Ontology: Molecular Function (GO:0008554)

Definition: Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) -> ADP + phosphate + Na+(out); by a phosphorylative mechanism.

Synonyms: hydrogen-/sodium-translocating ATPase activity; Na(+)-exporting ATPase activity; Na(+)-transporting ATPase activity; sodium exporting ATPase activity, phosphorylative mechanism; sodium transport ATPase activity; sodium-translocating P-type ATPase activity; ATP phosphohydrolase (Na+-exporting); Na+-exporting ATPase activity; Na+-transporting ATPase activity; sodium-exporting ATPase activity

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term sodium-exporting ATPase activity, phosphorylative mechanism (3 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	sodium-exporting ATPase activity, phosphorylative mechanism	2
High-throughput	none	none
Computational (download data)	sodium-exporting ATPase activity, phosphorylative mechanism	3

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term sodium-exporting ATPase activity, phosphorylative mechanism or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

sodium-exporting ATPase activity, phosphorylative mechanism      3 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
ENA1/YDR040C	IDA: Inferred from Direct Assay Assigned on 2006-10-25	manually curated	Benito B, et al.  (1997) Overexpression of the sodium ATPase of Saccharomyces cerevisiae: conditions for phosphorylation from ATP and Pi. Biochim Biophys Acta 1328(2):214-26	SGD
	IGI: Inferred from Genetic Interaction with SGD:ENA2 Assigned on 2006-10-25	manually curated	Haro R, et al.  (1991) A novel P-type ATPase from yeast involved in sodium transport. FEBS Lett 291(2):189-91	SGD
	IEA: Inferred from Electronic Annotation with IUBMB:3.6.3.7 Last Updated 2013-03-02	computational	GOA curators and MGI curators  (2001) Gene Ontology annotation based on Enzyme Commission mapping.	UniProtKB
ENA2/YDR039C	IGI: Inferred from Genetic Interaction with SGD:ENA1 Assigned on 2006-10-25	manually curated	Haro R, et al.  (1991) A novel P-type ATPase from yeast involved in sodium transport. FEBS Lett 291(2):189-91	SGD
	ISS: Inferred from Sequence or structural Similarity with SGD:ENA1 Assigned on 2006-10-25	manually curated	Garciadeblas B, et al.  (1993) Differential expression of two genes encoding isoforms of the ATPase involved in sodium efflux in Saccharomyces cerevisiae. Mol Gen Genet 236(2-3):363-8	SGD
	IEA: Inferred from Electronic Annotation with IUBMB:3.6.3.7 Last Updated 2013-03-02	computational	GOA curators and MGI curators  (2001) Gene Ontology annotation based on Enzyme Commission mapping.	UniProtKB
ENA5/YDR038C	IEA: Inferred from Electronic Annotation with IUBMB:3.6.3.7 Last Updated 2013-03-02	computational	GOA curators and MGI curators  (2001) Gene Ontology annotation based on Enzyme Commission mapping.	UniProtKB

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