GO term: peptidase activity Help



Ontology: Molecular Function (GO:0008233)

Definition: Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.

Synonyms: hydrolase, acting on peptide bonds; peptide hydrolase activity; protease activity; proteinase activity

View Ontology: GO Tree Graph (graph) | Amigo (text)

Annotation Summary


This table lists the methods used to annotate genes either directly to the term peptidase activity (159 genes) or to its variants containing one or more qualifiers (1 gene). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method GO Term # Yeast Genes Annotated
Manually curated (download data) contributes_to: peptidase activity 1
peptidase activity 53
High-throughput none none
Computational (download data) peptidase activity 154

Links to Additional Annotations:
Genes Annotated with this Term
Jump to: top | Annotation Summary


Annotation details for genes that have been directly annotated to the term peptidase activity or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

peptidase activity
     159 genes directly annotated to this term
Locus Evidence Annotation Method Reference Assigned By
AAP1/YHR047C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
AFG3/YER017C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
APE1/YKL103C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
APE2/YKL157W IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
APE3/YBR286W IEA: Inferred from Electronic Annotation
with EBI:IPR007484
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
APE4/YHR113W IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
ARX1/YDR101C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
ATG4/YNL223W IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
ATP23/YNR020C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
AXL1/YPR122W IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
BAR1/YIL015W IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
CPS1/YJL172W IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
CYM1/YDR430C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
DAP2/YHR028C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
DOA4/YDR069C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
DUG1/YFR044C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
DUG2/YBR281C IGI: Inferred from Genetic Interaction
with SGD:MET17
Assigned on 2008-08-20
manually curated Ganguli D, et al.  (2007) The Alternative Pathway of Glutathione Degradation Is Mediated by a Novel Protein Complex Involving Three New Genes in Saccharomyces cerevisiae. Genetics 175(3):1137-51 SGD
IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
DUG3/YNL191W IGI: Inferred from Genetic Interaction
with SGD:MET17
Assigned on 2008-08-20
manually curated Ganguli D, et al.  (2007) The Alternative Pathway of Glutathione Degradation Is Mediated by a Novel Protein Complex Involving Three New Genes in Saccharomyces cerevisiae. Genetics 175(3):1137-51 SGD
ECM14/YHR132C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
ESP1/YGR098C IEA: Inferred from Electronic Annotation
with EBI:IPR005314
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
FRA1/YLL029W IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
GPI8/YDR331W IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
HSP31/YDR533C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
HSP32/YPL280W IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
HSP33/YOR391C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
ICP55/YER078C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
IMP1/YMR150C IEA: Inferred from Electronic Annotation
with EBI:IPR026730
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
IMP2/YMR035W IEA: Inferred from Electronic Annotation
with EBI:IPR026726
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
KEX1/YGL203C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
KEX2/YNL238W IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB

contributes_to: peptidase activity
     1 gene directly annotated to this term
Locus Evidence Annotation Method Reference Assigned By
SPC2/YML055W IMP: Inferred from Mutant Phenotype
Assigned on 2011-01-13
manually curated Antonin W, et al.  (2000) Interactions between Spc2p and other components of the endoplasmic reticulum translocation sites of the yeast Saccharomyces cerevisiae. J Biol Chem 275(44):34068-72 SGD