GO term: enzyme activator activity 
Ontology: Molecular Function (GO:0008047)
Definition: Increases the activity of an enzyme.
Definition: Increases the activity of an enzyme.
This table lists the methods used to annotate genes either directly to the term
enzyme activator activity (21 genes)
or to its variants containing one or more
qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | enzyme activator activity | 14 |
| High-throughput | none | none |
| Computational (download data) | enzyme activator activity | 7 |
Links to Additional Annotations:
Annotation details for genes that have been directly annotated to the term
enzyme activator activity or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| enzyme activator activity 21 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| AMA1/YGR225W | IMP: Inferred from Mutant Phenotype, IPI: Inferred from Physical Interaction Assigned on 2005-05-11 |
manually curated | Cooper KF, et al. (2000) Ama1p is a meiosis-specific regulator of the anaphase promoting complex/cyclosome in yeast. Proc Natl Acad Sci U S A 97(26):14548-53 |
SGD |
| ARC1/YGL105W | IDA: Inferred from Direct Assay Assigned on 2007-11-12 |
manually curated | Deinert K, et al. (2001) Arc1p organizes the yeast aminoacyl-tRNA synthetase complex and stabilizes its interaction with the cognate tRNAs. J Biol Chem 276(8):6000-8 |
SGD |
| CLA4/YNL298W | RCA: Reviewed Computational Analysis Assigned on 2009-09-03 |
computational | Tian W, et al. (2008) Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function. Genome Biol 9 Suppl 1:S7 |
YeastFunc |
| DCP1/YOL149W | IDA: Inferred from Direct Assay Assigned on 2006-01-23 |
manually curated | She M, et al. (2006) Crystal structure and functional analysis of Dcp2p from Schizosaccharomyces pombe. Nat Struct Mol Biol 13(1):63-70 |
SGD |
| ECM25/YJL201W | RCA: Reviewed Computational Analysis Assigned on 2009-09-03 |
computational | Tian W, et al. (2008) Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function. Genome Biol 9 Suppl 1:S7 |
YeastFunc |
| FRQ1/YDR373W | IDA: Inferred from Direct Assay Assigned on 2004-02-27 |
manually curated | Hendricks KB, et al. (1999) Yeast homologue of neuronal frequenin is a regulator of phosphatidylinositol-4-OH kinase. Nat Cell Biol 1(4):234-41 |
SGD |
| GLC8/YMR311C | IDA: Inferred from Direct Assay Assigned on 2002-09-19 |
manually curated | Nigavekar SS, et al. (2002) Glc8 is a glucose-repressible activator of Glc7 protein phosphatase-1. Arch Biochem Biophys 404(1):71-9 |
SGD |
| GLE1/YDL207W | IDA: Inferred from Direct Assay, IGI: Inferred from Genetic Interaction with SGD:DBP5, IMP: Inferred from Mutant Phenotype Assigned on 2009-01-23 |
manually curated | Weirich CS, et al. (2006) Activation of the DExD/H-box protein Dbp5 by the nuclear-pore protein Gle1 and its coactivator InsP6 is required for mRNA export. Nat Cell Biol 8(7):668-76 |
SGD |
| GYL1/YMR192W | RCA: Reviewed Computational Analysis Assigned on 2009-09-03 |
computational | Tian W, et al. (2008) Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function. Genome Biol 9 Suppl 1:S7 |
YeastFunc |
| MGS1/YNL218W | IDA: Inferred from Direct Assay Assigned on 2007-08-03 |
manually curated | Kim JH, et al. (2005) In vivo and in vitro studies of Mgs1 suggest a link between genome instability and Okazaki fragment processing. Nucleic Acids Res 33(19):6137-50 |
SGD |
| MOB1/YIL106W | RCA: Reviewed Computational Analysis Assigned on 2009-09-03 |
computational | Tian W, et al. (2008) Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function. Genome Biol 9 Suppl 1:S7 |
YeastFunc |
| RCL1/YOL010W | IDA: Inferred from Direct Assay Assigned on 2009-05-22 |
manually curated | Karbstein K, et al. (2005) An essential GTPase promotes assembly of preribosomal RNA processing complexes. Mol Cell 20(4):633-43 |
SGD |
| RMI1/YPL024W | IDA: Inferred from Direct Assay Assigned on 2008-10-24 |
manually curated | Chen CF and Brill SJ (2007) Binding and activation of DNA topoisomerase III by the Rmi1 subunit. J Biol Chem 282(39):28971-9 |
SGD |
| SHC1/YER096W | IGI: Inferred from Genetic Interaction Assigned on 2002-11-04 |
manually curated | Sanz M, et al. (2002) Control of chitin synthesis through Shc1p, a functional homologue of Chs4p specifically induced during sporulation. Mol Microbiol 43(5):1183-95 |
SGD |
| SKT5/YBL061C | IMP: Inferred from Mutant Phenotype Assigned on 2001-01-18 |
manually curated | Trilla JA, et al. (1997) Characterization of CHS4 (CAL2), a gene of Saccharomyces cerevisiae involved in chitin biosynthesis and allelic to SKT5 and CSD4. Yeast 13(9):795-807 |
SGD |
| SPS18/YNL204C | RCA: Reviewed Computational Analysis Assigned on 2009-09-03 |
computational | Tian W, et al. (2008) Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function. Genome Biol 9 Suppl 1:S7 |
YeastFunc |
| SSK1/YLR006C | TAS: Traceable Author Statement Assigned on 2001-01-18 |
manually curated | Posas F and Saito H (1998) Activation of the yeast SSK2 MAP kinase kinase kinase by the SSK1 two-component response regulator. EMBO J 17(5):1385-94 |
SGD |
| STE20/YHL007C | RCA: Reviewed Computational Analysis Assigned on 2009-09-03 |
computational | Tian W, et al. (2008) Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function. Genome Biol 9 Suppl 1:S7 |
YeastFunc |
| TSC3/YBR058C-A | IDA: Inferred from Direct Assay Assigned on 2002-09-25 |
manually curated | Gable K, et al. (2000) Tsc3p is an 80-amino acid protein associated with serine palmitoyltransferase and required for optimal enzyme activity. J Biol Chem 275(11):7597-603 |
SGD |
| VAC14/YLR386W | IMP: Inferred from Mutant Phenotype Assigned on 2002-10-31 |
manually curated | Bonangelino CJ, et al. (2002) Osmotic stress-induced increase of phosphatidylinositol 3,5-bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p. J Cell Biol 156(6):1015-28 |
SGD |
| IMP: Inferred from Mutant Phenotype Assigned on 2007-02-14 |
manually curated | Duex JE, et al. (2006) The Vac14p-Fig4p complex acts independently of Vac7p and couples PI3,5P2 synthesis and turnover. J Cell Biol 172(5):693-704 |
SGD | |
| YHR182W | RCA: Reviewed Computational Analysis Assigned on 2009-09-03 |
computational | Tian W, et al. (2008) Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function. Genome Biol 9 Suppl 1:S7 |
YeastFunc |
This diagram shows the local area of the Gene Ontology and the numbers of yeast genes annotated to each term in the diagram. Within the diagram, click on the blue arrow to navigate up the tree and click on a GO term name to go to its GO term page.
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