Ontology: Biological Process (GO:0006310)
Definition: Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
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(text)
Definition: Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
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This table lists the methods used to annotate genes either directly to the term
DNA recombination (93 genes)
or to its variants containing one or more
qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | DNA recombination | 14 |
| High-throughput | none | none |
| Computational (download data) | DNA recombination | 83 |
Links to Additional Annotations:
- View
annotations in multiple organisms using

- Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.
Annotation details for genes that have been directly annotated to the term
DNA recombination or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| DNA recombination 93 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| CDC9/YDL164C | IMP: Inferred from Mutant Phenotype Assigned on 2001-01-18 |
manually curated | Zou H and Rothstein R (1997) Holliday junctions accumulate in replication mutants via a RecA homolog-independent mechanism. Cell 90(1):87-96 | SGD |
| IEA: Inferred from Electronic Annotation with EBI:IPR000977, EBI:IPR012308, EBI:IPR012309, EBI:IPR012310 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro | |
| IEA: Inferred from Electronic Annotation with EBI:KW-0233 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| DNL4/YOR005C | IEA: Inferred from Electronic Annotation with EBI:IPR012308, EBI:IPR012310, EBI:IPR000977 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0233 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| ENS2 | IMP: Inferred from Mutant Phenotype Assigned on 2003-03-04 |
manually curated | Nakagawa K, et al. (1992) An endonuclease with multiple cutting sites, Endo.SceI, initiates genetic recombination at its cutting site in yeast mitochondria. EMBO J 11(7):2707-15 | SGD |
| FLP1/R0010W | IEA: Inferred from Electronic Annotation with EBI:IPR013762 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0233 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| FOB1/YDR110W | IMP: Inferred from Mutant Phenotype Assigned on 2001-01-18 |
manually curated | Kobayashi T and Horiuchi T (1996) A yeast gene product, Fob1 protein, required for both replication fork blocking and recombinational hotspot activities. Genes Cells 1(5):465-74 | SGD |
| HED1/YDR014W-A | IEA: Inferred from Electronic Annotation with EBI:KW-0233 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| HOP2/YGL033W | IEA: Inferred from Electronic Annotation with EBI:KW-0233 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| HPR1/YDR138W | IMP: Inferred from Mutant Phenotype Assigned on 2003-02-21 |
manually curated | Chavez S, et al. (2000) A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae. EMBO J 19(21):5824-34 | SGD |
| IMP: Inferred from Mutant Phenotype Assigned on 2001-01-18 |
manually curated | Aguilera A and Klein HL (1988) Genetic control of intrachromosomal recombination in Saccharomyces cerevisiae. I. Isolation and genetic characterization of hyper-recombination mutations. Genetics 119(4):779-90 | SGD | |
| KRE29/YER038C | IEA: Inferred from Electronic Annotation with EBI:KW-0233 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| LIF1/YGL090W | IEA: Inferred from Electronic Annotation with EBI:IPR014751 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| MEC1/YBR136W | IMP: Inferred from Mutant Phenotype Assigned on 2001-01-18 |
manually curated | Grushcow JM, et al. (1999) Saccharomyces cerevisiae checkpoint genes MEC1, RAD17 and RAD24 are required for normal meiotic recombination partner choice. Genetics 153(2):607-20 | SGD |
| MEI4/YER044C-A | IEA: Inferred from Electronic Annotation with EBI:KW-0233 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| MFT1/YML062C | IMP: Inferred from Mutant Phenotype Assigned on 2003-02-21 |
manually curated | Chavez S, et al. (2000) A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae. EMBO J 19(21):5824-34 | SGD |
| IEA: Inferred from Electronic Annotation with EBI:IPR027186 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro | |
| MHR1/YDR296W | IMP: Inferred from Mutant Phenotype Assigned on 2009-09-16 |
manually curated | Ling F and Shibata T (2002) Recombination-dependent mtDNA partitioning: in vivo role of Mhr1p to promote pairing of homologous DNA. EMBO J 21(17):4730-40 | SGD |
| MMS21/YEL019C | IEA: Inferred from Electronic Annotation with EBI:KW-0233 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| MMS4/YBR098W | IEA: Inferred from Electronic Annotation with EBI:KW-0233 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| MND1/YGL183C | IEA: Inferred from Electronic Annotation with EBI:KW-0233 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| MSC3/YLR219W | IEA: Inferred from Electronic Annotation with EBI:KW-0233 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| MSC6/YOR354C | IEA: Inferred from Electronic Annotation with EBI:KW-0233 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| MSH2/YOL090W | IMP: Inferred from Mutant Phenotype Assigned on 2005-07-14 |
manually curated | Langston LD and Symington LS (2005) Opposing roles for DNA structure-specific proteins Rad1, Msh2, Msh3, and Sgs1 in yeast gene targeting. EMBO J 24(12):2214-23 | SGD |
| MSH3/YCR092C | IMP: Inferred from Mutant Phenotype Assigned on 2005-07-14 |
manually curated | Langston LD and Symington LS (2005) Opposing roles for DNA structure-specific proteins Rad1, Msh2, Msh3, and Sgs1 in yeast gene targeting. EMBO J 24(12):2214-23 | SGD |
| MUS81/YDR386W | IEA: Inferred from Electronic Annotation with EBI:KW-0233 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| NSE1/YLR007W | IEA: Inferred from Electronic Annotation with EBI:KW-0233 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| NSE3/YDR288W | IEA: Inferred from Electronic Annotation with EBI:KW-0233 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| NSE4/YDL105W | IEA: Inferred from Electronic Annotation with EBI:KW-0233 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| NSE5/YML023C | IEA: Inferred from Electronic Annotation with EBI:KW-0233 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| NUC1/YJL208C | IMP: Inferred from Mutant Phenotype Assigned on 2001-01-18 |
manually curated | Zassenhaus HP and Denniger G (1994) Analysis of the role of the NUC1 endo/exonuclease in yeast mitochondrial DNA recombination. Curr Genet 25(2):142-9 | SGD |
| PIF1/YML061C | IMP: Inferred from Mutant Phenotype Assigned on 2001-01-18 |
manually curated | Lahaye A, et al. (1991) PIF1: a DNA helicase in yeast mitochondria. EMBO J 10(4):997-1007 | SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0233 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| RAD51/YER095W | IEA: Inferred from Electronic Annotation with EBI:KW-0233 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| RAD52/YML032C | IEA: Inferred from Electronic Annotation with EBI:IPR004585, EBI:IPR007232 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0233 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |



