TPD3/YAL016W Summary Help

TPD3 BASIC INFORMATION

Standard Name TPD3
Systematic Name YAL016W
Alias FUN32
Feature Type ORF, Verified
Description Regulatory subunit A of the heterotrimeric protein phosphatase 2A (PP2A), which also contains regulatory subunit Cdc55p and either catalytic subunit Pph21p or Pph22p; required for cell morphogenesis and transcription by RNA polymerase III (1, 2)
Name Description tRNA Processing Deficient 3
GO Annotations All TPD3 GO evidence and references
    View Computational GO annotations for TPD3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All TPD3 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions TPD3 All interactions details and references
99 total interaction(s) for 44 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 61
  • Affinity Capture-Western: 18
  • Co-fractionation: 2
  • PCA: 4
  • Two-hybrid: 8
Genetic Interactions
  • Phenotypic Enhancement: 1
  • Synthetic Haploinsufficiency: 1
  • Synthetic Lethality: 3
  • Synthetic Rescue: 1
Sequence Information
ChrI:124880 to 126787 | ORF Map | GBrowse
Gbrowse
Genetic position: .5 cM
Last Update Coordinates: 2004-07-20 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1908 124880..126787 2004-07-20 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000000014

TPD3 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Literature
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  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for TPD3

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for TPD3]

1) van Zyl W, et al.  (1992) Inactivation of the protein phosphatase 2A regulatory subunit A results in morphological and transcriptional defects in Saccharomyces cerevisiae. Mol Cell Biol 12(11):4946-59
2) Wang Y and Burke DJ  (1997) Cdc55p, the B-type regulatory subunit of protein phosphatase 2A, has multiple functions in mitosis and is required for the kinetochore/spindle checkpoint in Saccharomyces cerevisiae. Mol Cell Biol 17(2):620-6
3) van Zyl WH, et al.  (1989) A general screen for mutant of Saccharomyces cerevisiae deficient in tRNA biosynthesis. Genetics 123(1):55-68