GO term: mitochondrion organization 
Ontology: Biological Process (GO:0007005)
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
Synonyms: mitochondrion organization and biogenesis; mitochondria organization; mitochondrion organisation
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
Synonyms: mitochondrion organization and biogenesis; mitochondria organization; mitochondrion organisation
This table lists the methods used to annotate genes either directly to the term
mitochondrion organization (39 genes)
or to its variants containing one or more
qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | mitochondrion organization | 39 |
| High-throughput | none | none |
| Computational (download data) | mitochondrion organization | 2 |
Links to Additional Annotations:
Annotation details for genes that have been directly annotated to the term
mitochondrion organization or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| mitochondrion organization 39 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| ATP11/YNL315C | IMP: Inferred from Mutant Phenotype Assigned on 2007-09-26 |
manually curated | Ackerman SH and Tzagoloff A (1990) Identification of two nuclear genes (ATP11, ATP12) required for assembly of the yeast F1-ATPase. Proc Natl Acad Sci U S A 87(13):4986-90 |
SGD |
| BCS1/YDR375C | IMP: Inferred from Mutant Phenotype Assigned on 2007-09-26 |
manually curated | Cruciat CM, et al. (1999) Bcs1p, an AAA-family member, is a chaperone for the assembly of the cytochrome bc(1) complex. EMBO J 18(19):5226-33 |
SGD |
| CLU1/YMR012W | IMP: Inferred from Mutant Phenotype Assigned on 2003-04-23 |
manually curated | Fields SD, et al. (1998) The S. cerevisiae CLU1 and D. discoideum cluA genes are functional homologues that influence mitochondrial morphology and distribution. J Cell Sci 111 ( Pt 12):1717-27 |
SGD |
| DNM1/YLL001W | IMP: Inferred from Mutant Phenotype Assigned on 2005-04-26 |
manually curated | Otsuga D, et al. (1998) The dynamin-related GTPase, Dnm1p, controls mitochondrial morphology in yeast. J Cell Biol 143(2):333-49 |
SGD |
| ERG29/YMR134W | IMP: Inferred from Mutant Phenotype Assigned on 2005-11-11 |
manually curated | Altmann K and Westermann B (2005) Role of essential genes in mitochondrial morphogenesis in Saccharomyces cerevisiae. Mol Biol Cell 16(11):5410-7 |
SGD |
| FZO1/YBR179C | TAS: Traceable Author Statement Assigned on 2001-01-18 |
manually curated | Hermann GJ and Shaw JM (1998) Mitochondrial dynamics in yeast. Annu Rev Cell Dev Biol 14:265-303 |
SGD |
| GET1/YGL020C | IMP: Inferred from Mutant Phenotype Assigned on 2002-11-14 |
manually curated | Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53 |
SGD |
| MAM3/YOL060C | IMP: Inferred from Mutant Phenotype Assigned on 2002-09-30 |
manually curated | Entian KD, et al. (1999) Functional analysis of 150 deletion mutants in Saccharomyces cerevisiae by a systematic approach. Mol Gen Genet 262(4-5):683-702 |
SGD |
| MDM1/YML104C | TAS: Traceable Author Statement Assigned on 2001-01-18 |
manually curated | Hermann GJ and Shaw JM (1998) Mitochondrial dynamics in yeast. Annu Rev Cell Dev Biol 14:265-303 |
SGD |
| MDM10/YAL010C | TAS: Traceable Author Statement Assigned on 2001-01-18 |
manually curated | Hermann GJ and Shaw JM (1998) Mitochondrial dynamics in yeast. Annu Rev Cell Dev Biol 14:265-303 |
SGD |
| MDM12/YOL009C | TAS: Traceable Author Statement Assigned on 2001-01-18 |
manually curated | Hermann GJ and Shaw JM (1998) Mitochondrial dynamics in yeast. Annu Rev Cell Dev Biol 14:265-303 |
SGD |
| MDM30/YLR368W | IMP: Inferred from Mutant Phenotype Assigned on 2002-11-14 |
manually curated | Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53 |
SGD |
| MDM31/YHR194W | IMP: Inferred from Mutant Phenotype Assigned on 2002-11-14 |
manually curated | Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53 |
SGD |
| IMP: Inferred from Mutant Phenotype Assigned on 2005-12-21 |
manually curated | Kucejova B, et al. (2005) A screen for nigericin-resistant yeast mutants revealed genes controlling mitochondrial volume and mitochondrial cation homeostasis. Genetics 171(2):517-26 |
SGD | |
| IEA: Inferred from Electronic Annotation with EBI:IPR012571 Last Updated 2009-11-20 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
UniProtKB | |
| MDM32/YOR147W | IMP: Inferred from Mutant Phenotype Assigned on 2002-11-14 |
manually curated | Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53 |
SGD |
| IMP: Inferred from Mutant Phenotype Assigned on 2005-12-21 |
manually curated | Kucejova B, et al. (2005) A screen for nigericin-resistant yeast mutants revealed genes controlling mitochondrial volume and mitochondrial cation homeostasis. Genetics 171(2):517-26 |
SGD | |
| IEA: Inferred from Electronic Annotation with EBI:IPR012571 Last Updated 2009-11-20 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
UniProtKB | |
| MDM34/YGL219C | IMP: Inferred from Mutant Phenotype Assigned on 2002-11-14 |
manually curated | Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53 |
SGD |
| MDM35/YKL053C-A | IMP: Inferred from Mutant Phenotype Assigned on 2002-11-14 |
manually curated | Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53 |
SGD |
| MDM36/YPR083W | IMP: Inferred from Mutant Phenotype Assigned on 2002-11-14 |
manually curated | Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53 |
SGD |
| MDM38/YOL027C | IMP: Inferred from Mutant Phenotype Assigned on 2002-11-14 |
manually curated | Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53 |
SGD |
| MFB1/YDR219C | IMP: Inferred from Mutant Phenotype Assigned on 2006-06-27 |
manually curated | Kondo-Okamoto N, et al. (2006) The novel F-box protein Mfb1p regulates mitochondrial connectivity and exhibits asymmetric localization in yeast. Mol Biol Cell 17(9):3756-67 |
SGD |
| MGM1/YOR211C | TAS: Traceable Author Statement Assigned on 2001-01-18 |
manually curated | Hermann GJ and Shaw JM (1998) Mitochondrial dynamics in yeast. Annu Rev Cell Dev Biol 14:265-303 |
SGD |
| IMP: Inferred from Mutant Phenotype Assigned on 2004-12-15 |
manually curated | Amutha B, et al. (2004) A novel role of Mgm1p, a dynamin-related GTPase, in ATP synthase assembly and cristae formation/maintenance. Biochem J 381(Pt 1):19-23 |
SGD | |
| MMM1/YLL006W | IMP: Inferred from Mutant Phenotype Assigned on 2002-11-21 |
manually curated | Burgess SM, et al. (1994) MMM1 encodes a mitochondrial outer membrane protein essential for establishing and maintaining the structure of yeast mitochondria. J Cell Biol 126(6):1375-91 |
SGD |
| MSH1/YHR120W | IMP: Inferred from Mutant Phenotype Assigned on 2006-08-16 |
manually curated | Reenan RA and Kolodner RD (1992) Characterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: evidence for separate mitochondrial and nuclear functions. Genetics 132(4):975-85 |
SGD |
| IMP: Inferred from Mutant Phenotype Assigned on 2006-08-16 |
manually curated | Mookerjee SA, et al. (2005) Analysis of the functional domains of the mismatch repair homologue Msh1p and its role in mitochondrial genome maintenance. Curr Genet 47(2):84-99 |
SGD | |
| NCA3/YJL116C | IGI: Inferred from Genetic Interaction Assigned on 2002-08-21 |
manually curated | Pelissier P, et al. (1995) NCA3, a nuclear gene involved in the mitochondrial expression of subunits 6 and 8 of the Fo-F1 ATP synthase of S. cerevisiae. Curr Genet 27(5):409-16 |
SGD |
| NGR1/YBR212W | IMP: Inferred from Mutant Phenotype Assigned on 2004-09-15 |
manually curated | Buu LM, et al. (2004) The yeast RNA-binding protein Rbp1p modifies the stability of mitochondrial porin mRNA. J Biol Chem 279(1):453-62 |
SGD |
| PCP1/YGR101W | IMP: Inferred from Mutant Phenotype Assigned on 2002-11-14 |
manually curated | Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53 |
SGD |
| POR1/YNL055C | IMP: Inferred from Mutant Phenotype Assigned on 2002-09-19 |
manually curated | Sanchez NS, et al. (2001) Requirements of Cyc2p and the porin, Por1p, for ionic stability and mitochondrial integrity in Saccharomyces cerevisiae. Arch Biochem Biophys 392(2):326-32 |
SGD |
| PUF3/YLL013C | IMP: Inferred from Mutant Phenotype Assigned on 2007-02-16 |
manually curated | Garcia-Rodriguez LJ, et al. (2007) Puf3p, a Pumilio family RNA binding protein, localizes to mitochondria and regulates mitochondrial biogenesis and motility in budding yeast. J Cell Biol 176(2):197-207 |
SGD |
| RPM2/YML091C | IGI: Inferred from Genetic Interaction Assigned on 2002-02-07 |
manually curated | Stribinskis V, et al. (2001) Rpm2, the protein subunit of mitochondrial RNase P in Saccharomyces cerevisiae, also has a role in the translation of mitochondrially encoded subunits of cytochrome c oxidase. Genetics 158(2):573-85 |
SGD |
| RRG9/YNL213C | IMP: Inferred from Mutant Phenotype Assigned on 2003-01-20 |
manually curated | Wysocki R, et al. (1999) Disruption and basic phenotypic analysis of 18 novel genes from the yeast Saccharomyces cerevisiae. Yeast 15(2):165-71 |
SGD |
| RSP5/YER125W | IGI: Inferred from Genetic Interaction with SGD:MDM1, IMP: Inferred from Mutant Phenotype Assigned on 2008-10-13 |
manually curated | Fisk HA and Yaffe MP (1999) A role for ubiquitination in mitochondrial inheritance in Saccharomyces cerevisiae. J Cell Biol 145(6):1199-208 |
SGD |
This diagram shows the local area of the Gene Ontology and the numbers of yeast genes annotated to each term in the diagram. Within the diagram, click on the blue arrow to navigate up the tree and click on a GO term name to go to its GO term page.
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