Ontology: Molecular Function (GO:0008650)

Definition: Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methyluridine.

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term rRNA (uridine-2'-O-)-methyltransferase activity (2 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	rRNA (uridine-2'-O-)-methyltransferase activity	2
High-throughput	none	none
Computational	none	none

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term rRNA (uridine-2'-O-)-methyltransferase activity or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

rRNA (uridine-2'-O-)-methyltransferase activity      2 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
MRM2/YGL136C	IDA: Inferred from Direct Assay, IMP: Inferred from Mutant Phenotype Assigned on 2002-03-13	manually curated	Pintard L, et al.  (2002) MRM2 encodes a novel yeast mitochondrial 21S rRNA methyltransferase. EMBO J 21(5):1139-47	SGD
	IMP: Inferred from Mutant Phenotype Assigned on 2006-05-12	manually curated	Bonnerot C, et al.  (2003) Functional redundancy of Spb1p and a snR52-dependent mechanism for the 2'-O-ribose methylation of a conserved rRNA position in yeast. Mol Cell 12(5):1309-15	SGD
SPB1/YCL054W	IGI: Inferred from Genetic Interaction with SGD:SNR52 Assigned on 2006-05-12	manually curated	Bonnerot C, et al.  (2003) Functional redundancy of Spb1p and a snR52-dependent mechanism for the 2'-O-ribose methylation of a conserved rRNA position in yeast. Mol Cell 12(5):1309-15	SGD

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