GO term: DNA recombination Help



Ontology: Biological Process (GO:0006310)

Definition: Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.

View Ontology: GO Tree Graph (graph) | Amigo (text)

Annotation Summary


This table lists the methods used to annotate genes either directly to the term DNA recombination (93 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method GO Term # Yeast Genes Annotated
Manually curated (download data) DNA recombination 14
High-throughput none none
Computational (download data) DNA recombination 83

Links to Additional Annotations:
Genes Annotated with this Term
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Annotation details for genes that have been directly annotated to the term DNA recombination or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

DNA recombination
     93 genes directly annotated to this term
Locus Evidence Annotation Method Reference Assigned By
CDC9/YDL164C IMP: Inferred from Mutant Phenotype
Assigned on 2001-01-18
manually curated Zou H and Rothstein R  (1997) Holliday junctions accumulate in replication mutants via a RecA homolog-independent mechanism. Cell 90(1):87-96 SGD
IEA: Inferred from Electronic Annotation
with EBI:IPR000977, EBI:IPR012308, EBI:IPR012309, EBI:IPR012310
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0233
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
DNL4/YOR005C IEA: Inferred from Electronic Annotation
with EBI:IPR012308, EBI:IPR012310, EBI:IPR000977
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0233
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
ENS2 IMP: Inferred from Mutant Phenotype
Assigned on 2003-03-04
manually curated Nakagawa K, et al.  (1992) An endonuclease with multiple cutting sites, Endo.SceI, initiates genetic recombination at its cutting site in yeast mitochondria. EMBO J 11(7):2707-15 SGD
FLP1/R0010W IEA: Inferred from Electronic Annotation
with EBI:IPR013762
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0233
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
FOB1/YDR110W IMP: Inferred from Mutant Phenotype
Assigned on 2001-01-18
manually curated Kobayashi T and Horiuchi T  (1996) A yeast gene product, Fob1 protein, required for both replication fork blocking and recombinational hotspot activities. Genes Cells 1(5):465-74 SGD
HED1/YDR014W-A IEA: Inferred from Electronic Annotation
with EBI:KW-0233
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
HOP2/YGL033W IEA: Inferred from Electronic Annotation
with EBI:KW-0233
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
HPR1/YDR138W IMP: Inferred from Mutant Phenotype
Assigned on 2003-02-21
manually curated Chavez S, et al.  (2000) A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae. EMBO J 19(21):5824-34 SGD
IMP: Inferred from Mutant Phenotype
Assigned on 2001-01-18
manually curated Aguilera A and Klein HL  (1988) Genetic control of intrachromosomal recombination in Saccharomyces cerevisiae. I. Isolation and genetic characterization of hyper-recombination mutations. Genetics 119(4):779-90 SGD
KRE29/YER038C IEA: Inferred from Electronic Annotation
with EBI:KW-0233
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
LIF1/YGL090W IEA: Inferred from Electronic Annotation
with EBI:IPR014751
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
MEC1/YBR136W IMP: Inferred from Mutant Phenotype
Assigned on 2001-01-18
manually curated Grushcow JM, et al.  (1999) Saccharomyces cerevisiae checkpoint genes MEC1, RAD17 and RAD24 are required for normal meiotic recombination partner choice. Genetics 153(2):607-20 SGD
MEI4/YER044C-A IEA: Inferred from Electronic Annotation
with EBI:KW-0233
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
MFT1/YML062C IMP: Inferred from Mutant Phenotype
Assigned on 2003-02-21
manually curated Chavez S, et al.  (2000) A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae. EMBO J 19(21):5824-34 SGD
IEA: Inferred from Electronic Annotation
with EBI:IPR027186
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
MHR1/YDR296W IMP: Inferred from Mutant Phenotype
Assigned on 2009-09-16
manually curated Ling F and Shibata T  (2002) Recombination-dependent mtDNA partitioning: in vivo role of Mhr1p to promote pairing of homologous DNA. EMBO J 21(17):4730-40 SGD
MMS21/YEL019C IEA: Inferred from Electronic Annotation
with EBI:KW-0233
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
MMS4/YBR098W IEA: Inferred from Electronic Annotation
with EBI:KW-0233
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
MND1/YGL183C IEA: Inferred from Electronic Annotation
with EBI:KW-0233
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
MSC3/YLR219W IEA: Inferred from Electronic Annotation
with EBI:KW-0233
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
MSC6/YOR354C IEA: Inferred from Electronic Annotation
with EBI:KW-0233
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
MSH2/YOL090W IMP: Inferred from Mutant Phenotype
Assigned on 2005-07-14
manually curated Langston LD and Symington LS  (2005) Opposing roles for DNA structure-specific proteins Rad1, Msh2, Msh3, and Sgs1 in yeast gene targeting. EMBO J 24(12):2214-23 SGD
MSH3/YCR092C IMP: Inferred from Mutant Phenotype
Assigned on 2005-07-14
manually curated Langston LD and Symington LS  (2005) Opposing roles for DNA structure-specific proteins Rad1, Msh2, Msh3, and Sgs1 in yeast gene targeting. EMBO J 24(12):2214-23 SGD
MUS81/YDR386W IEA: Inferred from Electronic Annotation
with EBI:KW-0233
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
NSE1/YLR007W IEA: Inferred from Electronic Annotation
with EBI:KW-0233
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
NSE3/YDR288W IEA: Inferred from Electronic Annotation
with EBI:KW-0233
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
NSE4/YDL105W IEA: Inferred from Electronic Annotation
with EBI:KW-0233
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
NSE5/YML023C IEA: Inferred from Electronic Annotation
with EBI:KW-0233
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
NUC1/YJL208C IMP: Inferred from Mutant Phenotype
Assigned on 2001-01-18
manually curated Zassenhaus HP and Denniger G  (1994) Analysis of the role of the NUC1 endo/exonuclease in yeast mitochondrial DNA recombination. Curr Genet 25(2):142-9 SGD
PIF1/YML061C IMP: Inferred from Mutant Phenotype
Assigned on 2001-01-18
manually curated Lahaye A, et al.  (1991) PIF1: a DNA helicase in yeast mitochondria. EMBO J 10(4):997-1007 SGD
IEA: Inferred from Electronic Annotation
with EBI:KW-0233
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RAD51/YER095W IEA: Inferred from Electronic Annotation
with EBI:KW-0233
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RAD52/YML032C IEA: Inferred from Electronic Annotation
with EBI:IPR004585, EBI:IPR007232
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0233
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB