Ontology: Biological Process (GO:0007010)

Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.

Synonyms: cytoskeletal organization and biogenesis; cytoskeletal regulator activity; cytoskeleton organization and biogenesis; cytoskeleton organisation

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term cytoskeleton organization (9 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	cytoskeleton organization	9
High-throughput	none	none
Computational (download data)	cytoskeleton organization	1

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term cytoskeleton organization or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

cytoskeleton organization      9 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
BUD14/YAR014C	IGI: Inferred from Genetic Interaction, IMP: Inferred from Mutant Phenotype, IPI: Inferred from Physical Interaction Assigned on 2005-09-26	manually curated	Knaus M, et al.  (2005) The Bud14p-Glc7p complex functions as a cortical regulator of dynein in budding yeast. EMBO J 24(17):3000-11	SGD
CMD1/YBR109C	IMP: Inferred from Mutant Phenotype Assigned on 2001-01-18	manually curated	Ohya Y and Botstein D  (1994) Diverse essential functions revealed by complementing yeast calmodulin mutants. Science 263(5149):963-6	SGD
HSP42/YDR171W	IGI: Inferred from Genetic Interaction, IMP: Inferred from Mutant Phenotype Assigned on 2001-01-18	manually curated	Gu J, et al.  (1997) Small heat shock protein suppression of Vpr-induced cytoskeletal defects in budding yeast. Mol Cell Biol 17(7):4033-42	SGD
MDM20/YOL076W	IMP: Inferred from Mutant Phenotype Assigned on 2002-05-17	manually curated	Hermann GJ, et al.  (1997) The yeast gene, MDM20, is necessary for mitochondrial inheritance and organization of the actin cytoskeleton. J Cell Biol 137(1):141-53	SGD
NAT3/YPR131C	IGI: Inferred from Genetic Interaction with SGD:MDM20, IMP: Inferred from Mutant Phenotype Assigned on 2005-06-15	manually curated	Singer JM and Shaw JM  (2003) Mdm20 protein functions with Nat3 protein to acetylate Tpm1 protein and regulate tropomyosin-actin interactions in budding yeast. Proc Natl Acad Sci U S A 100(13):7644-9	SGD
PFD1/YJL179W	IMP: Inferred from Mutant Phenotype Assigned on 2002-10-28	manually curated	Vainberg IE, et al.  (1998) Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin. Cell 93(5):863-73	SGD
SRV2/YNL138W	TAS: Traceable Author Statement Assigned on 2001-01-18	manually curated	Freeman NL, et al.  (1996) A conserved proline-rich region of the Saccharomyces cerevisiae cyclase-associated protein binds SH3 domains and modulates cytoskeletal localization. Mol Cell Biol 16(2):548-56	SGD
	IEA: Inferred from Electronic Annotation with EBI:IPR013912, EBI:IPR013992, EBI:IPR018106, EBI:IPR001837 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
STH1/YIL126W	IGI: Inferred from Genetic Interaction with SGD:MID2, SGD:SLG1, IMP: Inferred from Mutant Phenotype Assigned on 2007-02-15	manually curated	Chai B, et al.  (2002) Yeast RSC function is required for organization of the cellular cytoskeleton via an alternative PKC1 pathway. Genetics 161(2):575-84	SGD
TOR2/YKL203C	IMP: Inferred from Mutant Phenotype Assigned on 2001-01-18	manually curated	Helliwell SB, et al.  (1998) TOR2 is part of two related signaling pathways coordinating cell growth in Saccharomyces cerevisiae. Genetics 148(1):99-112	SGD

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