Ontology: Biological Process (GO:0006264)

Definition: The process in which new strands of DNA are synthesized in the mitochondrion.

Synonyms: mitochondrial DNA synthesis; mtDNA replication; mtDNA synthesis; replication of mitochondrial DNA

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term mitochondrial DNA replication (3 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	mitochondrial DNA replication	3
High-throughput	none	none
Computational	none	none

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term mitochondrial DNA replication or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

mitochondrial DNA replication      3 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
MIP1/YOR330C	IMP: Inferred from Mutant Phenotype Assigned on 2012-03-09	manually curated	Foury F  (1989) Cloning and sequencing of the nuclear gene MIP1 encoding the catalytic subunit of the yeast mitochondrial DNA polymerase. J Biol Chem 264(34):20552-60	SGD
	IDA: Inferred from Direct Assay Assigned on 2005-02-07	manually curated	Germaniuk A, et al.  (2002) A bichaperone (Hsp70-Hsp78) system restores mitochondrial DNA synthesis following thermal inactivation of Mip1p polymerase. J Biol Chem 277(31):27801-8	SGD
RIM1/YCR028C-A	ISS: Inferred from Sequence or structural Similarity with GenBank/EMBL/DDBJ:AAA24649.1 Assigned on 2007-11-14	manually curated	Van Dyck E, et al.  (1992) A single-stranded DNA binding protein required for mitochondrial DNA replication in S. cerevisiae is homologous to E. coli SSB. EMBO J 11(9):3421-30	SGD
SUV3/YPL029W	IMP: Inferred from Mutant Phenotype Assigned on 2011-11-16	manually curated	Guo XE, et al.  (2011) Uncoupling the roles of the SUV3 helicase in maintenance of mitochondrial genome stability and RNA degradation. J Biol Chem 286(44):38783-94	SGD

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