GO term: proteolysis Help



Ontology: Biological Process (GO:0006508)

Definition: The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

Synonyms: peptidolysis; ATP-dependent proteolysis

View Ontology: GO Tree Graph (graph) | Amigo (text)

Annotation Summary


This table lists the methods used to annotate genes either directly to the term proteolysis (162 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method GO Term # Yeast Genes Annotated
Manually curated (download data) proteolysis 15
High-throughput none none
Computational (download data) proteolysis 156

Links to Additional Annotations:
Genes Annotated with this Term
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Annotation details for genes that have been directly annotated to the term proteolysis or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

proteolysis
     162 genes directly annotated to this term
Locus Evidence Annotation Method Reference Assigned By
PUP1/YOR157C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
PUP2/YGR253C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
PUP3/YER094C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
QCR2/YPR191W IEA: Inferred from Electronic Annotation
with EBI:IPR001431
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
RBD2/YPL246C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RIM11/YMR139W IGI: Inferred from Genetic Interaction
Assigned on 2002-10-09
manually curated Andoh T, et al.  (2000) Yeast glycogen synthase kinase 3 is involved in protein degradation in cooperation with Bul1, Bul2, and Rsp5. Mol Cell Biol 20(18):6712-20 SGD
RIM13/YMR154C IEA: Inferred from Electronic Annotation
with EBI:IPR001300
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RIM20/YOR275C IMP: Inferred from Mutant Phenotype
Assigned on 2002-10-28
manually curated Xu W and Mitchell AP  (2001) Yeast PalA/AIP1/Alix homolog Rim20p associates with a PEST-like region and is required for its proteolytic cleavage. J Bacteriol 183(23):6917-23 SGD
RPN12/YFR052W IEA: Inferred from Electronic Annotation
with EBI:IPR006746
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
RRI1/YDL216C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RRT12/YCR045C IEA: Inferred from Electronic Annotation
with EBI:IPR000209
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IBA: Inferred from Biological Aspect of Ancestor
with PANTHER:PTHR10795_AN631
Assigned on 2011-02-01
computational Gaudet P, et al.  (2011) Annotation inferences using phylogenetic trees. RefGenome
IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
SCL1/YGL011C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
SEC11/YIR022W IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
SNO4/YMR322C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
SOM1/YEL059C-A IGI: Inferred from Genetic Interaction,
ISS: Inferred from Sequence or structural Similarity
Assigned on 2002-09-27
manually curated Esser K, et al.  (1996) SOM 1, a small new gene required for mitochondrial inner membrane peptidase function in Saccharomyces cerevisiae. Mol Gen Genet 252(4):437-45 SGD
IGI: Inferred from Genetic Interaction,
IMP: Inferred from Mutant Phenotype,
IPI: Inferred from Physical Interaction
Assigned on 2002-09-27
manually curated Jan PS, et al.  (2000) Som1, a third component of the yeast mitochondrial inner membrane peptidase complex that contains Imp1 and Imp2. Mol Gen Genet 263(3):483-91 SGD
SSY5/YJL156C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
STE13/YOR219C IEA: Inferred from Electronic Annotation
with EBI:IPR002469, EBI:IPR001375
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
STE23/YLR389C IEA: Inferred from Electronic Annotation
with EBI:IPR001431
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
STE24/YJR117W IEA: Inferred from Electronic Annotation
with EBI:IPR001915
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
TMA108/YIL137C IEA: Inferred from Electronic Annotation
with EBI:IPR001930
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
TRE2/YOR256C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
UBP1/YDL122W IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
UBP10/YNL186W IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
UBP11/YKR098C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
UBP12/YJL197W IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
UBP13/YBL067C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
UBP14/YBR058C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
UBP15/YMR304W IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
UBP16/YPL072W IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
UBP2/YOR124C IEA: Inferred from Electronic Annotation
with EBI:KW-0645
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB