GO term: response to stress Help



Ontology: Biological Process (GO:0006950)

Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

Synonyms: response to abiotic stress; response to biotic stress

View Ontology: GO Tree Graph (graph) | Amigo (text)

Annotation Summary


This table lists the methods used to annotate genes either directly to the term response to stress (151 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method GO Term # Yeast Genes Annotated
Manually curated (download data) response to stress 48
High-throughput none none
Computational (download data) response to stress 124

Links to Additional Annotations:
Genes Annotated with this Term
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Annotation details for genes that have been directly annotated to the term response to stress or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

response to stress
     151 genes directly annotated to this term
Locus Evidence Annotation Method Reference Assigned By
AAD4/YDL243C IEA: Inferred from Electronic Annotation
with EBI:KW-0346
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
AHA1/YDR214W IMP: Inferred from Mutant Phenotype,
IPI: Inferred from Physical Interaction
with SGD:HSP82
Assigned on 2003-01-07
manually curated Panaretou B, et al.  (2002) Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1. Mol Cell 10(6):1307-18 SGD
IEA: Inferred from Electronic Annotation
with EBI:IPR013538
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0346
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
ARO2/YGL148W IEA: Inferred from Electronic Annotation
with EBI:KW-0346
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
ARO3/YDR035W IEA: Inferred from Electronic Annotation
with EBI:KW-0346
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
ARO4/YBR249C IEA: Inferred from Electronic Annotation
with EBI:KW-0346
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
ASG1/YIL130W IEA: Inferred from Electronic Annotation
with EBI:KW-0346
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
ATC1/YDR184C IGI: Inferred from Genetic Interaction
Assigned on 2003-04-15
manually curated Hemenway CS and Heitman J  (1999) Lic4, a nuclear phosphoprotein that cooperates with calcineurin to regulate cation homeostasis in Saccharomyces cerevisiae. Mol Gen Genet 261(2):388-401 SGD
ATH1/YPR026W IMP: Inferred from Mutant Phenotype
Assigned on 2001-01-18
manually curated Kim J, et al.  (1996) Disruption of the yeast ATH1 gene confers better survival after dehydration, freezing, and ethanol shock: potential commercial applications. Appl Environ Microbiol 62(5):1563-9 SGD
BSD2/YBR290W IEA: Inferred from Electronic Annotation
with EBI:KW-0346
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
CCH1/YGR217W IEA: Inferred from Electronic Annotation
with EBI:KW-0346
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
CPR7/YJR032W IGI: Inferred from Genetic Interaction,
IMP: Inferred from Mutant Phenotype
Assigned on 2003-01-22
manually curated Duina AA, et al.  (1998) Requirement for Hsp90 and a CyP-40-type cyclophilin in negative regulation of the heat shock response. J Biol Chem 273(30):18974-8 SGD
CTK1/YKL139W IEA: Inferred from Electronic Annotation
with EBI:KW-0346
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
DAK1/YML070W IMP: Inferred from Mutant Phenotype
Assigned on 2003-01-27
manually curated Molin M, et al.  (2003) Dihydroxyacetone kinases in Saccharomyces cerevisiae are involved in detoxification of dihydroxyacetone. J Biol Chem 278(3):1415-23 SGD
DAK2/YFL053W IMP: Inferred from Mutant Phenotype
Assigned on 2003-01-27
manually curated Molin M, et al.  (2003) Dihydroxyacetone kinases in Saccharomyces cerevisiae are involved in detoxification of dihydroxyacetone. J Biol Chem 278(3):1415-23 SGD
DAN1/YJR150C IEA: Inferred from Electronic Annotation
with EBI:IPR000992
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
DAN4/YJR151C IEA: Inferred from Electronic Annotation
with EBI:IPR000992
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
DDR2/YOL052C-A IDA: Inferred from Direct Assay
Assigned on 2001-01-18
manually curated Treger JM, et al.  (1998) Functional analysis of the stress response element and its role in the multistress response of Saccharomyces cerevisiae. Biochem Biophys Res Commun 243(1):13-9 SGD
IEA: Inferred from Electronic Annotation
with EBI:KW-0346
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
DDR48/YMR173W IEA: Inferred from Electronic Annotation
with EBI:KW-0346
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
DFM1/YDR411C IEA: Inferred from Electronic Annotation
with EBI:KW-0346
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
FMC1/YIL098C IEA: Inferred from Electronic Annotation
with EBI:KW-0346
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
FMP41/YNL168C IEA: Inferred from Electronic Annotation
with EBI:KW-0346
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
FMP43/YGR243W IEA: Inferred from Electronic Annotation
with EBI:KW-0346
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
FMP45/YDL222C IEA: Inferred from Electronic Annotation
with EBI:KW-0346
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
FRT1/YOR324C IMP: Inferred from Mutant Phenotype
Assigned on 2004-07-06
manually curated Heath VL, et al.  (2004) Hph1p and Hph2p, novel components of calcineurin-mediated stress responses in Saccharomyces cerevisiae. Eukaryot Cell 3(3):695-704 SGD
IEA: Inferred from Electronic Annotation
with EBI:IPR025752
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
FRT2/YAL028W IMP: Inferred from Mutant Phenotype
Assigned on 2004-07-06
manually curated Heath VL, et al.  (2004) Hph1p and Hph2p, novel components of calcineurin-mediated stress responses in Saccharomyces cerevisiae. Eukaryot Cell 3(3):695-704 SGD
IEA: Inferred from Electronic Annotation
with EBI:IPR025752
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
GCN2/YDR283C IEA: Inferred from Electronic Annotation
with EBI:KW-0346
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
GPD1/YDL022W IEA: Inferred from Electronic Annotation
with EBI:KW-0346
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
GRE1/YPL223C IEA: Inferred from Electronic Annotation
with EBI:KW-0346
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
GRE3/YHR104W IDA: Inferred from Direct Assay
Assigned on 2002-08-19
manually curated Aguilera J and Prieto JA  (2001) The Saccharomyces cerevisiae aldose reductase is implied in the metabolism of methylglyoxal in response to stress conditions. Curr Genet 39(5-6):273-83 SGD
IEA: Inferred from Electronic Annotation
with EBI:KW-0346
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
HAL1/YPR005C IEA: Inferred from Electronic Annotation
with EBI:KW-0346
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB