Ontology: Biological Process (GO:0006281)
Definition: The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
View Ontology:
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Definition: The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
View Ontology:
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This table lists the methods used to annotate genes either directly to the term
DNA repair (188 genes)
or to its variants containing one or more
qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | DNA repair | 65 |
| High-throughput (download data) | DNA repair | 2 |
| Computational (download data) | DNA repair | 166 |
Links to Additional Annotations:
- View
annotations in multiple organisms using

- Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.
Annotation details for genes that have been directly annotated to the term
DNA repair or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| DNA repair 188 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| POB3/YML069W | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| POL30/YBR088C | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| POL4/YCR014C | IEA: Inferred from Electronic Annotation with EBI:IPR002008 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| PRP19/YLL036C | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| PSO2/YMR137C | IMP: Inferred from Mutant Phenotype Assigned on 2002-11-12 |
manually curated | Richter D, et al. (1992) Molecular structure of the DNA cross-link repair gene SNM1 (PSO2) of the yeast Saccharomyces cerevisiae. Mol Gen Genet 231(2):194-200 | SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| PSY3/YLR376C | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| RAD1/YPL022W | IEA: Inferred from Electronic Annotation with EBI:IPR006167 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| RAD10/YML095C | IEA: Inferred from Electronic Annotation with EBI:IPR004579 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| RAD14/YMR201C | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| RAD16/YBR114W | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| RAD17/YOR368W | IEA: Inferred from Electronic Annotation with EBI:IPR003021 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| RAD18/YCR066W | IEA: Inferred from Electronic Annotation with EBI:IPR004580 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| RAD2/YGR258C | IEA: Inferred from Electronic Annotation with EBI:IPR006084, EBI:IPR006085 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| RAD23/YEL037C | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| RAD24/YER173W | IEA: Inferred from Electronic Annotation with EBI:IPR004582, EBI:IPR018324 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| RAD26/YJR035W | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| RAD27/YKL113C | IEA: Inferred from Electronic Annotation with EBI:IPR006084, EBI:IPR006085 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| RAD28/YDR030C | IGI: Inferred from Genetic Interaction with SGD:RAD7, SGD:RAD16 Assigned on 2008-03-10 |
manually curated | Bhatia PK, et al. (1996) Molecular cloning and characterization of Saccharomyces cerevisiae RAD28, the yeast homolog of the human Cockayne syndrome A (CSA) gene. J Bacteriol 178(20):5977-88 | SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| RAD3/YER171W | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| RAD30/YDR419W | IEA: Inferred from Electronic Annotation with EBI:IPR001126, EBI:IPR017961, EBI:IPR017963 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| RAD33/YML011C | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| RAD34/YDR314C | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| RAD4/YER162C | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| RAD5/YLR032W | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| RAD50/YNL250W | IEA: Inferred from Electronic Annotation with EBI:IPR007517, EBI:IPR004584 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| RAD51/YER095W | IEA: Inferred from Electronic Annotation with EBI:IPR003583, EBI:IPR011941 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| RAD52/YML032C | IEA: Inferred from Electronic Annotation with EBI:IPR004585, EBI:IPR007232 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| RAD53/YPL153C | IMP: Inferred from Mutant Phenotype Assigned on 2001-11-01 |
manually curated | Zheng P, et al. (1993) SPK1 is an essential S-phase-specific gene of Saccharomyces cerevisiae that encodes a nuclear serine/threonine/tyrosine kinase. Mol Cell Biol 13(9):5829-42 | SGD |
| IEA: Inferred from Electronic Annotation with EBI:IPR016256 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro | |
| RAD54/YGL163C | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| RAD55/YDR076W | IEA: Inferred from Electronic Annotation with EBI:KW-0234 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |



