Ontology: Biological Process (GO:0005992)

Definition: The chemical reactions and pathways resulting in the formation of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.

Synonyms: mycose biosynthesis; mycose biosynthetic process; mykose biosynthesis; mykose biosynthetic process; trehalose anabolism; trehalose biosynthesis; trehalose formation; trehalose synthesis

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term trehalose biosynthetic process (7 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	trehalose biosynthetic process	7
High-throughput	none	none
Computational (download data)	trehalose biosynthetic process	4

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term trehalose biosynthetic process or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

trehalose biosynthetic process      7 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
PGM1/YKL127W	IGI: Inferred from Genetic Interaction with SGD:PGM2 Assigned on 2007-10-12	manually curated	Daran JM, et al.  (1997) Physiological and morphological effects of genetic alterations leading to a reduced synthesis of UDP-glucose in Saccharomyces cerevisiae. FEMS Microbiol Lett 153(1):89-96	SGD
PGM2/YMR105C	IGI: Inferred from Genetic Interaction with SGD:PGM1 Assigned on 2007-10-12	manually curated	Daran JM, et al.  (1997) Physiological and morphological effects of genetic alterations leading to a reduced synthesis of UDP-glucose in Saccharomyces cerevisiae. FEMS Microbiol Lett 153(1):89-96	SGD
TPS1/YBR126C	IDA: Inferred from Direct Assay, IMP: Inferred from Mutant Phenotype Assigned on 2005-08-04	manually curated	Bell W, et al.  (1992) Characterization of the 56-kDa subunit of yeast trehalose-6-phosphate synthase and cloning of its gene reveal its identity with the product of CIF1, a regulator of carbon catabolite inactivation. Eur J Biochem 209(3):951-9	SGD
	IEA: Inferred from Electronic Annotation with EBI:IPR001830, EBI:IPR012766 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
TPS2/YDR074W	IMP: Inferred from Mutant Phenotype Assigned on 2005-07-13	manually curated	De Virgilio C, et al.  (1993) Disruption of TPS2, the gene encoding the 100-kDa subunit of the trehalose-6-phosphate synthase/phosphatase complex in Saccharomyces cerevisiae, causes accumulation of trehalose-6-phosphate and loss of trehalose-6-phosphate phosphatase activity. Eur J Biochem 212(2):315-23	SGD
	IMP: Inferred from Mutant Phenotype Assigned on 2005-07-13	manually curated	Sur IP, et al.  (1994) Analysis of PFK3--a gene involved in particulate phosphofructokinase synthesis reveals additional functions of TPS2 in Saccharomyces cerevisiae. Yeast 10(2):199-209	SGD
	IEA: Inferred from Electronic Annotation with EBI:IPR003337, EBI:IPR001830 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
TPS3/YMR261C	IGI: Inferred from Genetic Interaction, IMP: Inferred from Mutant Phenotype, IPI: Inferred from Physical Interaction Assigned on 2002-04-23	manually curated	Bell W, et al.  (1998) Composition and functional analysis of the Saccharomyces cerevisiae trehalose synthase complex. J Biol Chem 273(50):33311-9	SGD
	IEA: Inferred from Electronic Annotation with EBI:IPR001830, EBI:IPR003337 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
TSL1/YML100W	IGI: Inferred from Genetic Interaction, IMP: Inferred from Mutant Phenotype, IPI: Inferred from Physical Interaction Assigned on 2002-04-23	manually curated	Bell W, et al.  (1998) Composition and functional analysis of the Saccharomyces cerevisiae trehalose synthase complex. J Biol Chem 273(50):33311-9	SGD
	IEA: Inferred from Electronic Annotation with EBI:IPR001830, EBI:IPR003337 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
UGP1/YKL035W	IGI: Inferred from Genetic Interaction with SGD:PGM1, SGD:PGM2 Assigned on 2007-10-12	manually curated	Daran JM, et al.  (1997) Physiological and morphological effects of genetic alterations leading to a reduced synthesis of UDP-glucose in Saccharomyces cerevisiae. FEMS Microbiol Lett 153(1):89-96	SGD

SGD Home About Blog Site Map Help Terms of Use
© Stanford University, Stanford, CA 94305.