GO term: DNA repair 
Ontology: Biological Process (GO:0006281)
Definition: The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
View Ontology:
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(text)
Definition: The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
View Ontology:
(graph) | (text)
This table lists the methods used to annotate genes either directly to the term
DNA repair (188 genes)
or to its variants containing one or more
qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | DNA repair | 65 |
| High-throughput (download data) | DNA repair | 2 |
| Computational (download data) | DNA repair | 166 |
Links to Additional Annotations:
- View
annotations in multiple organisms using
- Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.
Annotation details for genes that have been directly annotated to the term
DNA repair or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| DNA repair 188 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| RAD57/YDR004W | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| RAD59/YDL059C | IEA: Inferred from Electronic Annotation with EBI:IPR007232 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| RAD6/YGL058W | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| RAD7/YJR052W | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| RAD9/YDR217C | IGI: Inferred from Genetic Interaction, IMP: Inferred from Mutant Phenotype Assigned on 2001-01-18 |
manually curated | Schiestl RH, et al. (1989) Cloning and sequence analysis of the Saccharomyces cerevisiae RAD9 gene and further evidence that its product is required for cell cycle arrest induced by DNA damage. Mol Cell Biol 9(5):1882-96 |
SGD |
| IGI: Inferred from Genetic Interaction with SGD:TOF1, SGD:CSM3, SGD:MRC1 Assigned on 2009-07-13 |
manually curated | Redon C, et al. (2006) Genetic analysis of Saccharomyces cerevisiae H2A serine 129 mutant suggests a functional relationship between H2A and the sister-chromatid cohesion partners Csm3-Tof1 for the repair of topoisomerase I-induced DNA damage. Genetics 172(1):67-76 |
SGD | |
| RDH54/YBR073W | IMP: Inferred from Mutant Phenotype Assigned on 2013-06-03 |
manually curated | Chi P, et al. (2006) Yeast recombination factor Rdh54 functionally interacts with the Rad51 recombinase and catalyzes Rad51 removal from DNA. J Biol Chem 281(36):26268-79 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| REV1/YOR346W | IEA: Inferred from Electronic Annotation with EBI:IPR012112, EBI:IPR017961, EBI:IPR017963, EBI:IPR001126 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB | |
| REV3/YPL167C | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| REV7/YIL139C | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| RFA1/YAR007C | IMP: Inferred from Mutant Phenotype Assigned on 2007-09-18 |
manually curated | Longhese MP, et al. (1994) Replication factor A is required in vivo for DNA replication, repair, and recombination. Mol Cell Biol 14(12):7884-90 |
SGD |
| RFA2/YNL312W | IMP: Inferred from Mutant Phenotype Assigned on 2007-09-18 |
manually curated | Maniar HS, et al. (1997) Roles of replication protein-A subunits 2 and 3 in DNA replication fork movement in Saccharomyces cerevisiae. Genetics 145(4):891-902 |
SGD |
| RFA3/YJL173C | IMP: Inferred from Mutant Phenotype Assigned on 2007-09-18 |
manually curated | Maniar HS, et al. (1997) Roles of replication protein-A subunits 2 and 3 in DNA replication fork movement in Saccharomyces cerevisiae. Genetics 145(4):891-902 |
SGD |
| RFC1/YOR217W | IMP: Inferred from Mutant Phenotype Assigned on 2003-02-05 |
manually curated | McAlear MA, et al. (1996) The large subunit of replication factor C (Rfc1p/Cdc44p) is required for DNA replication and DNA repair in Saccharomyces cerevisiae. Genetics 142(1):65-78 |
SGD |
| RPB4/YJL140W | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| RPB9/YGL070C | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| RPL40A/YIL148W | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| RPL40B/YKR094C | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| RPS31/YLR167W | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| RRD1/YIL153W | IMP: Inferred from Mutant Phenotype Assigned on 2008-05-13 |
manually curated | Ramotar D, et al. (1998) A yeast homologue of the human phosphotyrosyl phosphatase activator PTPA is implicated in protection against oxidative DNA damage induced by the model carcinogen 4-nitroquinoline 1-oxide. J Biol Chem 273(34):21489-96 |
SGD |
| IMP: Inferred from Mutant Phenotype Assigned on 2005-03-09 |
manually curated | Douville J, et al. (2004) The yeast phosphotyrosyl phosphatase activator protein, yPtpa1/Rrd1, interacts with Sit4 phosphatase to mediate resistance to 4-nitroquinoline-1-oxide and UVA. Curr Genet 46(2):72-81 |
SGD | |
| RRM3/YHR031C | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| RTT109/YLL002W | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| RVB1/YDR190C | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| RVB2/YPL235W | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| SAE2/YGL175C | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| SAE3/YHR079C-A | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| SAW1/YAL027W | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| SCC2/YDR180W | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| SGS1/YMR190C | IEA: Inferred from Electronic Annotation with EBI:IPR018982 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
InterPro |
| SHU1/YHL006C | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| SHU2/YDR078C | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. |
UniProtKB |
