GO term: response to osmotic stress 
Ontology: Biological Process (GO:0006970)
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
Synonyms: osmotic response; osmotic stress response
View Ontology:
(graph) | 
(text)
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
Synonyms: osmotic response; osmotic stress response
View Ontology:
(graph) | (text)
This table lists the methods used to annotate genes either directly to the term
response to osmotic stress (24 genes)
or to its variants containing one or more
qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | response to osmotic stress | 24 |
| High-throughput | none | none |
| Computational | none | none |
Links to Additional Annotations:
- View
annotations in multiple organisms using
- Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.
Annotation details for genes that have been directly annotated to the term
response to osmotic stress or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| response to osmotic stress 24 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| AGP2/YBR132C | IDA: Inferred from Direct Assay Assigned on 2002-09-19 |
manually curated | Lee J, et al. (2002) Carnitine uptake by AGP2 in yeast Saccharomyces cerevisiae is dependent on Hog1 MAP kinase pathway. Mol Cells 13(3):407-12 |
SGD |
| AIP1/YMR092C | TAS: Traceable Author Statement Assigned on 2001-01-18 |
manually curated | Pruyne D and Bretscher A (2000) Polarization of cell growth in yeast. J Cell Sci 113 ( Pt 4):571-85 |
SGD |
| ELM1/YKL048C | TAS: Traceable Author Statement Assigned on 2001-01-18 |
manually curated | Pruyne D and Bretscher A (2000) Polarization of cell growth in yeast. J Cell Sci 113 ( Pt 4):571-85 |
SGD |
| GRX5/YPL059W | IMP: Inferred from Mutant Phenotype Assigned on 2001-01-18 |
manually curated | Rodriguez-Manzaneque MT, et al. (1999) Grx5 glutaredoxin plays a central role in protection against protein oxidative damage in Saccharomyces cerevisiae. Mol Cell Biol 19(12):8180-90 |
SGD |
| HOR2/YER062C | IDA: Inferred from Direct Assay Assigned on 2001-01-18 |
manually curated | Norbeck J, et al. (1996) Purification and characterization of two isoenzymes of DL-glycerol-3-phosphatase from Saccharomyces cerevisiae. Identification of the corresponding GPP1 and GPP2 genes and evidence for osmotic regulation of Gpp2p expression by the osmosensing mitogen-activated protein kinase signal transduction pathway. J Biol Chem 271(23):13875-81 |
SGD |
| HSP82/YPL240C | IMP: Inferred from Mutant Phenotype Assigned on 2006-05-12 |
manually curated | Yang XX, et al. (2006) The molecular chaperone Hsp90 is required for high osmotic stress response in Saccharomyces cerevisiae. FEMS Yeast Res 6(2):195-204 |
SGD |
| IQG1/YPL242C | TAS: Traceable Author Statement Assigned on 2001-01-18 |
manually curated | Pruyne D and Bretscher A (2000) Polarization of cell growth in yeast. J Cell Sci 113 ( Pt 4):571-85 |
SGD |
| LTV1/YKL143W | IMP: Inferred from Mutant Phenotype Assigned on 2005-05-03 |
manually curated | Loar JW, et al. (2004) Genetic and biochemical interactions among Yar1, Ltv1 and Rps3 define novel links between environmental stress and ribosome biogenesis in Saccharomyces cerevisiae. Genetics 168(4):1877-89 |
SGD |
| MID2/YLR332W | IGI: Inferred from Genetic Interaction with SGD:PPZ1 Assigned on 2005-05-05 |
manually curated | Merchan S, et al. (2004) Response of the Saccharomyces cerevisiae Mpk1 mitogen-activated protein kinase pathway to increases in internal turgor pressure caused by loss of Ppz protein phosphatases. Eukaryot Cell 3(1):100-7 |
SGD |
| MSB2/YGR014W | IMP: Inferred from Mutant Phenotype Assigned on 2002-12-05 |
manually curated | O'Rourke SM and Herskowitz I (2002) A third osmosensing branch in Saccharomyces cerevisiae requires the Msb2 protein and functions in parallel with the Sho1 branch. Mol Cell Biol 22(13):4739-49 |
SGD |
| MYO3/YKL129C | TAS: Traceable Author Statement Assigned on 2001-01-18 |
manually curated | Pruyne D and Bretscher A (2000) Polarization of cell growth in yeast. J Cell Sci 113 ( Pt 4):571-85 |
SGD |
| MYO5/YMR109W | TAS: Traceable Author Statement Assigned on 2001-01-18 |
manually curated | Pruyne D and Bretscher A (2000) Polarization of cell growth in yeast. J Cell Sci 113 ( Pt 4):571-85 |
SGD |
| NHA1/YLR138W | IMP: Inferred from Mutant Phenotype Assigned on 2006-04-03 |
manually curated | Kinclova-Zimmermannova O and Sychrova H (2006) Functional study of the Nha1p C-terminus: involvement in cell response to changes in external osmolarity. Curr Genet 49(4):229-36 |
SGD |
| RHR2/YIL053W | TAS: Traceable Author Statement Assigned on 2002-09-11 |
manually curated | Remize F, et al. (2001) Glycerol export and glycerol-3-phosphate dehydrogenase, but not glycerol phosphatase, are rate limiting for glycerol production in Saccharomyces cerevisiae. Metab Eng 3(4):301-12 |
SGD |
| RRD1/YIL153W | IMP: Inferred from Mutant Phenotype Assigned on 2001-01-18 |
manually curated | Rempola B, et al. (2000) Functional analysis of RRD1 (YIL153w) and RRD2 (YPL152w), which encode two putative activators of the phosphotyrosyl phosphatase activity of PP2A in Saccharomyces cerevisiae. Mol Gen Genet 262(6):1081-92 |
SGD |
| RRD2/YPL152W | IGI: Inferred from Genetic Interaction, IMP: Inferred from Mutant Phenotype Assigned on 2001-01-18 |
manually curated | Rempola B, et al. (2000) Functional analysis of RRD1 (YIL153w) and RRD2 (YPL152w), which encode two putative activators of the phosphotyrosyl phosphatase activity of PP2A in Saccharomyces cerevisiae. Mol Gen Genet 262(6):1081-92 |
SGD |
| RVS161/YCR009C | IMP: Inferred from Mutant Phenotype Assigned on 2009-03-13 |
manually curated | Crouzet M, et al. (1991) Yeast mutant affected for viability upon nutrient starvation: characterization and cloning of the RVS161 gene. Yeast 7(7):727-43 |
SGD |
| SAC6/YDR129C | TAS: Traceable Author Statement Assigned on 2001-01-18 |
manually curated | Pruyne D and Bretscher A (2000) Polarization of cell growth in yeast. J Cell Sci 113 ( Pt 4):571-85 |
SGD |
| SKN7/YHR206W | TAS: Traceable Author Statement Assigned on 2002-07-26 |
manually curated | Li S, et al. (2002) The eukaryotic two-component histidine kinase Sln1p regulates OCH1 via the transcription factor, Skn7p. Mol Biol Cell 13(2):412-24 |
SGD |
| SLG1/YOR008C | IGI: Inferred from Genetic Interaction with SGD:PPZ1 Assigned on 2005-05-05 |
manually curated | Merchan S, et al. (2004) Response of the Saccharomyces cerevisiae Mpk1 mitogen-activated protein kinase pathway to increases in internal turgor pressure caused by loss of Ppz protein phosphatases. Eukaryot Cell 3(1):100-7 |
SGD |
| SSK2/YNR031C | IGI: Inferred from Genetic Interaction, IMP: Inferred from Mutant Phenotype Assigned on 2005-03-03 |
manually curated | Yuzyuk T and Amberg DC (2003) Actin recovery and bud emergence in osmotically stressed cells requires the conserved actin interacting mitogen-activated protein kinase kinase kinase Ssk2p/MTK1 and the scaffold protein Spa2p. Mol Biol Cell 14(7):3013-26 |
SGD |
| STO1/YMR125W | IMP: Inferred from Mutant Phenotype Assigned on 2011-12-01 |
manually curated | Garre E, et al. (2012) Yeast mRNA cap-binding protein Cbc1/Sto1 is necessary for the rapid reprogramming of translation after hyperosmotic shock. Mol Biol Cell 23(1):137-50 |
SGD |
| TIM18/YOR297C | IMP: Inferred from Mutant Phenotype Assigned on 2007-10-19 |
manually curated | Du L, et al. (2007) Tim18, a component of the mitochondrial translocator, mediates yeast cell death induced by arsenic. Biochemistry (Mosc) 72(8):843-7 |
SGD |
| YAR1/YPL239W | IMP: Inferred from Mutant Phenotype Assigned on 2005-05-03 |
manually curated | Loar JW, et al. (2004) Genetic and biochemical interactions among Yar1, Ltv1 and Rps3 define novel links between environmental stress and ribosome biogenesis in Saccharomyces cerevisiae. Genetics 168(4):1877-89 |
SGD |
