GO term: aerobic respiration Help



Ontology: Biological Process (GO:0009060)

Definition: The enzymatic release of energy from organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor.

View Ontology: GO Tree Graph (graph) | Amigo (text)

Annotation Summary


This table lists the methods used to annotate genes either directly to the term aerobic respiration (57 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method GO Term # Yeast Genes Annotated
Manually curated (download data) aerobic respiration 53
High-throughput none none
Computational (download data) aerobic respiration 5

Links to Additional Annotations:
Genes Annotated with this Term
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Annotation details for genes that have been directly annotated to the term aerobic respiration or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

aerobic respiration
     57 genes directly annotated to this term
Locus Evidence Annotation Method Reference Assigned By
AAC1/YMR056C IGI: Inferred from Genetic Interaction
with SGD:PET9
Assigned on 2004-02-26
manually curated Gawaz M, et al.  (1990) Structure-function studies of adenine nucleotide transport in mitochondria. II. Biochemical analysis of distinct AAC1 and AAC2 proteins in yeast. J Biol Chem 265(24):14202-8 SGD
ADE16/YLR028C IEP: Inferred from Expression Pattern
Assigned on 2001-06-26
manually curated Tibbetts AS and Appling DR  (2000) Characterization of two 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase isozymes from Saccharomyces cerevisiae. J Biol Chem 275(27):20920-7 SGD
AI2/Q0055 IEA: Inferred from Electronic Annotation
with EBI:IPR000883
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
AI3/Q0060 IEA: Inferred from Electronic Annotation
with EBI:IPR000883
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
AI4/Q0065 IEA: Inferred from Electronic Annotation
with EBI:IPR000883
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
AI5_ALPHA/Q0070 IEA: Inferred from Electronic Annotation
with EBI:IPR000883
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
ALG6/YOR002W IMP: Inferred from Mutant Phenotype
Assigned on 2007-04-18
manually curated Mendelsohn RD, et al.  (2005) A hypomorphic allele of the first N-glycosylation gene, ALG7, causes mitochondrial defects in yeast. Biochim Biophys Acta 1723(1-3):33-44 SGD
ALG7/YBR243C IMP: Inferred from Mutant Phenotype
Assigned on 2007-04-18
manually curated Mendelsohn RD, et al.  (2005) A hypomorphic allele of the first N-glycosylation gene, ALG7, causes mitochondrial defects in yeast. Biochim Biophys Acta 1723(1-3):33-44 SGD
CBP1/YJL209W IMP: Inferred from Mutant Phenotype
Assigned on 2002-09-18
manually curated Chen W and Dieckmann CL  (1997) Genetic evidence for interaction between Cbp1 and specific nucleotides in the 5' untranslated region of mitochondrial cytochrome b mRNA in Saccharomyces cerevisiae. Mol Cell Biol 17(11):6203-11 SGD
COB/Q0105 IMP: Inferred from Mutant Phenotype
Assigned on 2002-09-06
manually curated Kreike J, et al.  (1979) The identification of apocytochrome b as a mitochondrial gene product and immunological evidence for altered apocytochrome b in yeast strains having mutations in the COB region of mitochondrial DNA. Eur J Biochem 101(2):607-17 SGD
COQ5/YML110C IMP: Inferred from Mutant Phenotype
Assigned on 2002-09-13
manually curated Barkovich RJ, et al.  (1997) Characterization of the COQ5 gene from Saccharomyces cerevisiae. Evidence for a C-methyltransferase in ubiquinone biosynthesis. J Biol Chem 272(14):9182-8 SGD
COQ8/YGL119W IMP: Inferred from Mutant Phenotype
Assigned on 2005-09-06
manually curated Bousquet I, et al.  (1991) ABC1, a novel yeast nuclear gene has a dual function in mitochondria: it suppresses a cytochrome b mRNA translation defect and is essential for the electron transfer in the bc 1 complex. EMBO J 10(8):2023-31 SGD
COQ9/YLR201C IMP: Inferred from Mutant Phenotype
Assigned on 2005-09-06
manually curated Johnson A, et al.  (2005) COQ9, a new gene required for the biosynthesis of coenzyme Q in Saccharomyces cerevisiae. J Biol Chem 280(36):31397-404 SGD
COR1/YBL045C IMP: Inferred from Mutant Phenotype
Assigned on 2002-09-06
manually curated Gatti DL and Tzagoloff A  (1990) Structure and function of the mitochondrial bc1 complex. Properties of the complex in temperature-sensitive cor1 mutants. J Biol Chem 265(35):21468-75 SGD
COX1/Q0045 IMP: Inferred from Mutant Phenotype
Assigned on 2002-06-03
manually curated Lemaire C, et al.  (1998) Molecular and biochemical analysis of Saccharomyces cerevisiae cox1 mutants. Curr Genet 34(2):138-45 SGD
IEA: Inferred from Electronic Annotation
with EBI:IPR000883
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
COX11/YPL132W IMP: Inferred from Mutant Phenotype
Assigned on 2002-06-04
manually curated Hiser L, et al.  (2000) Cox11p is required for stable formation of the Cu(B) and magnesium centers of cytochrome c oxidase. J Biol Chem 275(1):619-23 SGD
COX13/YGL191W IMP: Inferred from Mutant Phenotype
Assigned on 2002-06-14
manually curated Taanman JW and Capaldi RA  (1993) Subunit VIa of yeast cytochrome c oxidase is not necessary for assembly of the enzyme complex but modulates the enzyme activity. Isolation and characterization of the nuclear-coded gene. J Biol Chem 268(25):18754-61 SGD
COX2/Q0250 IMP: Inferred from Mutant Phenotype
Assigned on 2002-09-05
manually curated Fox TD  (1979) Genetic and physical analysis of the mitochondrial gene for subunit II of yeast cytochrome c oxidase. J Mol Biol 130(1):63-82 SGD
COX20/YDR231C IMP: Inferred from Mutant Phenotype
Assigned on 2002-06-04
manually curated Hell K, et al.  (2000) Identification of Cox20p, a novel protein involved in the maturation and assembly of cytochrome oxidase subunit 2. J Biol Chem 275(7):4571-8 SGD
COX3/Q0275 IMP: Inferred from Mutant Phenotype
Assigned on 2002-06-04
manually curated Meunier B  (2001) Site-directed mutations in the mitochondrially encoded subunits I and III of yeast cytochrome oxidase. Biochem J 354(Pt 2):407-12 SGD
COX4/YGL187C IPI: Inferred from Physical Interaction
Assigned on 2002-09-16
manually curated Eytan GD and Schatz G  (1975) Cytochrome c oxidase from bakers' yeast. V. Arrangement of the subunits in the isolated and membrane-bound enzyme. J Biol Chem 250(2):767-74 SGD
DLD1/YDL174C IMP: Inferred from Mutant Phenotype
Assigned on 2002-06-05
manually curated Lodi T and Ferrero I  (1993) Isolation of the DLD gene of Saccharomyces cerevisiae encoding the mitochondrial enzyme D-lactate ferricytochrome c oxidoreductase. Mol Gen Genet 238(3):315-24 SGD
ETR1/YBR026C IMP: Inferred from Mutant Phenotype
Assigned on 2002-10-30
manually curated Torkko JM, et al.  (2001) Candida tropicalis Etr1p and Saccharomyces cerevisiae Ybr026p (Mrf1'p), 2-enoyl thioester reductases essential for mitochondrial respiratory competence. Mol Cell Biol 21(18):6243-53 SGD
GDS1/YOR355W IGI: Inferred from Genetic Interaction,
IMP: Inferred from Mutant Phenotype
Assigned on 2002-09-30
manually curated Konopinska A, et al.  (1995) Nucleotide sequence of the GDS1 gene of Saccharomyces cerevisiae. Yeast 11(15):1513-8 SGD
ISF1/YMR081C IGI: Inferred from Genetic Interaction
Assigned on 2002-09-30
manually curated Daignan-Fornier B, et al.  (1994) MBR1 and MBR3, two related yeast genes that can suppress the growth defect of hap2, hap3 and hap4 mutants. Mol Gen Genet 243(5):575-83 SGD
JAC1/YGL018C IMP: Inferred from Mutant Phenotype
Assigned on 2001-01-18
manually curated Strain J, et al.  (1998) Suppressors of superoxide dismutase (SOD1) deficiency in Saccharomyces cerevisiae. Identification of proteins predicted to mediate iron-sulfur cluster assembly. J Biol Chem 273(47):31138-44 SGD
MAM33/YIL070C IMP: Inferred from Mutant Phenotype
Assigned on 2002-06-05
manually curated Muta T, et al.  (1997) p32 protein, a splicing factor 2-associated protein, is localized in mitochondrial matrix and is functionally important in maintaining oxidative phosphorylation. J Biol Chem 272(39):24363-70 SGD
MBR1/YKL093W IMP: Inferred from Mutant Phenotype
Assigned on 2002-09-30
manually curated Daignan-Fornier B, et al.  (1994) MBR1 and MBR3, two related yeast genes that can suppress the growth defect of hap2, hap3 and hap4 mutants. Mol Gen Genet 243(5):575-83 SGD
MCT1/YOR221C IMP: Inferred from Mutant Phenotype
Assigned on 2002-10-28
manually curated Schneider R, et al.  (1997) Two genes of the putative mitochondrial fatty acid synthase in the genome of Saccharomyces cerevisiae. Curr Genet 32(6):384-8 SGD
MDH1/YKL085W IMP: Inferred from Mutant Phenotype
Assigned on 2008-08-25
manually curated McAlister-Henn L and Thompson LM  (1987) Isolation and expression of the gene encoding yeast mitochondrial malate dehydrogenase. J Bacteriol 169(11):5157-66 SGD