GO term: DNA repair 
Ontology: Biological Process (GO:0006281)
Definition: The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
View Ontology:
(graph) | 
(text)
Definition: The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
View Ontology:
(graph) | (text)
This table lists the methods used to annotate genes either directly to the term
DNA repair (188 genes)
or to its variants containing one or more
qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | DNA repair | 64 |
| High-throughput (download data) | DNA repair | 2 |
| Computational (download data) | DNA repair | 166 |
Links to Additional Annotations:
- View
annotations in multiple organisms using
- Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.
Annotation details for genes that have been directly annotated to the term
DNA repair or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| DNA repair 188 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| WSS1/YHR134W | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| XRS2/YDR369C | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| YAF9/YNL107W | IDA: Inferred from Direct Assay Assigned on 2007-01-03 |
manually curated | Utley RT, et al. (2005) Regulation of NuA4 histone acetyltransferase activity in transcription and DNA repair by phosphorylation of histone H4. Mol Cell Biol 25(18):8179-90 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| YEN1/YER041W | IGI: Inferred from Genetic Interaction with SGD:MUS81 Assigned on 2010-02-03 |
manually curated | Blanco MG, et al. (2010) Functional overlap between the structure-specific nucleases Yen1 and Mus81-Mms4 for DNA-damage repair in S. cerevisiae. DNA Repair (Amst) 9(4):394-402 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:IPR006084, EBI:IPR006085 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro | |
| IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| YKU70/YMR284W | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| YKU80/YMR106C | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| YNG2/YHR090C | IDA: Inferred from Direct Assay Assigned on 2007-01-03 |
manually curated | Utley RT, et al. (2005) Regulation of NuA4 histone acetyltransferase activity in transcription and DNA repair by phosphorylation of histone H4. Mol Cell Biol 25(18):8179-90 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| YNK1/YKL067W | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
