GO term: exocytosis Help


Ontology: Biological Process (GO:0006887)

Definition: A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. This is the process whereby most molecules are secreted from eukaryotic cells.

Synonyms: nonselective vesicle exocytosis; vesicle exocytosis

Annotation Summary
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This table lists the methods used to annotate genes either directly to the term exocytosis (41 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method GO Term # Yeast Genes Annotated
Manually curated (download data) exocytosis 34
High-throughput none none
Computational (download data) exocytosis 16

Links to Additional Annotations:
Genes Annotated with this Term
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Annotation details for genes that have been directly annotated to the term exocytosis or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

Results: 1 - 30 of 41 records
   1  2 

exocytosis
     41 genes directly annotated to this term
Locus Evidence Annotation Method Reference Assigned By
ACT1/YFL039C TAS: Traceable Author Statement
Assigned on 2001-01-18 		manually curated Pruyne D and Bretscher A  (2000) Polarization of cell growth in yeast. J Cell Sci 113 ( Pt 4):571-85
SGD
CDC42/YLR229C IGI: Inferred from Genetic Interaction
Assigned on 2002-11-05 		manually curated Zhang X, et al.  (2001) Cdc42 interacts with the exocyst and regulates polarized secretion. J Biol Chem 276(50):46745-50
SGD
EXO70/YJL085W IGI: Inferred from Genetic Interaction
with SGD:SEC3
Assigned on 2008-09-04 		manually curated He B, et al.  (2007) Exo70 interacts with phospholipids and mediates the targeting of the exocyst to the plasma membrane. EMBO J 26(18):4053-65
SGD
IEA: Inferred from Electronic Annotation
with EBI:IPR004140
Last Updated 2009-11-20 		computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.
UniProtKB
IEA: Inferred from Electronic Annotation
with EBI:KW-0268
Last Updated 2009-11-20 		computational GOA curators  (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping.
UniProtKB
EXO84/YBR102C IGI: Inferred from Genetic Interaction,
IMP: Inferred from Mutant Phenotype,
IPI: Inferred from Physical Interaction
Assigned on 2004-07-30 		manually curated Guo W, et al.  (1999) Exo84p is an exocyst protein essential for secretion. J Biol Chem 274(33):23558-64
SGD
IEA: Inferred from Electronic Annotation
with EBI:KW-0268
Last Updated 2009-11-20 		computational GOA curators  (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping.
UniProtKB
GYP5/YPL249C IEA: Inferred from Electronic Annotation
with EBI:KW-0268
Last Updated 2009-11-20 		computational GOA curators  (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping.
UniProtKB
HES1/YOR237W IGI: Inferred from Genetic Interaction
with SGD:SWH1, SGD:OSH2, SGD:OSH7, SGD:OSH3, SGD:OSH6, SGD:KES1, SGD:RHO1
Assigned on 2006-11-30 		manually curated Kozminski KG, et al.  (2006) Homologues of oxysterol-binding proteins affect Cdc42p- and Rho1p-mediated cell polarization in Saccharomyces cerevisiae. Traffic 7(9):1224-42
SGD
KES1/YPL145C IGI: Inferred from Genetic Interaction
with SGD:SWH1, SGD:OSH2, SGD:SEC5, SGD:SEC3, SGD:SEC4, SGD:OSH7, SGD:OSH3, SGD:OSH6, SGD:MSB3, SGD:MSB4, SGD:HES1, SGD:RHO1
Assigned on 2006-11-30 		manually curated Kozminski KG, et al.  (2006) Homologues of oxysterol-binding proteins affect Cdc42p- and Rho1p-mediated cell polarization in Saccharomyces cerevisiae. Traffic 7(9):1224-42
SGD
KIN1/YDR122W IGI: Inferred from Genetic Interaction
with SGD:SEC1, SGD:SEC3, SGD:SEC4, SGD:SEC15, SGD:RHO3, SGD:SEC10, SGD:CDC42, SGD:SEC2,
IPI: Inferred from Physical Interaction
with SGD:SEC9, SGD:SRO7
Assigned on 2007-08-21 		manually curated Elbert M, et al.  (2005) The yeast par-1 homologs kin1 and kin2 show genetic and physical interactions with components of the exocytic machinery. Mol Biol Cell 16(2):532-49
SGD
IEA: Inferred from Electronic Annotation
with EBI:KW-0268
Last Updated 2009-11-20 		computational GOA curators  (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping.
UniProtKB
KIN2/YLR096W IGI: Inferred from Genetic Interaction
with SGD:SEC1, SGD:SEC3, SGD:SEC4, SGD:SEC15, SGD:RHO3, SGD:SEC10, SGD:CDC42, SGD:SEC2,
IPI: Inferred from Physical Interaction
with SGD:SEC9, SGD:SRO7
Assigned on 2005-02-16 		manually curated Elbert M, et al.  (2005) The yeast par-1 homologs kin1 and kin2 show genetic and physical interactions with components of the exocytic machinery. Mol Biol Cell 16(2):532-49
SGD
IEA: Inferred from Electronic Annotation
with EBI:KW-0268
Last Updated 2009-11-20 		computational GOA curators  (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping.
UniProtKB
MSB3/YNL293W TAS: Traceable Author Statement
Assigned on 2001-01-18 		manually curated Albert S and Gallwitz D  (1999) Two new members of a family of Ypt/Rab GTPase activating proteins. Promiscuity of substrate recognition. J Biol Chem 274(47):33186-9
SGD
MYO3/YKL129C TAS: Traceable Author Statement
Assigned on 2001-01-18 		manually curated Pruyne D and Bretscher A  (2000) Polarization of cell growth in yeast. J Cell Sci 113 ( Pt 4):571-85
SGD
MYO5/YMR109W TAS: Traceable Author Statement
Assigned on 2001-01-18 		manually curated Pruyne D and Bretscher A  (2000) Polarization of cell growth in yeast. J Cell Sci 113 ( Pt 4):571-85
SGD
OSH2/YDL019C IGI: Inferred from Genetic Interaction
with SGD:SWH1, SGD:SEC5, SGD:SEC3, SGD:SEC4, SGD:OSH7, SGD:OSH3, SGD:OSH6, SGD:MSB3, SGD:MSB4, SGD:HES1, SGD:KES1, SGD:RHO1
Assigned on 2006-11-30 		manually curated Kozminski KG, et al.  (2006) Homologues of oxysterol-binding proteins affect Cdc42p- and Rho1p-mediated cell polarization in Saccharomyces cerevisiae. Traffic 7(9):1224-42
SGD
OSH3/YHR073W IGI: Inferred from Genetic Interaction
with SGD:SWH1, SGD:OSH2, SGD:OSH7, SGD:OSH6, SGD:HES1, SGD:KES1
Assigned on 2006-11-30 		manually curated Kozminski KG, et al.  (2006) Homologues of oxysterol-binding proteins affect Cdc42p- and Rho1p-mediated cell polarization in Saccharomyces cerevisiae. Traffic 7(9):1224-42
SGD
OSH6/YKR003W IGI: Inferred from Genetic Interaction
with SGD:SWH1, SGD:OSH2, SGD:OSH7, SGD:OSH3, SGD:HES1, SGD:KES1, SGD:RHO1
Assigned on 2006-11-30 		manually curated Kozminski KG, et al.  (2006) Homologues of oxysterol-binding proteins affect Cdc42p- and Rho1p-mediated cell polarization in Saccharomyces cerevisiae. Traffic 7(9):1224-42
SGD
OSH7/YHR001W IGI: Inferred from Genetic Interaction
with SGD:SWH1, SGD:OSH2, SGD:OSH3, SGD:OSH6, SGD:HES1, SGD:KES1, SGD:RHO1
Assigned on 2006-11-30 		manually curated Kozminski KG, et al.  (2006) Homologues of oxysterol-binding proteins affect Cdc42p- and Rho1p-mediated cell polarization in Saccharomyces cerevisiae. Traffic 7(9):1224-42
SGD
PMR1/YGL167C IGI: Inferred from Genetic Interaction
with SGD:GDI1, SGD:YPT1, SGD:SEC15, SGD:SEC9, SGD:SEC6, SGD:SEC10, SGD:SEC13, SGD:SEC21
Assigned on 2008-08-01 		manually curated Antebi A and Fink GR  (1992) The yeast Ca(2+)-ATPase homologue, PMR1, is required for normal Golgi function and localizes in a novel Golgi-like distribution. Mol Biol Cell 3(6):633-54
SGD
RCY1/YJL204C IEA: Inferred from Electronic Annotation
with EBI:IPR009976
Last Updated 2009-11-20 		computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.
UniProtKB
RHO3/YIL118W TAS: Traceable Author Statement
Assigned on 2001-01-18 		manually curated Madden K and Snyder M  (1998) Cell polarity and morphogenesis in budding yeast. Annu Rev Microbiol 52():687-744
SGD
SEC1/YDR164C IMP: Inferred from Mutant Phenotype,
IPI: Inferred from Physical Interaction
Assigned on 2001-01-18 		manually curated Carr CM, et al.  (1999) Sec1p binds to SNARE complexes and concentrates at sites of secretion. J Cell Biol 146(2):333-44
SGD
SEC10/YLR166C IEA: Inferred from Electronic Annotation
with EBI:IPR009976
Last Updated 2009-11-20 		computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.
UniProtKB
IEA: Inferred from Electronic Annotation
with EBI:KW-0268
Last Updated 2009-11-20 		computational GOA curators  (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping.
UniProtKB
SEC15/YGL233W IEA: Inferred from Electronic Annotation
with EBI:KW-0268
Last Updated 2009-11-20 		computational GOA curators  (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping.
UniProtKB
SEC2/YNL272C IMP: Inferred from Mutant Phenotype
Assigned on 2002-07-29 		manually curated Ortiz D, et al.  (2002) Ypt32 recruits the Sec4p guanine nucleotide exchange factor, Sec2p, to secretory vesicles; evidence for a Rab cascade in yeast. J Cell Biol 157(6):1005-15
SGD
SEC3/YER008C IDA: Inferred from Direct Assay
Assigned on 2006-06-19 		manually curated VerPlank L and Li R  (2005) Cell cycle-regulated trafficking of Chs2 controls actomyosin ring stability during cytokinesis. Mol Biol Cell 16(5):2529-43
SGD
IGI: Inferred from Genetic Interaction
with SGD:EXO70
Assigned on 2008-09-04 		manually curated He B, et al.  (2007) Exo70 interacts with phospholipids and mediates the targeting of the exocyst to the plasma membrane. EMBO J 26(18):4053-65
SGD
IEA: Inferred from Electronic Annotation
with EBI:KW-0268
Last Updated 2009-11-20 		computational GOA curators  (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping.
UniProtKB
SEC4/YFL005W IDA: Inferred from Direct Assay
Assigned on 2006-06-19 		manually curated VerPlank L and Li R  (2005) Cell cycle-regulated trafficking of Chs2 controls actomyosin ring stability during cytokinesis. Mol Biol Cell 16(5):2529-43
SGD
IEA: Inferred from Electronic Annotation
with EBI:KW-0268
Last Updated 2009-11-20 		computational GOA curators  (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping.
UniProtKB
SEC5/YDR166C IEA: Inferred from Electronic Annotation
with EBI:KW-0268
Last Updated 2009-11-20 		computational GOA curators  (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping.
UniProtKB
SEC6/YIL068C IEA: Inferred from Electronic Annotation
with EBI:KW-0268
Last Updated 2009-11-20 		computational GOA curators  (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping.
UniProtKB
SEC8/YPR055W IEA: Inferred from Electronic Annotation
with EBI:KW-0268
Last Updated 2009-11-20 		computational GOA curators  (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping.
UniProtKB
SEM1/YDR363W-A IGI: Inferred from Genetic Interaction,
IPI: Inferred from Physical Interaction
Assigned on 2002-12-16 		manually curated Jantti J, et al.  (1999) SEM1, a homologue of the split hand/split foot malformation candidate gene Dss1, regulates exocytosis and pseudohyphal differentiation in yeast. Proc Natl Acad Sci U S A 96(3):909-14
SGD
SLA2/YNL243W TAS: Traceable Author Statement
Assigned on 2001-01-18 		manually curated Pruyne D and Bretscher A  (2000) Polarization of cell growth in yeast. J Cell Sci 113 ( Pt 4):571-85
SGD
Results: 1 - 30 of 41 records
   1  2 

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