GO term: methionine biosynthetic process 
Ontology: Biological Process (GO:0009086)
Definition: The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
Synonyms: methionine anabolism; methionine biosynthesis; methionine formation; methionine synthesis
View Ontology:
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(text)
Definition: The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
Synonyms: methionine anabolism; methionine biosynthesis; methionine formation; methionine synthesis
View Ontology:
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This table lists the methods used to annotate genes either directly to the term
methionine biosynthetic process (31 genes)
or to its variants containing one or more
qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | methionine biosynthetic process | 9 |
| High-throughput | none | none |
| Computational (download data) | methionine biosynthetic process | 28 |
Links to Additional Annotations:
- View
annotations in multiple organisms using
- Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.
Annotation details for genes that have been directly annotated to the term
methionine biosynthetic process or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| methionine biosynthetic process 31 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| ADE3/YGR204W | IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| ADI1/YMR009W | IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| HOM2/YDR158W | IMP: Inferred from Mutant Phenotype Assigned on 2012-05-10 |
manually curated | Robichon-Szulmajster H, et al. (1966) Genetic and biochemical studies of genes controlling the synthesis of threonine and methionine in Saccharomyces. Genetics 53(3):609-19 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:IPR012080, EBI:IPR005676 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro | |
| IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| HOM3/YER052C | IMP: Inferred from Mutant Phenotype Assigned on 2012-05-14 |
manually curated | Robichon-Szulmajster H, et al. (1966) Genetic and biochemical studies of genes controlling the synthesis of threonine and methionine in Saccharomyces. Genetics 53(3):609-19 |
SGD |
| HOM6/YJR139C | IMP: Inferred from Mutant Phenotype Assigned on 2012-05-14 |
manually curated | Robichon-Szulmajster H, et al. (1966) Genetic and biochemical studies of genes controlling the synthesis of threonine and methionine in Saccharomyces. Genetics 53(3):609-19 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| IRC7/YFR055W | IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| MDE1/YJR024C | IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| MET1/YKR069W | IMP: Inferred from Mutant Phenotype Assigned on 2006-07-24 |
manually curated | Masselot M and De Robichon-Szulmajster H (1975) Methionine biosynthesis in Saccharomyces cerevisiae. I. Genetical analysis of auxotrophic mutants. Mol Gen Genet 139(2):121-32 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| MET10/YFR030W | IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| MET13/YGL125W | IMP: Inferred from Mutant Phenotype, ISS: Inferred from Sequence or structural Similarity with EBI:P0AEZ1, EBI:P42898 Assigned on 2008-08-05 |
manually curated | Raymond RK, et al. (1999) Saccharomyces cerevisiae expresses two genes encoding isozymes of methylenetetrahydrofolate reductase. Arch Biochem Biophys 372(2):300-8 |
SGD |
| IMP: Inferred from Mutant Phenotype, ISS: Inferred from Sequence or structural Similarity with EBI:P0AEZ1, EBI:P42898 Assigned on 2008-08-04 |
manually curated | Tizon B, et al. (1999) Disruption of six novel Saccharomyces cerevisiae genes reveals that YGL129c is necessary for growth in non-fermentable carbon sources, YGL128c for growth at low or high temperatures and YGL125w is implicated in the biosynthesis of methionine. Yeast 15(2):145-54 |
SGD | |
| MET14/YKL001C | IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| MET16/YPR167C | IEA: Inferred from Electronic Annotation with EBI:IPR011800 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| MET17/YLR303W | IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| MET2/YNL277W | IMP: Inferred from Mutant Phenotype Assigned on 2012-08-14 |
manually curated | Robichon-Szulmajster H and Cherest H (1967) Regulation of homoserine O-transacetylase, first step in methionine biosyntheis in Saccharomyces cerevisiae. Biochem Biophys Res Commun 28(2):256-62 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:IPR008220 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro | |
| IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| MET22/YOL064C | IMP: Inferred from Mutant Phenotype Assigned on 2010-06-11 |
manually curated | Glaser HU, et al. (1993) Salt tolerance and methionine biosynthesis in Saccharomyces cerevisiae involve a putative phosphatase gene. EMBO J 12(8):3105-10 |
SGD |
| MET28/YIR017C | IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| MET3/YJR010W | IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| MET30/YIL046W | IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| MET4/YNL103W | IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| MET5/YJR137C | IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| MET6/YER091C | IMP: Inferred from Mutant Phenotype Assigned on 2003-05-28 |
manually curated | Masselot M and De Robichon-Szulmajster H (1975) Methionine biosynthesis in Saccharomyces cerevisiae. I. Genetical analysis of auxotrophic mutants. Mol Gen Genet 139(2):121-32 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:IPR002629, EBI:IPR006276 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro | |
| IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| MET8/YBR213W | IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| MHT1/YLL062C | IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| MIS1/YBR084W | IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| MRI1/YPR118W | IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| SAM4/YPL273W | IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| STR2/YJR130C | IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| STR3/YGL184C | IMP: Inferred from Mutant Phenotype Assigned on 2002-11-04 |
manually curated | Hansen J and Johannesen PF (2000) Cysteine is essential for transcriptional regulation of the sulfur assimilation genes in Saccharomyces cerevisiae. Mol Gen Genet 263(3):535-42 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| UTR4/YEL038W | IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| YLL058W | IEA: Inferred from Electronic Annotation with EBI:KW-0486 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
