inositol excretion: increased competitive fitness: decreased resistance to L-canavanine: increased resistance to ethanol: decreased starvation resistance: decreased toxin resistance: decreased viable
overexpression	vegetative growth: decreased vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	10 total interaction(s) for 10 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 PCA: 4 Protein-RNA: 1 Two-hybrid: 1
Genetic Interactions	Dosage Lethality: 1 Negative Genetic: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrI:110430 to 108877 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1554 110430..108877 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain EC1118 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB

Primary SGDID	S000000020