GO term: plasma membrane 
Ontology: Cellular Component (GO:0005886)
Definition: The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
Synonyms: bacterial inner membrane; cell membrane; cytoplasmic membrane; inner endospore membrane; juxtamembrane; plasmalemma; plasma membrane lipid bilayer
Definition: The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
Synonyms: bacterial inner membrane; cell membrane; cytoplasmic membrane; inner endospore membrane; juxtamembrane; plasmalemma; plasma membrane lipid bilayer
This table lists the methods used to annotate genes either directly to the term
plasma membrane (339 genes)
or to its variants containing one or more
qualifiers (2 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | colocalizes_with: plasma membrane | 1 |
| NOT: plasma membrane | 1 | |
| plasma membrane | 235 | |
| High-throughput (download data) | plasma membrane | 5 |
| Computational (download data) | plasma membrane | 197 |
Links to Additional Annotations:
Annotation details for genes that have been directly annotated to the term
plasma membrane or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| NOT: plasma membrane 1 gene directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| CDC25/YLR310C | IDA: Inferred from Direct Assay Assigned on 2009-04-01 |
manually curated | Tisi R, et al. (2008) The budding yeast RasGEF Cdc25 reveals an unexpected nuclear localization. Biochim Biophys Acta 1783(12):2363-74 |
SGD |
| colocalizes_with: plasma membrane 1 gene directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| SLI1/YGR212W | IDA: Inferred from Direct Assay Assigned on 2005-05-05 |
manually curated | Momoi M, et al. (2004) SLI1 (YGR212W) is a major gene conferring resistance to the sphingolipid biosynthesis inhibitor ISP-1, and encodes an ISP-1 N-acetyltransferase in yeast. Biochem J 381(Pt 1):321-8 |
SGD |
| plasma membrane 339 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| ADI1/YMR009W | IEA: Inferred from Electronic Annotation with EBI:KW-1003 Last Updated 2009-11-20 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| ADY2/YCR010C | IDA: Inferred from Direct Assay Assigned on 2007-04-05 |
manually curated | Ricicova M, et al. (2007) Association of putative ammonium exporters Ato with detergent-resistant compartments of plasma membrane during yeast colony development: pH affects Ato1p localisation in patches. Biochim Biophys Acta 1768(5):1170-1178 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-1003 Last Updated 2009-11-20 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB | |
| AFI1/YOR129C | IMP: Inferred from Mutant Phenotype Assigned on 2008-04-15 |
manually curated | Wysocka M, et al. (2003) YOR129c, a new element interacting with Cnm67p, a component of the spindle pole body of Saccharomyces cerevisiae. Acta Biochim Pol 50(3):883-90 |
SGD |
| IDA: Inferred from Direct Assay, IMP: Inferred from Mutant Phenotype Assigned on 2008-04-15 |
manually curated | Tsai PC, et al. (2008) Afi1p Functions as an Arf3p Polarization-specific Docking Factor for Development of Polarity. J Biol Chem 283(24):16915-27 |
SGD | |
| AGP1/YCL025C | ISS: Inferred from Sequence or structural Similarity Assigned on 2002-08-05 |
manually curated | Regenberg B, et al. (1999) Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae. Curr Genet 36(6):317-28 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-1003 Last Updated 2009-11-20 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB | |
| AGP3/YFL055W | ISS: Inferred from Sequence or structural Similarity Assigned on 2002-10-02 |
manually curated | Regenberg B, et al. (1999) Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae. Curr Genet 36(6):317-28 |
SGD |
| AIF1/YNR074C | ISS: Inferred from Sequence or structural Similarity Assigned on 2001-12-28 |
manually curated | Ververidis P, et al. (2001) A novel putative reductase (Cpd1p) and the multidrug exporter Snq2p are involved in resistance to cercosporin and other singlet oxygen-generating photosensitizers in Saccharomyces cerevisiae. Curr Genet 39(3):127-36 |
SGD |
| ALP1/YNL270C | ISS: Inferred from Sequence or structural Similarity Assigned on 2002-08-05 |
manually curated | Regenberg B, et al. (1999) Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae. Curr Genet 36(6):317-28 |
SGD |
| ALR1/YOL130W | IMP: Inferred from Mutant Phenotype Assigned on 2001-04-12 |
manually curated | MacDiarmid CW and Gardner RC (1998) Overexpression of the Saccharomyces cerevisiae magnesium transport system confers resistance to aluminum ion. J Biol Chem 273(3):1727-32 |
SGD |
| ALR2/YFL050C | IMP: Inferred from Mutant Phenotype Assigned on 2001-04-12 |
manually curated | MacDiarmid CW and Gardner RC (1998) Overexpression of the Saccharomyces cerevisiae magnesium transport system confers resistance to aluminum ion. J Biol Chem 273(3):1727-32 |
SGD |
| APL1/YJR005W | IEA: Inferred from Electronic Annotation with EBI:KW-1003 Last Updated 2009-11-20 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0039 Last Updated 2009-11-20 |
computational | GOA curators and UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. |
UniProtKB | |
| APL2/YKL135C | IEA: Inferred from Electronic Annotation with EBI:KW-1003 Last Updated 2009-11-20 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0039 Last Updated 2009-11-20 |
computational | GOA curators and UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. |
UniProtKB | |
| APL3/YBL037W | IEA: Inferred from Electronic Annotation with EBI:KW-1003 Last Updated 2009-11-20 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0039 Last Updated 2009-11-20 |
computational | GOA curators and UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. |
UniProtKB | |
| APS2/YJR058C | IEA: Inferred from Electronic Annotation with EBI:KW-1003 Last Updated 2009-11-20 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0039 Last Updated 2009-11-20 |
computational | GOA curators and UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. |
UniProtKB | |
| AQR1/YNL065W | IDA: Inferred from Direct Assay Assigned on 2002-12-12 |
manually curated | Tenreiro S, et al. (2002) AQR1 gene (ORF YNL065w) encodes a plasma membrane transporter of the major facilitator superfamily that confers resistance to short-chain monocarboxylic acids and quinidine in Saccharomyces cerevisiae. Biochem Biophys Res Commun 292(3):741-8 |
SGD |
| AQY1/YPR192W | IDA: Inferred from Direct Assay Assigned on 2003-01-08 |
manually curated | Laize V, et al. (1999) Molecular and functional study of AQY1 from Saccharomyces cerevisiae: role of the C-terminal domain. Biochem Biophys Res Commun 257(1):139-44 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-1003 Last Updated 2009-11-20 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB | |
| AQY2/YLL052C | IDA: Inferred from Direct Assay Assigned on 2003-01-08 |
manually curated | Meyrial V, et al. (2001) Existence of a tightly regulated water channel in Saccharomyces cerevisiae. Eur J Biochem 268(2):334-43 |
SGD |
| ARN1/YHL040C | IDA: Inferred from Direct Assay Assigned on 2009-06-30 |
manually curated | Kim Y, et al. (2005) A receptor domain controls the intracellular sorting of the ferrichrome transporter, ARN1. EMBO J 24(5):952-62 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-1003 Last Updated 2009-11-20 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB | |
| ARN2/YHL047C | ISS: Inferred from Sequence or structural Similarity Assigned on 2002-03-14 |
manually curated | Heymann P, et al. (1999) Identification of a fungal triacetylfusarinine C siderophore transport gene (TAF1) in Saccharomyces cerevisiae as a member of the major facilitator superfamily. Biometals 12(4):301-6 |
SGD |
| ASG7/YJL170C | IDA: Inferred from Direct Assay Assigned on 2002-09-16 |
manually curated | Kim J, et al. (2000) Localization and signaling of G(beta) subunit Ste4p are controlled by a-factor receptor and the a-specific protein Asg7p. Mol Cell Biol 20(23):8826-35 |
SGD |
| ATO2/YNR002C | IDA: Inferred from Direct Assay Assigned on 2007-04-05 |
manually curated | Ricicova M, et al. (2007) Association of putative ammonium exporters Ato with detergent-resistant compartments of plasma membrane during yeast colony development: pH affects Ato1p localisation in patches. Biochim Biophys Acta 1768(5):1170-1178 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-1003 Last Updated 2009-11-20 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB | |
| ATO3/YDR384C | IDA: Inferred from Direct Assay Assigned on 2003-12-28 |
manually curated | Guaragnella N and Butow RA (2003) ATO3 encoding a putative outward ammonium transporter is an RTG-independent retrograde responsive gene regulated by GCN4 and the Ssy1-Ptr3-Ssy5 amino acid sensor system. J Biol Chem 278(46):45882-7 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-1003 Last Updated 2009-11-20 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB | |
| ATP5/YDR298C | IEA: Inferred from Electronic Annotation with EBI:IPR000711, EBI:IPR020781 Last Updated 2009-11-20 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
UniProtKB |
| ATR1/YML116W | IDA: Inferred from Direct Assay Assigned on 2009-05-13 |
manually curated | Kaya A, et al. (2009) Identification of a novel system for boron transport: Atr1 is a main boron exporter in yeast. Mol Cell Biol 29(13):3665-74 |
SGD |
| IMP: Inferred from Mutant Phenotype Assigned on 2002-07-12 |
manually curated | Gompel-Klein P and Brendel M (1990) Allelism of SNQ1 and ATR1, genes of the yeast Saccharomyces cerevisiae required for controlling sensitivity to 4-nitroquinoline-N-oxide and aminotriazole. Curr Genet 18(1):93-6 |
SGD | |
| AVO1/YOL078W | IDA: Inferred from Direct Assay Assigned on 2009-01-21 |
manually curated | Berchtold D and Walther TC (2009) TORC2 plasma membrane localization is essential for cell viability and restricted to a distinct domain. Mol Biol Cell 20(5):1565-75 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-1003 Last Updated 2009-11-20 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB | |
| AVO2/YMR068W | IEA: Inferred from Electronic Annotation with EBI:KW-1003 Last Updated 2009-11-20 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| AVT7/YIL088C | IDA: Inferred from Direct Assay Assigned on 2007-04-25 |
manually curated | Russnak R, et al. (2001) A family of yeast proteins mediating bidirectional vacuolar amino acid transport. J Biol Chem 276(26):23849-57 |
SGD |
| AXL2/YIL140W | IEA: Inferred from Electronic Annotation with EBI:KW-1003 Last Updated 2009-11-20 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| AZR1/YGR224W | IDA: Inferred from Direct Assay Assigned on 2004-01-20 |
manually curated | Tenreiro S, et al. (2000) Expression of the AZR1 gene (ORF YGR224w), encoding a plasma membrane transporter of the major facilitator superfamily, is required for adaptation to acetic acid and resistance to azoles in Saccharomyces cerevisiae. Yeast 16(16):1469-81 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-1003 Last Updated 2009-11-20 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB | |
| BAP2/YBR068C | ISS: Inferred from Sequence or structural Similarity Assigned on 2002-08-06 |
manually curated | Regenberg B, et al. (1999) Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae. Curr Genet 36(6):317-28 |
SGD |
| BAP3/YDR046C | ISS: Inferred from Sequence or structural Similarity Assigned on 2002-08-06 |
manually curated | Regenberg B, et al. (1999) Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae. Curr Genet 36(6):317-28 |
SGD |
This diagram shows the local area of the Gene Ontology and the numbers of yeast genes annotated to each term in the diagram. Within the diagram, click on the blue arrow to navigate up the tree and click on a GO term name to go to its GO term page.
View term lineage as a textual display using
View term lineage as a textual display using