GO term: response to DNA damage stimulus 
Ontology: Biological Process (GO:0006974)
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
Synonyms: DNA damage response; response to genotoxic stress; cellular DNA damage response; cellular response to DNA damage stimulus
View Ontology:
(graph) | 
(text)
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
Synonyms: DNA damage response; response to genotoxic stress; cellular DNA damage response; cellular response to DNA damage stimulus
View Ontology:
(graph) | (text)
This table lists the methods used to annotate genes either directly to the term
response to DNA damage stimulus (205 genes)
or to its variants containing one or more
qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | response to DNA damage stimulus | 36 |
| High-throughput (download data) | response to DNA damage stimulus | 13 |
| Computational (download data) | response to DNA damage stimulus | 173 |
Links to Additional Annotations:
- View
annotations in multiple organisms using
- Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.
Annotation details for genes that have been directly annotated to the term
response to DNA damage stimulus or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| response to DNA damage stimulus 205 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| ABF1/YKL112W | IEA: Inferred from Electronic Annotation with EBI:KW-0227 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| ALK1/YGL021W | IEA: Inferred from Electronic Annotation with EBI:KW-0227 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| ALK2/YBL009W | IEA: Inferred from Electronic Annotation with EBI:KW-0227 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| AOS1/YPR180W | IEA: Inferred from Electronic Annotation with EBI:KW-0227 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| APN1/YKL114C | IEA: Inferred from Electronic Annotation with EBI:KW-0227 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| APN2/YBL019W | IEA: Inferred from Electronic Annotation with EBI:KW-0227 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| ARP4/YJL081C | IEA: Inferred from Electronic Annotation with EBI:KW-0227 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| ARP8/YOR141C | IMP: Inferred from Mutant Phenotype Assigned on 2007-05-11 |
manually curated | Kawashima S, et al. (2007) The INO80 complex is required for damage-induced recombination. Biochem Biophys Res Commun 355(3):835-41 |
SGD |
| BDF1/YLR399C | IEA: Inferred from Electronic Annotation with EBI:KW-0227 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| BDF2/YDL070W | IEA: Inferred from Electronic Annotation with EBI:KW-0227 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| BUD25/YER014C-A | IEA: Inferred from Electronic Annotation with EBI:KW-0227 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| CDC9/YDL164C | IEA: Inferred from Electronic Annotation with EBI:KW-0227 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| CHK1/YBR274W | IEA: Inferred from Electronic Annotation with EBI:KW-0227 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| CKA1/YIL035C | IDA: Inferred from Direct Assay Assigned on 2002-10-22 |
manually curated | Ghavidel A and Schultz MC (2001) TATA binding protein-associated CK2 transduces DNA damage signals to the RNA polymerase III transcriptional machinery. Cell 106(5):575-84 |
SGD |
| CKA2/YOR061W | IDA: Inferred from Direct Assay Assigned on 2002-10-22 |
manually curated | Ghavidel A and Schultz MC (2001) TATA binding protein-associated CK2 transduces DNA damage signals to the RNA polymerase III transcriptional machinery. Cell 106(5):575-84 |
SGD |
| CKB1/YGL019W | IDA: Inferred from Direct Assay Assigned on 2002-10-22 |
manually curated | Ghavidel A and Schultz MC (2001) TATA binding protein-associated CK2 transduces DNA damage signals to the RNA polymerase III transcriptional machinery. Cell 106(5):575-84 |
SGD |
| CKB2/YOR039W | IDA: Inferred from Direct Assay Assigned on 2002-10-22 |
manually curated | Ghavidel A and Schultz MC (2001) TATA binding protein-associated CK2 transduces DNA damage signals to the RNA polymerase III transcriptional machinery. Cell 106(5):575-84 |
SGD |
| CSM2/YIL132C | IEA: Inferred from Electronic Annotation with EBI:KW-0227 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| CSM3/YMR048W | IEA: Inferred from Electronic Annotation with EBI:IPR012923 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0227 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| CST9/YLR394W | IEA: Inferred from Electronic Annotation with EBI:KW-0227 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| CTK1/YKL139W | IEA: Inferred from Electronic Annotation with EBI:KW-0227 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| CTK2/YJL006C | IEA: Inferred from Electronic Annotation with EBI:KW-0227 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| CTK3/YML112W | IEA: Inferred from Electronic Annotation with EBI:KW-0227 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| DCC1/YCL016C | IMP: Inferred from Mutant Phenotype Assigned on 2006-04-06 |
high-throughput | Chang M, et al. (2002) A genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes required for S phase progression in the presence of DNA damage. Proc Natl Acad Sci U S A 99(26):16934-9 |
SGD |
| DDC1/YPL194W | IEA: Inferred from Electronic Annotation with EBI:KW-0227 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| DEF1/YKL054C | IMP: Inferred from Mutant Phenotype Assigned on 2002-07-16 |
manually curated | Woudstra EC, et al. (2002) A Rad26-Def1 complex coordinates repair and RNA pol II proteolysis in response to DNA damage. Nature 415(6874):929-33 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0227 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| DIN7/YDR263C | IEA: Inferred from Electronic Annotation with EBI:KW-0227 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| DNA2/YHR164C | IEA: Inferred from Electronic Annotation with EBI:KW-0227 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| DNL4/YOR005C | IEA: Inferred from Electronic Annotation with EBI:KW-0227 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| DUN1/YDL101C | IEA: Inferred from Electronic Annotation with EBI:KW-0227 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
