GO term: DNA repair Help



Ontology: Biological Process (GO:0006281)

Definition: The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.

View Ontology: GO Tree Graph (graph) | Amigo (text)

Annotation Summary


This table lists the methods used to annotate genes either directly to the term DNA repair (188 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method GO Term # Yeast Genes Annotated
Manually curated (download data) DNA repair 65
High-throughput (download data) DNA repair 2
Computational (download data) DNA repair 166

Links to Additional Annotations:
Genes Annotated with this Term
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Annotation details for genes that have been directly annotated to the term DNA repair or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

DNA repair
     188 genes directly annotated to this term
Locus Evidence Annotation Method Reference Assigned By
POB3/YML069W IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
POL30/YBR088C IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
POL4/YCR014C IEA: Inferred from Electronic Annotation
with EBI:IPR002008
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
PRP19/YLL036C IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
PSO2/YMR137C IMP: Inferred from Mutant Phenotype
Assigned on 2002-11-12
manually curated Richter D, et al.  (1992) Molecular structure of the DNA cross-link repair gene SNM1 (PSO2) of the yeast Saccharomyces cerevisiae. Mol Gen Genet 231(2):194-200 SGD
IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
PSY3/YLR376C IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RAD1/YPL022W IEA: Inferred from Electronic Annotation
with EBI:IPR006167
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RAD10/YML095C IEA: Inferred from Electronic Annotation
with EBI:IPR004579
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RAD14/YMR201C IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RAD16/YBR114W IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RAD17/YOR368W IEA: Inferred from Electronic Annotation
with EBI:IPR003021
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RAD18/YCR066W IEA: Inferred from Electronic Annotation
with EBI:IPR004580
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RAD2/YGR258C IEA: Inferred from Electronic Annotation
with EBI:IPR006084, EBI:IPR006085
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RAD23/YEL037C IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RAD24/YER173W IEA: Inferred from Electronic Annotation
with EBI:IPR004582, EBI:IPR018324
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RAD26/YJR035W IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RAD27/YKL113C IEA: Inferred from Electronic Annotation
with EBI:IPR006084, EBI:IPR006085
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RAD28/YDR030C IGI: Inferred from Genetic Interaction
with SGD:RAD7, SGD:RAD16
Assigned on 2008-03-10
manually curated Bhatia PK, et al.  (1996) Molecular cloning and characterization of Saccharomyces cerevisiae RAD28, the yeast homolog of the human Cockayne syndrome A (CSA) gene. J Bacteriol 178(20):5977-88 SGD
IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RAD3/YER171W IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RAD30/YDR419W IEA: Inferred from Electronic Annotation
with EBI:IPR001126, EBI:IPR017961, EBI:IPR017963
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RAD33/YML011C IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RAD34/YDR314C IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RAD4/YER162C IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RAD5/YLR032W IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RAD50/YNL250W IEA: Inferred from Electronic Annotation
with EBI:IPR007517, EBI:IPR004584
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RAD51/YER095W IEA: Inferred from Electronic Annotation
with EBI:IPR003583, EBI:IPR011941
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RAD52/YML032C IEA: Inferred from Electronic Annotation
with EBI:IPR004585, EBI:IPR007232
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RAD53/YPL153C IMP: Inferred from Mutant Phenotype
Assigned on 2001-11-01
manually curated Zheng P, et al.  (1993) SPK1 is an essential S-phase-specific gene of Saccharomyces cerevisiae that encodes a nuclear serine/threonine/tyrosine kinase. Mol Cell Biol 13(9):5829-42 SGD
IEA: Inferred from Electronic Annotation
with EBI:IPR016256
Last Updated 2013-03-02
computational DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms. InterPro
RAD54/YGL163C IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB
RAD55/YDR076W IEA: Inferred from Electronic Annotation
with EBI:KW-0234
Last Updated 2013-03-02
computational UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. UniProtKB