Ontology: Biological Process (GO:0000729)

Definition: The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang.

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term DNA double-strand break processing (4 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	DNA double-strand break processing	4
High-throughput	none	none
Computational	none	none

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term DNA double-strand break processing or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

DNA double-strand break processing      4 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
EXO1/YOR033C	IGI: Inferred from Genetic Interaction with SGD:TEL1, IMP: Inferred from Mutant Phenotype Assigned on 2007-03-14	manually curated	Mantiero D, et al.  (2007) Dual role for Saccharomyces cerevisiae Tel1 in the checkpoint response to double-strand breaks. EMBO Rep 8(4):380-7	SGD
FUN30/YAL019W	IMP: Inferred from Mutant Phenotype Assigned on 2012-09-25	manually curated	Costelloe T, et al.  (2012) The yeast Fun30 and human SMARCAD1 chromatin remodellers promote DNA end resection. Nature 489(7417):581-4	SGD
	IMP: Inferred from Mutant Phenotype Assigned on 2012-10-04	manually curated	Chen X, et al.  (2012) The Fun30 nucleosome remodeller promotes resection of DNA double-strand break ends. Nature 489(7417):576-80	SGD
SAE2/YGL175C	IGI: Inferred from Genetic Interaction with SGD:RAD51, SGD:EXO1 Assigned on 2008-12-05	manually curated	Mimitou EP and Symington LS  (2008) Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing. Nature 455(7214):770-4	SGD
SGS1/YMR190C	IGI: Inferred from Genetic Interaction with SGD:EXO1, SGD:RAD51 Assigned on 2008-12-05	manually curated	Mimitou EP and Symington LS  (2008) Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing. Nature 455(7214):770-4	SGD

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