GO term: signal transduction 
Ontology: Biological Process (GO:0007165)
Definition: The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
Synonyms: signaling cascade; signalling cascade; signalling pathway; signaling pathway
View Ontology:
(graph) | 
(text)
Definition: The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
Synonyms: signaling cascade; signalling cascade; signalling pathway; signaling pathway
View Ontology:
(graph) | (text)
This table lists the methods used to annotate genes either directly to the term
signal transduction (70 genes)
or to its variants containing one or more
qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | signal transduction | 30 |
| High-throughput | none | none |
| Computational (download data) | signal transduction | 44 |
Links to Additional Annotations:
- View
annotations in multiple organisms using
- Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.
Annotation details for genes that have been directly annotated to the term
signal transduction or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| signal transduction 70 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| STE3/YKL178C | IEA: Inferred from Electronic Annotation with EBI:KW-0807 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| STE4/YOR212W | IEA: Inferred from Electronic Annotation with EBI:KW-0807 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| STE50/YCL032W | IEA: Inferred from Electronic Annotation with EBI:IPR000159 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro |
| SYG1/YIL047C | IMP: Inferred from Mutant Phenotype Assigned on 2001-01-18 |
manually curated | Spain BH, et al. (1995) Truncated forms of a novel yeast protein suppress the lethality of a G protein alpha subunit deficiency by interacting with the beta subunit. J Biol Chem 270(43):25435-44 |
SGD |
| TIP41/YPR040W | IMP: Inferred from Mutant Phenotype, IPI: Inferred from Physical Interaction Assigned on 2003-01-08 |
manually curated | Jacinto E, et al. (2001) TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway. Mol Cell 8(5):1017-26 |
SGD |
| TOR1/YJR066W | TAS: Traceable Author Statement Assigned on 2001-01-18 |
manually curated | Barbet NC, et al. (1996) TOR controls translation initiation and early G1 progression in yeast. Mol Biol Cell 7(1):25-42 |
SGD |
| TOR2/YKL203C | TAS: Traceable Author Statement Assigned on 2001-01-18 |
manually curated | Helliwell SB, et al. (1994) TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast. Mol Biol Cell 5(1):105-18 |
SGD |
| TUS1/YLR425W | IGI: Inferred from Genetic Interaction, IMP: Inferred from Mutant Phenotype Assigned on 2002-10-30 |
manually curated | Schmelzle T, et al. (2002) Yeast protein kinases and the RHO1 exchange factor TUS1 are novel components of the cell integrity pathway in yeast. Mol Cell Biol 22(5):1329-39 |
SGD |
| YHR182W | IEA: Inferred from Electronic Annotation with EBI:IPR008936, EBI:IPR000198 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro |
| YIL169C | IEA: Inferred from Electronic Annotation with EBI:IPR004089 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro |
