Ontology: Cellular Component (GO:0005849)

Definition: Any macromolecular complex involved in cleavage or polyadenylation of mRNA molecules.

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term mRNA cleavage factor complex (9 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	mRNA cleavage factor complex	9
High-throughput	none	none
Computational	none	none

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term mRNA cleavage factor complex or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

mRNA cleavage factor complex      9 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
CFT1/YDR301W	IPI: Inferred from Physical Interaction Assigned on 2002-04-10	manually curated	Zhao J, et al.  (1997) Cleavage factor II of Saccharomyces cerevisiae contains homologues to subunits of the mammalian Cleavage/ polyadenylation specificity factor and exhibits sequence-specific, ATP-dependent interaction with precursor RNA. J Biol Chem 272(16):10831-8	SGD
CFT2/YLR115W	IPI: Inferred from Physical Interaction Assigned on 2002-04-10	manually curated	Zhao J, et al.  (1997) Cleavage factor II of Saccharomyces cerevisiae contains homologues to subunits of the mammalian Cleavage/ polyadenylation specificity factor and exhibits sequence-specific, ATP-dependent interaction with precursor RNA. J Biol Chem 272(16):10831-8	SGD
CLP1/YOR250C	IPI: Inferred from Physical Interaction Assigned on 2002-04-09	manually curated	Gross S and Moore C  (2001) Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I. Proc Natl Acad Sci U S A 98(11):6080-5	SGD
HRP1/YOL123W	IPI: Inferred from Physical Interaction Assigned on 2002-04-09	manually curated	Gross S and Moore C  (2001) Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I. Proc Natl Acad Sci U S A 98(11):6080-5	SGD
PCF11/YDR228C	IPI: Inferred from Physical Interaction Assigned on 2002-04-09	manually curated	Gross S and Moore C  (2001) Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I. Proc Natl Acad Sci U S A 98(11):6080-5	SGD
PTA1/YAL043C	IPI: Inferred from Physical Interaction Assigned on 2002-04-10	manually curated	Zhao J, et al.  (1997) Cleavage factor II of Saccharomyces cerevisiae contains homologues to subunits of the mammalian Cleavage/ polyadenylation specificity factor and exhibits sequence-specific, ATP-dependent interaction with precursor RNA. J Biol Chem 272(16):10831-8	SGD
RNA14/YMR061W	IPI: Inferred from Physical Interaction Assigned on 2002-04-09	manually curated	Gross S and Moore C  (2001) Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I. Proc Natl Acad Sci U S A 98(11):6080-5	SGD
RNA15/YGL044C	IPI: Inferred from Physical Interaction Assigned on 2002-04-09	manually curated	Gross S and Moore C  (2001) Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I. Proc Natl Acad Sci U S A 98(11):6080-5	SGD
YSH1/YLR277C	IPI: Inferred from Physical Interaction Assigned on 2002-04-10	manually curated	Zhao J, et al.  (1997) Cleavage factor II of Saccharomyces cerevisiae contains homologues to subunits of the mammalian Cleavage/ polyadenylation specificity factor and exhibits sequence-specific, ATP-dependent interaction with precursor RNA. J Biol Chem 272(16):10831-8	SGD

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