Ontology: Cellular Component (GO:0005840)
Definition: An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.
Synonyms: ribosomal RNA; free ribosome; membrane bound ribosome
View Ontology:
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(text)
Definition: An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.
Synonyms: ribosomal RNA; free ribosome; membrane bound ribosome
View Ontology:
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This table lists the methods used to annotate genes either directly to the term
ribosome (234 genes)
or to its variants containing one or more
qualifiers (76 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | colocalizes_with: ribosome | 13 |
| ribosome | 18 | |
| High-throughput (download data) | colocalizes_with: ribosome | 64 |
| Computational (download data) | ribosome | 216 |
Links to Additional Annotations:
- View
annotations in multiple organisms using

- Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.
Annotation details for genes that have been directly annotated to the term
ribosome or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| ribosome 234 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| CDC33/YOL139C | TAS: Traceable Author Statement Assigned on 2001-01-24 |
manually curated | McCarthy JE (1998) Posttranscriptional control of gene expression in yeast. Microbiol Mol Biol Rev 62(4):1492-553 | SGD |
| EFT1/YOR133W | TAS: Traceable Author Statement Assigned on 2001-01-24 |
manually curated | McCarthy JE (1998) Posttranscriptional control of gene expression in yeast. Microbiol Mol Biol Rev 62(4):1492-553 | SGD |
| EFT2/YDR385W | TAS: Traceable Author Statement Assigned on 2001-01-24 |
manually curated | McCarthy JE (1998) Posttranscriptional control of gene expression in yeast. Microbiol Mol Biol Rev 62(4):1492-553 | SGD |
| GCD11/YER025W | TAS: Traceable Author Statement Assigned on 2001-01-24 |
manually curated | McCarthy JE (1998) Posttranscriptional control of gene expression in yeast. Microbiol Mol Biol Rev 62(4):1492-553 | SGD |
| IMG1/YCR046C | IEA: Inferred from Electronic Annotation with EBI:IPR001857 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0689 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| IMG2/YCR071C | IEA: Inferred from Electronic Annotation with EBI:IPR007740 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0689 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| MNP1/YGL068W | IEA: Inferred from Electronic Annotation with EBI:IPR008932, EBI:IPR013823 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0689 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| MRP1/YDR347W | IEA: Inferred from Electronic Annotation with EBI:KW-0689 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| MRP10/YDL045W-A | IEA: Inferred from Electronic Annotation with EBI:KW-0689 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| MRP13/YGR084C | IEA: Inferred from Electronic Annotation with EBI:KW-0689 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| MRP17/YKL003C | IEA: Inferred from Electronic Annotation with EBI:IPR000529 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0689 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| MRP2/YPR166C | IEA: Inferred from Electronic Annotation with EBI:IPR018271, EBI:IPR001209 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0689 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| MRP20/YDR405W | IEA: Inferred from Electronic Annotation with EBI:IPR013025, EBI:IPR012678 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0689 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| MRP21/YBL090W | IEA: Inferred from Electronic Annotation with EBI:IPR001911 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0689 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| MRP4/YHL004W | IEA: Inferred from Electronic Annotation with EBI:IPR018130, EBI:IPR001865 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0689 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| MRP49/YKL167C | IEA: Inferred from Electronic Annotation with EBI:KW-0689 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| MRP51/YPL118W | IEA: Inferred from Electronic Annotation with EBI:KW-0689 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| MRP7/YNL005C | IEA: Inferred from Electronic Annotation with EBI:IPR018261, EBI:IPR001684 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0689 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| MRPL1/YDR116C | IEA: Inferred from Electronic Annotation with EBI:KW-0689 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| MRPL10/YNL284C | IEA: Inferred from Electronic Annotation with EBI:KW-0689 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| MRPL11/YDL202W | IEA: Inferred from Electronic Annotation with EBI:KW-0689 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| MRPL13/YKR006C | IEA: Inferred from Electronic Annotation with EBI:KW-0689 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| MRPL15/YLR312W-A | IEA: Inferred from Electronic Annotation with EBI:KW-0689 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| MRPL16/YBL038W | IEA: Inferred from Electronic Annotation with EBI:IPR020798, EBI:IPR016180 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0689 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| MRPL17/YNL252C | IEA: Inferred from Electronic Annotation with EBI:KW-0689 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| MRPL19/YNL185C | IEA: Inferred from Electronic Annotation with EBI:IPR006519, EBI:IPR020783, EBI:IPR000911 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0689 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| MRPL20/YKR085C | IEA: Inferred from Electronic Annotation with EBI:KW-0689 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| MRPL22/YNL177C | IEA: Inferred from Electronic Annotation with EBI:IPR001063 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0689 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| MRPL23/YOR150W | IEA: Inferred from Electronic Annotation with EBI:IPR005822, EBI:IPR005823, EBI:IPR023563, EBI:IPR023564 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0689 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| MRPL24/YMR193W | IEA: Inferred from Electronic Annotation with EBI:IPR001383 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro |
| IEA: Inferred from Electronic Annotation with EBI:KW-0689 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| colocalizes_with: ribosome 76 genes directly annotated to this term |
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|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| AIM14/YGL160W | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| AIM21/YIR003W | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| ALB1/YJL122W | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| ALE1/YOR175C | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| APE4/YHR113W | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| ARB1/YER036C | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| BCH1/YMR237W | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| CDC28/YBR160W | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| DUG1/YFR044C | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| ESL2/YKR096W | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| FRD1/YEL047C | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| GDE1/YPL110C | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| GIP3/YPL137C | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| HEL2/YDR266C | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| HER1/YOR227W | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| IMA1/YGR287C | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| LAA1/YJL207C | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| LSM12/YHR121W | IDA: Inferred from Direct Assay Assigned on 2006-12-14 |
manually curated | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| MDY2/YOL111C | IDA: Inferred from Direct Assay Assigned on 2006-12-14 |
manually curated | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| MPP6/YNR024W | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| MRPS12/YNR036C | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| MTC1/YJL123C | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| NBA1/YOL070C | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| NOP1/YDL014W | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| NSI1/YDR026C | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| NVJ2/YPR091C | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| OTU2/YHL013C | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| PML39/YML107C | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| POM33/YLL023C | IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD |
| RKR1/YMR247C | IDA: Inferred from Direct Assay Assigned on 2010-11-19 |
manually curated | Bengtson MH and Joazeiro CA (2010) Role of a ribosome-associated E3 ubiquitin ligase in protein quality control. Nature 467(7314):470-3 | SGD |
| IDA: Inferred from Direct Assay Assigned on 2007-01-22 |
high-throughput | Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 | SGD | |




