GO term: actin filament 
Ontology: Cellular Component (GO:0005884)
Definition: A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
Synonyms: microfilament
View Ontology:
(graph) | 
(text)
Definition: A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
Synonyms: microfilament
View Ontology:
(graph) | (text)
This table lists the methods used to annotate genes either directly to the term
actin filament (5 genes)
or to its variants containing one or more
qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | actin filament | 5 |
| High-throughput | none | none |
| Computational | none | none |
Links to Additional Annotations:
- View
annotations in multiple organisms using
- Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.
Annotation details for genes that have been directly annotated to the term
actin filament or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| actin filament 5 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| ABP140/YOR239W | IDA: Inferred from Direct Assay Assigned on 2001-04-11 |
manually curated | Asakura T, et al. (1998) Isolation and characterization of a novel actin filament-binding protein from Saccharomyces cerevisiae. Oncogene 16(1):121-30 |
SGD |
| ACT1/YFL039C | IDA: Inferred from Direct Assay Assigned on 2013-04-01 |
manually curated | Greer C and Schekman R (1982) Actin from Saccharomyces cerevisiae. Mol Cell Biol 2(10):1270-8 |
SGD |
| BNI1/YNL271C | IDA: Inferred from Direct Assay Assigned on 2003-08-21 |
manually curated | Pruyne D, et al. (2002) Role of formins in actin assembly: nucleation and barbed-end association. Science 297(5581):612-5 |
SGD |
| CAP1/YKL007W | IPI: Inferred from Physical Interaction Assigned on 2004-10-01 |
manually curated | Kim K, et al. (2004) Capping protein binding to actin in yeast: biochemical mechanism and physiological relevance. J Cell Biol 164(4):567-80 |
SGD |
| CAP2/YIL034C | IPI: Inferred from Physical Interaction Assigned on 2004-10-01 |
manually curated | Kim K, et al. (2004) Capping protein binding to actin in yeast: biochemical mechanism and physiological relevance. J Cell Biol 164(4):567-80 |
SGD |
