Ontology: Biological Process (GO:0006887)

Definition: A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. This is the process in which most molecules are secreted from eukaryotic cells.

Synonyms: nonselective vesicle exocytosis; vesicle exocytosis

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term exocytosis (43 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	exocytosis	40
High-throughput	none	none
Computational (download data)	exocytosis	17

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term exocytosis or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

exocytosis      43 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
SLA2/YNL243W	TAS: Traceable Author Statement Assigned on 2001-01-18	manually curated	Pruyne D and Bretscher A  (2000) Polarization of cell growth in yeast. J Cell Sci 113 ( Pt 4):571-85	SGD
SMY1/YKL079W	IGI: Inferred from Genetic Interaction Assigned on 2001-01-18	manually curated	Lillie SH and Brown SS  (1998) Smy1p, a kinesin-related protein that does not require microtubules. J Cell Biol 140(4):873-83	SGD
SNC1/YAL030W	IMP: Inferred from Mutant Phenotype Assigned on 2011-05-16	manually curated	Gerst JE  (1997) Conserved alpha-helical segments on yeast homologs of the synaptobrevin/VAMP family of v-SNAREs mediate exocytic function. J Biol Chem 272(26):16591-8	SGD
SNC2/YOR327C	IMP: Inferred from Mutant Phenotype Assigned on 2011-05-16	manually curated	Gerst JE  (1997) Conserved alpha-helical segments on yeast homologs of the synaptobrevin/VAMP family of v-SNAREs mediate exocytic function. J Biol Chem 272(26):16591-8	SGD
SPO14/YKR031C	IGI: Inferred from Genetic Interaction Assigned on 2003-03-05	manually curated	Rudge SA, et al.  (2001) SPO14 separation-of-function mutations define unique roles for phospholipase D in secretion and cellular differentiation in Saccharomyces cerevisiae. Genetics 158(4):1431-44	SGD
	IGI: Inferred from Genetic Interaction Assigned on 2003-03-05	manually curated	Li X, et al.  (2000) Identification of a novel family of nonclassic yeast phosphatidylinositol transfer proteins whose function modulates phospholipase D activity and Sec14p-independent cell growth. Mol Biol Cell 11(6):1989-2005	SGD
SRO7/YPR032W	IGI: Inferred from Genetic Interaction Assigned on 2003-01-22	manually curated	Lehman K, et al.  (1999) Yeast homologues of tomosyn and lethal giant larvae function in exocytosis and are associated with the plasma membrane SNARE, Sec9. J Cell Biol 146(1):125-40	SGD
	IEA: Inferred from Electronic Annotation with EBI:KW-0268 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
SRO77/YBL106C	IGI: Inferred from Genetic Interaction Assigned on 2003-01-22	manually curated	Lehman K, et al.  (1999) Yeast homologues of tomosyn and lethal giant larvae function in exocytosis and are associated with the plasma membrane SNARE, Sec9. J Cell Biol 146(1):125-40	SGD
	IEA: Inferred from Electronic Annotation with EBI:KW-0268 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
SWH1/YAR042W	IGI: Inferred from Genetic Interaction with SGD:OSH2, SGD:OSH3, SGD:KES1, SGD:HES1, SGD:OSH6, SGD:OSH7, SGD:RHO1 Assigned on 2006-11-30	manually curated	Kozminski KG, et al.  (2006) Homologues of oxysterol-binding proteins affect Cdc42p- and Rho1p-mediated cell polarization in Saccharomyces cerevisiae. Traffic 7(9):1224-42	SGD
SYT1/YPR095C	IGI: Inferred from Genetic Interaction with SGD:YPT31, SGD:YPT32 Assigned on 2008-08-01	manually curated	Jones S, et al.  (1999) Genetic interactions in yeast between Ypt GTPases and Arf guanine nucleotide exchangers. Genetics 152(4):1543-56	SGD
TPM1/YNL079C	TAS: Traceable Author Statement Assigned on 2001-01-18	manually curated	Pruyne D and Bretscher A  (2000) Polarization of cell growth in yeast. J Cell Sci 113 ( Pt 4):571-85	SGD
TPM2/YIL138C	TAS: Traceable Author Statement Assigned on 2001-01-18	manually curated	Pruyne D and Bretscher A  (2000) Polarization of cell growth in yeast. J Cell Sci 113 ( Pt 4):571-85	SGD
YPT31/YER031C	IMP: Inferred from Mutant Phenotype Assigned on 2002-06-24	manually curated	Jedd G, et al.  (1997) Two new Ypt GTPases are required for exit from the yeast trans-Golgi compartment. J Cell Biol 137(3):563-80	SGD
YPT32/YGL210W	IMP: Inferred from Mutant Phenotype Assigned on 2002-06-24	manually curated	Jedd G, et al.  (1997) Two new Ypt GTPases are required for exit from the yeast trans-Golgi compartment. J Cell Biol 137(3):563-80	SGD
	IEA: Inferred from Electronic Annotation with EBI:KW-0268 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB

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