Ontology: Biological Process (GO:0009060)
Definition: The enzymatic release of energy from organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor.
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(text)
Definition: The enzymatic release of energy from organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor.
View Ontology:
(graph) |
This table lists the methods used to annotate genes either directly to the term
aerobic respiration (57 genes)
or to its variants containing one or more
qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | aerobic respiration | 53 |
| High-throughput | none | none |
| Computational (download data) | aerobic respiration | 5 |
Links to Additional Annotations:
- View
annotations in multiple organisms using

- Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.
Annotation details for genes that have been directly annotated to the term
aerobic respiration or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| aerobic respiration 57 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| AAC1/YMR056C | IGI: Inferred from Genetic Interaction with SGD:PET9 Assigned on 2004-02-26 |
manually curated | Gawaz M, et al. (1990) Structure-function studies of adenine nucleotide transport in mitochondria. II. Biochemical analysis of distinct AAC1 and AAC2 proteins in yeast. J Biol Chem 265(24):14202-8 | SGD |
| ADE16/YLR028C | IEP: Inferred from Expression Pattern Assigned on 2001-06-26 |
manually curated | Tibbetts AS and Appling DR (2000) Characterization of two 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase isozymes from Saccharomyces cerevisiae. J Biol Chem 275(27):20920-7 | SGD |
| AI2/Q0055 | IEA: Inferred from Electronic Annotation with EBI:IPR000883 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| AI3/Q0060 | IEA: Inferred from Electronic Annotation with EBI:IPR000883 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| AI4/Q0065 | IEA: Inferred from Electronic Annotation with EBI:IPR000883 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| AI5_ALPHA/Q0070 | IEA: Inferred from Electronic Annotation with EBI:IPR000883 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| ALG6/YOR002W | IMP: Inferred from Mutant Phenotype Assigned on 2007-04-18 |
manually curated | Mendelsohn RD, et al. (2005) A hypomorphic allele of the first N-glycosylation gene, ALG7, causes mitochondrial defects in yeast. Biochim Biophys Acta 1723(1-3):33-44 | SGD |
| ALG7/YBR243C | IMP: Inferred from Mutant Phenotype Assigned on 2007-04-18 |
manually curated | Mendelsohn RD, et al. (2005) A hypomorphic allele of the first N-glycosylation gene, ALG7, causes mitochondrial defects in yeast. Biochim Biophys Acta 1723(1-3):33-44 | SGD |
| CBP1/YJL209W | IMP: Inferred from Mutant Phenotype Assigned on 2002-09-18 |
manually curated | Chen W and Dieckmann CL (1997) Genetic evidence for interaction between Cbp1 and specific nucleotides in the 5' untranslated region of mitochondrial cytochrome b mRNA in Saccharomyces cerevisiae. Mol Cell Biol 17(11):6203-11 | SGD |
| COB/Q0105 | IMP: Inferred from Mutant Phenotype Assigned on 2002-09-06 |
manually curated | Kreike J, et al. (1979) The identification of apocytochrome b as a mitochondrial gene product and immunological evidence for altered apocytochrome b in yeast strains having mutations in the COB region of mitochondrial DNA. Eur J Biochem 101(2):607-17 | SGD |
| COQ5/YML110C | IMP: Inferred from Mutant Phenotype Assigned on 2002-09-13 |
manually curated | Barkovich RJ, et al. (1997) Characterization of the COQ5 gene from Saccharomyces cerevisiae. Evidence for a C-methyltransferase in ubiquinone biosynthesis. J Biol Chem 272(14):9182-8 | SGD |
| COQ8/YGL119W | IMP: Inferred from Mutant Phenotype Assigned on 2005-09-06 |
manually curated | Bousquet I, et al. (1991) ABC1, a novel yeast nuclear gene has a dual function in mitochondria: it suppresses a cytochrome b mRNA translation defect and is essential for the electron transfer in the bc 1 complex. EMBO J 10(8):2023-31 | SGD |
| COQ9/YLR201C | IMP: Inferred from Mutant Phenotype Assigned on 2005-09-06 |
manually curated | Johnson A, et al. (2005) COQ9, a new gene required for the biosynthesis of coenzyme Q in Saccharomyces cerevisiae. J Biol Chem 280(36):31397-404 | SGD |
| COR1/YBL045C | IMP: Inferred from Mutant Phenotype Assigned on 2002-09-06 |
manually curated | Gatti DL and Tzagoloff A (1990) Structure and function of the mitochondrial bc1 complex. Properties of the complex in temperature-sensitive cor1 mutants. J Biol Chem 265(35):21468-75 | SGD |
| COX1/Q0045 | IMP: Inferred from Mutant Phenotype Assigned on 2002-06-03 |
manually curated | Lemaire C, et al. (1998) Molecular and biochemical analysis of Saccharomyces cerevisiae cox1 mutants. Curr Genet 34(2):138-45 | SGD |
| IEA: Inferred from Electronic Annotation with EBI:IPR000883 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro | |
| COX11/YPL132W | IMP: Inferred from Mutant Phenotype Assigned on 2002-06-04 |
manually curated | Hiser L, et al. (2000) Cox11p is required for stable formation of the Cu(B) and magnesium centers of cytochrome c oxidase. J Biol Chem 275(1):619-23 | SGD |
| COX13/YGL191W | IMP: Inferred from Mutant Phenotype Assigned on 2002-06-14 |
manually curated | Taanman JW and Capaldi RA (1993) Subunit VIa of yeast cytochrome c oxidase is not necessary for assembly of the enzyme complex but modulates the enzyme activity. Isolation and characterization of the nuclear-coded gene. J Biol Chem 268(25):18754-61 | SGD |
| COX2/Q0250 | IMP: Inferred from Mutant Phenotype Assigned on 2002-09-05 |
manually curated | Fox TD (1979) Genetic and physical analysis of the mitochondrial gene for subunit II of yeast cytochrome c oxidase. J Mol Biol 130(1):63-82 | SGD |
| COX20/YDR231C | IMP: Inferred from Mutant Phenotype Assigned on 2002-06-04 |
manually curated | Hell K, et al. (2000) Identification of Cox20p, a novel protein involved in the maturation and assembly of cytochrome oxidase subunit 2. J Biol Chem 275(7):4571-8 | SGD |
| COX3/Q0275 | IMP: Inferred from Mutant Phenotype Assigned on 2002-06-04 |
manually curated | Meunier B (2001) Site-directed mutations in the mitochondrially encoded subunits I and III of yeast cytochrome oxidase. Biochem J 354(Pt 2):407-12 | SGD |
| COX4/YGL187C | IPI: Inferred from Physical Interaction Assigned on 2002-09-16 |
manually curated | Eytan GD and Schatz G (1975) Cytochrome c oxidase from bakers' yeast. V. Arrangement of the subunits in the isolated and membrane-bound enzyme. J Biol Chem 250(2):767-74 | SGD |
| DLD1/YDL174C | IMP: Inferred from Mutant Phenotype Assigned on 2002-06-05 |
manually curated | Lodi T and Ferrero I (1993) Isolation of the DLD gene of Saccharomyces cerevisiae encoding the mitochondrial enzyme D-lactate ferricytochrome c oxidoreductase. Mol Gen Genet 238(3):315-24 | SGD |
| ETR1/YBR026C | IMP: Inferred from Mutant Phenotype Assigned on 2002-10-30 |
manually curated | Torkko JM, et al. (2001) Candida tropicalis Etr1p and Saccharomyces cerevisiae Ybr026p (Mrf1'p), 2-enoyl thioester reductases essential for mitochondrial respiratory competence. Mol Cell Biol 21(18):6243-53 | SGD |
| GDS1/YOR355W | IGI: Inferred from Genetic Interaction, IMP: Inferred from Mutant Phenotype Assigned on 2002-09-30 |
manually curated | Konopinska A, et al. (1995) Nucleotide sequence of the GDS1 gene of Saccharomyces cerevisiae. Yeast 11(15):1513-8 | SGD |
| ISF1/YMR081C | IGI: Inferred from Genetic Interaction Assigned on 2002-09-30 |
manually curated | Daignan-Fornier B, et al. (1994) MBR1 and MBR3, two related yeast genes that can suppress the growth defect of hap2, hap3 and hap4 mutants. Mol Gen Genet 243(5):575-83 | SGD |
| JAC1/YGL018C | IMP: Inferred from Mutant Phenotype Assigned on 2001-01-18 |
manually curated | Strain J, et al. (1998) Suppressors of superoxide dismutase (SOD1) deficiency in Saccharomyces cerevisiae. Identification of proteins predicted to mediate iron-sulfur cluster assembly. J Biol Chem 273(47):31138-44 | SGD |
| MAM33/YIL070C | IMP: Inferred from Mutant Phenotype Assigned on 2002-06-05 |
manually curated | Muta T, et al. (1997) p32 protein, a splicing factor 2-associated protein, is localized in mitochondrial matrix and is functionally important in maintaining oxidative phosphorylation. J Biol Chem 272(39):24363-70 | SGD |
| MBR1/YKL093W | IMP: Inferred from Mutant Phenotype Assigned on 2002-09-30 |
manually curated | Daignan-Fornier B, et al. (1994) MBR1 and MBR3, two related yeast genes that can suppress the growth defect of hap2, hap3 and hap4 mutants. Mol Gen Genet 243(5):575-83 | SGD |
| MCT1/YOR221C | IMP: Inferred from Mutant Phenotype Assigned on 2002-10-28 |
manually curated | Schneider R, et al. (1997) Two genes of the putative mitochondrial fatty acid synthase in the genome of Saccharomyces cerevisiae. Curr Genet 32(6):384-8 | SGD |
| MDH1/YKL085W | IMP: Inferred from Mutant Phenotype Assigned on 2008-08-25 |
manually curated | McAlister-Henn L and Thompson LM (1987) Isolation and expression of the gene encoding yeast mitochondrial malate dehydrogenase. J Bacteriol 169(11):5157-66 | SGD |



