Ontology: Biological Process (GO:0070481)
Definition: The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that is lacking a stop codon.
Synonyms: non-stop decay; non-stop mRNA decay; nonstop mRNA decay; nuclear-transcribed mRNA breakdown, non-stop decay; nuclear-transcribed mRNA catabolism, non-stop decay; nuclear-transcribed mRNA degradation, non-stop decay
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(text)
Definition: The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that is lacking a stop codon.
Synonyms: non-stop decay; non-stop mRNA decay; nonstop mRNA decay; nuclear-transcribed mRNA breakdown, non-stop decay; nuclear-transcribed mRNA catabolism, non-stop decay; nuclear-transcribed mRNA degradation, non-stop decay
View Ontology:
(graph) |
This table lists the methods used to annotate genes either directly to the term
nuclear-transcribed mRNA catabolic process, non-stop decay (20 genes)
or to its variants containing one or more
qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | nuclear-transcribed mRNA catabolic process, non-stop decay | 20 |
| High-throughput | none | none |
| Computational | none | none |
Links to Additional Annotations:
- View
annotations in multiple organisms using

- Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.
Annotation details for genes that have been directly annotated to the term
nuclear-transcribed mRNA catabolic process, non-stop decay or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| nuclear-transcribed mRNA catabolic process, non-stop decay 20 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| CSL4/YNL232W | IMP: Inferred from Mutant Phenotype Assigned on 2009-03-06 |
manually curated | van Hoof A, et al. (2002) Exosome-mediated recognition and degradation of mRNAs lacking a termination codon. Science 295(5563):2262-4 | SGD |
| DIS3/YOL021C | IC: Inferred By Curator from cytoplasmic exosome (RNase complex) Assigned on 2009-03-13 |
manually curated | Allmang C, et al. (1999) The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases. Genes Dev 13(16):2148-58 | SGD |
| HTZ1/YOL012C | IMP: Inferred from Mutant Phenotype Assigned on 2009-03-06 |
manually curated | Wilson MA, et al. (2007) A genomic screen in yeast reveals novel aspects of nonstop mRNA metabolism. Genetics 177(2):773-84 | SGD |
| IPK1/YDR315C | IMP: Inferred from Mutant Phenotype Assigned on 2009-03-06 |
manually curated | Wilson MA, et al. (2007) A genomic screen in yeast reveals novel aspects of nonstop mRNA metabolism. Genetics 177(2):773-84 | SGD |
| IRC25/YLR021W | IMP: Inferred from Mutant Phenotype Assigned on 2009-03-06 |
manually curated | Wilson MA, et al. (2007) A genomic screen in yeast reveals novel aspects of nonstop mRNA metabolism. Genetics 177(2):773-84 | SGD |
| MTR3/YGR158C | IC: Inferred By Curator from cytoplasmic exosome (RNase complex) Assigned on 2009-03-13 |
manually curated | Allmang C, et al. (1999) The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases. Genes Dev 13(16):2148-58 | SGD |
| RRP4/YHR069C | IC: Inferred By Curator from cytoplasmic exosome (RNase complex) Assigned on 2009-03-13 |
manually curated | Allmang C, et al. (1999) The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases. Genes Dev 13(16):2148-58 | SGD |
| RRP40/YOL142W | IC: Inferred By Curator from cytoplasmic exosome (RNase complex) Assigned on 2009-03-13 |
manually curated | Allmang C, et al. (1999) The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases. Genes Dev 13(16):2148-58 | SGD |
| RRP42/YDL111C | IC: Inferred By Curator from cytoplasmic exosome (RNase complex) Assigned on 2009-03-13 |
manually curated | Allmang C, et al. (1999) The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases. Genes Dev 13(16):2148-58 | SGD |
| RRP43/YCR035C | IC: Inferred By Curator from cytoplasmic exosome (RNase complex) Assigned on 2009-03-13 |
manually curated | Allmang C, et al. (1999) The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases. Genes Dev 13(16):2148-58 | SGD |
| RRP45/YDR280W | IC: Inferred By Curator from cytoplasmic exosome (RNase complex) Assigned on 2009-03-13 |
manually curated | Allmang C, et al. (1999) The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases. Genes Dev 13(16):2148-58 | SGD |
| RRP46/YGR095C | IC: Inferred By Curator from cytoplasmic exosome (RNase complex) Assigned on 2009-03-13 |
manually curated | Allmang C, et al. (1999) The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases. Genes Dev 13(16):2148-58 | SGD |
| SIR3/YLR442C | IMP: Inferred from Mutant Phenotype Assigned on 2009-03-06 |
manually curated | Wilson MA, et al. (2007) A genomic screen in yeast reveals novel aspects of nonstop mRNA metabolism. Genetics 177(2):773-84 | SGD |
| SKI2/YLR398C | IMP: Inferred from Mutant Phenotype Assigned on 2009-03-06 |
manually curated | van Hoof A, et al. (2002) Exosome-mediated recognition and degradation of mRNAs lacking a termination codon. Science 295(5563):2262-4 | SGD |
| IMP: Inferred from Mutant Phenotype Assigned on 2009-03-06 |
manually curated | Wilson MA, et al. (2007) A genomic screen in yeast reveals novel aspects of nonstop mRNA metabolism. Genetics 177(2):773-84 | SGD | |
| SKI3/YPR189W | IMP: Inferred from Mutant Phenotype Assigned on 2009-03-06 |
manually curated | van Hoof A, et al. (2002) Exosome-mediated recognition and degradation of mRNAs lacking a termination codon. Science 295(5563):2262-4 | SGD |
| IMP: Inferred from Mutant Phenotype Assigned on 2009-03-06 |
manually curated | Wilson MA, et al. (2007) A genomic screen in yeast reveals novel aspects of nonstop mRNA metabolism. Genetics 177(2):773-84 | SGD | |
| SKI6/YGR195W | IC: Inferred By Curator from cytoplasmic exosome (RNase complex) Assigned on 2009-03-13 |
manually curated | Allmang C, et al. (1999) The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases. Genes Dev 13(16):2148-58 | SGD |
| SKI7/YOR076C | IMP: Inferred from Mutant Phenotype Assigned on 2009-03-06 |
manually curated | van Hoof A, et al. (2002) Exosome-mediated recognition and degradation of mRNAs lacking a termination codon. Science 295(5563):2262-4 | SGD |
| IMP: Inferred from Mutant Phenotype Assigned on 2009-03-06 |
manually curated | Wilson MA, et al. (2007) A genomic screen in yeast reveals novel aspects of nonstop mRNA metabolism. Genetics 177(2):773-84 | SGD | |
| SKI8/YGL213C | IMP: Inferred from Mutant Phenotype Assigned on 2009-03-06 |
manually curated | van Hoof A, et al. (2002) Exosome-mediated recognition and degradation of mRNAs lacking a termination codon. Science 295(5563):2262-4 | SGD |
| IMP: Inferred from Mutant Phenotype Assigned on 2009-03-06 |
manually curated | Wilson MA, et al. (2007) A genomic screen in yeast reveals novel aspects of nonstop mRNA metabolism. Genetics 177(2):773-84 | SGD | |
| SSN3/YPL042C | IMP: Inferred from Mutant Phenotype Assigned on 2009-03-06 |
manually curated | Wilson MA, et al. (2007) A genomic screen in yeast reveals novel aspects of nonstop mRNA metabolism. Genetics 177(2):773-84 | SGD |
| YGR122W | IMP: Inferred from Mutant Phenotype Assigned on 2009-03-06 |
manually curated | Wilson MA, et al. (2007) A genomic screen in yeast reveals novel aspects of nonstop mRNA metabolism. Genetics 177(2):773-84 | SGD |




