GO term: cytosol 
Ontology: Cellular Component (GO:0005829)
Definition: The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
View Ontology:
(graph) | 
(text)
Definition: The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
View Ontology:
(graph) | (text)
This table lists the methods used to annotate genes either directly to the term
cytosol (592 genes)
or to its variants containing one or more
qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | cytosol | 574 |
| High-throughput (download data) | cytosol | 2 |
| Computational (download data) | cytosol | 18 |
Links to Additional Annotations:
- View
annotations in multiple organisms using
- Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.
Annotation details for genes that have been directly annotated to the term
cytosol or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| cytosol 592 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| AAH1/YNL141W | IBA: Inferred from Biological Aspect of Ancestor with PANTHER:PTHR11409_AN174 Assigned on 2011-06-14 |
computational | Gaudet P, et al. (2011) Annotation inferences using phylogenetic trees. |
RefGenome |
| AAT2/YLR027C | IDA: Inferred from Direct Assay Assigned on 2008-01-21 |
manually curated | Verleur N, et al. (1997) Cytosolic aspartate aminotransferase encoded by the AAT2 gene is targeted to the peroxisomes in oleate-grown Saccharomyces cerevisiae. Eur J Biochem 247(3):972-80 |
SGD |
| ABD1/YBR236C | IDA: Inferred from Direct Assay Assigned on 2013-06-06 |
manually curated | Ghosh Dastidar R, et al. (2012) The nuclear localization of SWI/SNF proteins is subjected to oxygen regulation. Cell Biosci 2(1):30 |
SGD |
| ACE2/YLR131C | IDA: Inferred from Direct Assay Assigned on 2005-10-12 |
manually curated | Dohrmann PR, et al. (1992) Parallel pathways of gene regulation: homologous regulators SWI5 and ACE2 differentially control transcription of HO and chitinase. Genes Dev 6(1):93-104 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2005-10-12 |
manually curated | Archambault V, et al. (2004) Targeted proteomic study of the cyclin-Cdk module. Mol Cell 14(6):699-711 |
SGD | |
| ACH1/YBL015W | IDA: Inferred from Direct Assay Assigned on 2002-11-25 |
manually curated | de Nobel H, et al. (2001) Parallel and comparative analysis of the proteome and transcriptome of sorbic acid-stressed Saccharomyces cerevisiae. Yeast 18(15):1413-28 |
SGD |
| ACO1/YLR304C | IDA: Inferred from Direct Assay Assigned on 2011-04-18 |
manually curated | Regev-Rudzki N, et al. (2005) Yeast aconitase in two locations and two metabolic pathways: seeing small amounts is believing. Mol Biol Cell 16(9):4163-71 |
SGD |
| ACS1/YAL054C | IDA: Inferred from Direct Assay Assigned on 2002-09-20 |
manually curated | de Jong-Gubbels P, et al. (1998) Overproduction of acetyl-coenzyme A synthetase isoenzymes in respiring Saccharomyces cerevisiae cells does not reduce acetate production after exposure to glucose excess. FEMS Microbiol Lett 165(1):15-20 |
SGD |
| ACS2/YLR153C | IDA: Inferred from Direct Assay Assigned on 2006-11-07 |
manually curated | Takahashi H, et al. (2006) Nucleocytosolic acetyl-coenzyme a synthetase is required for histone acetylation and global transcription. Mol Cell 23(2):207-17 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2002-09-20 |
manually curated | de Jong-Gubbels P, et al. (1998) Overproduction of acetyl-coenzyme A synthetase isoenzymes in respiring Saccharomyces cerevisiae cells does not reduce acetate production after exposure to glucose excess. FEMS Microbiol Lett 165(1):15-20 |
SGD | |
| ADD66/YKL206C | IDA: Inferred from Direct Assay Assigned on 2008-10-24 |
manually curated | Scott CM, et al. (2007) ADD66, a Gene Involved in the Endoplasmic Reticulum-associated Degradation of {alpha}-1-Antitrypsin-Z in Yeast, Facilitates Proteasome Activity and Assembly. Mol Biol Cell 18(10):3776-87 |
SGD |
| ADE16/YLR028C | IDA: Inferred from Direct Assay Assigned on 2001-06-26 |
manually curated | Tibbetts AS and Appling DR (2000) Characterization of two 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase isozymes from Saccharomyces cerevisiae. J Biol Chem 275(27):20920-7 |
SGD |
| ADE17/YMR120C | IDA: Inferred from Direct Assay Assigned on 2001-06-26 |
manually curated | Tibbetts AS and Appling DR (2000) Characterization of two 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase isozymes from Saccharomyces cerevisiae. J Biol Chem 275(27):20920-7 |
SGD |
| ADK1/YDR226W | IEA: Inferred from Electronic Annotation with EBI:SL-0091 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. |
UniProtKB |
| ALD6/YPL061W | IMP: Inferred from Mutant Phenotype Assigned on 2009-08-21 |
manually curated | Meaden PG, et al. (1997) The ALD6 gene of Saccharomyces cerevisiae encodes a cytosolic, Mg(2+)-activated acetaldehyde dehydrogenase. Yeast 13(14):1319-27 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2007-01-04 |
manually curated | Rinnerthaler M, et al. (2006) MMI1 (YKL056c, TMA19), the yeast orthologue of the translationally controlled tumor protein (TCTP) has apoptotic functions and interacts with both microtubules and mitochondria. Biochim Biophys Acta 1757(5-6):631-8 |
SGD | |
| ALG13/YGL047W | IDA: Inferred from Direct Assay Assigned on 2005-11-09 |
manually curated | Bickel T, et al. (2005) Biosynthesis of lipid-linked oligosaccharides in Saccharomyces cerevisiae: Alg13p and Alg14p form a complex required for the formation of GlcNAc(2)-PP-dolichol. J Biol Chem 280(41):34500-6 |
SGD |
| AOS1/YPR180W | IDA: Inferred from Direct Assay Assigned on 2013-06-06 |
manually curated | Ghosh Dastidar R, et al. (2012) The nuclear localization of SWI/SNF proteins is subjected to oxygen regulation. Cell Biosci 2(1):30 |
SGD |
| ARA1/YBR149W | IDA: Inferred from Direct Assay Assigned on 2003-09-12 |
manually curated | Kim ST, et al. (1998) D-arabinose dehydrogenase and its gene from Saccharomyces cerevisiae. Biochim Biophys Acta 1429(1):29-39 |
SGD |
| ARC35/YNR035C | IPI: Inferred from Physical Interaction Assigned on 2004-10-31 |
manually curated | Schaerer-Brodbeck C and Riezman H (2003) Genetic and biochemical interactions between the Arp2/3 complex, Cmd1p, casein kinase II, and Tub4p in yeast. FEMS Yeast Res 4(1):37-49 |
SGD |
| ARG1/YOL058W | IDA: Inferred from Direct Assay Assigned on 2001-01-18 |
manually curated | Jauniaux JC, et al. (1978) Arginine metabolism in Saccharomyces cerevisiae: subcellular localization of the enzymes. J Bacteriol 133(3):1096-1107 |
SGD |
| ARG3/YJL088W | IDA: Inferred from Direct Assay Assigned on 2001-01-18 |
manually curated | Jauniaux JC, et al. (1978) Arginine metabolism in Saccharomyces cerevisiae: subcellular localization of the enzymes. J Bacteriol 133(3):1096-1107 |
SGD |
| ARG4/YHR018C | IDA: Inferred from Direct Assay Assigned on 2001-01-18 |
manually curated | Jauniaux JC, et al. (1978) Arginine metabolism in Saccharomyces cerevisiae: subcellular localization of the enzymes. J Bacteriol 133(3):1096-1107 |
SGD |
| ARL1/YBR164C | IDA: Inferred from Direct Assay Assigned on 2010-10-19 |
manually curated | Liu YW, et al. (2005) Role for Gcs1p in regulation of Arl1p at trans-Golgi compartments. Mol Biol Cell 16(9):4024-33 |
SGD |
| ASF1/YJL115W | IDA: Inferred from Direct Assay Assigned on 2013-06-06 |
manually curated | Ghosh Dastidar R, et al. (2012) The nuclear localization of SWI/SNF proteins is subjected to oxygen regulation. Cell Biosci 2(1):30 |
SGD |
| ATG1/YGL180W | IDA: Inferred from Direct Assay Assigned on 2001-01-18 |
manually curated | Straub M, et al. (1997) AUT3, a serine/threonine kinase gene, is essential for autophagocytosis in Saccharomyces cerevisiae. J Bacteriol 179(12):3875-83 |
SGD |
| ATG18/YFR021W | IDA: Inferred from Direct Assay Assigned on 2001-11-19 |
manually curated | Barth H, et al. (2001) Autophagy and the cytoplasm to vacuole targeting pathway both require Aut10p. FEBS Lett 508(1):23-8 |
SGD |
| ATG21/YPL100W | IDA: Inferred from Direct Assay Assigned on 2002-08-14 |
manually curated | Barth H, et al. (2002) Mai1p is essential for maturation of proaminopeptidase I but not for autophagy. FEBS Lett 512(1-3):173-9 |
SGD |
| ATG3/YNR007C | IDA: Inferred from Direct Assay Assigned on 2005-03-23 |
manually curated | Kim J, et al. (2001) Membrane recruitment of Aut7p in the autophagy and cytoplasm to vacuole targeting pathways requires Aut1p, Aut2p, and the autophagy conjugation complex. J Cell Biol 152(1):51-64 |
UniProtKB |
| ATG4/YNL223W | IDA: Inferred from Direct Assay Assigned on 2007-01-19 |
manually curated | Kim J, et al. (2001) Membrane recruitment of Aut7p in the autophagy and cytoplasm to vacuole targeting pathways requires Aut1p, Aut2p, and the autophagy conjugation complex. J Cell Biol 152(1):51-64 |
UniProtKB |
| ATG5/YPL149W | IDA: Inferred from Direct Assay Assigned on 2003-04-10 |
manually curated | Kuma A, et al. (2002) Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast. J Biol Chem 277(21):18619-25 |
SGD |
| ATG7/YHR171W | IDA: Inferred from Direct Assay Assigned on 2005-10-17 |
manually curated | Tanida I, et al. (1999) Apg7p/Cvt2p: A novel protein-activating enzyme essential for autophagy. Mol Biol Cell 10(5):1367-79 |
SGD |
| ATG8/YBL078C | IDA: Inferred from Direct Assay Assigned on 2005-03-23 |
manually curated | Kim J, et al. (2001) Membrane recruitment of Aut7p in the autophagy and cytoplasm to vacuole targeting pathways requires Aut1p, Aut2p, and the autophagy conjugation complex. J Cell Biol 152(1):51-64 |
UniProtKB |
