Ontology: Cellular Component (GO:0005811)

Definition: Any particle of coalesced lipids in the cytoplasm of a cell. May include associated proteins.

Synonyms: lipid droplet; adiposome; lipid body

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term lipid particle (43 genes) or to its variants containing one or more qualifiers (2 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	colocalizes_with: lipid particle	2
	lipid particle	34
High-throughput (download data)	lipid particle	10
Computational (download data)	lipid particle	25

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term lipid particle or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

colocalizes_with: lipid particle      2 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
TGL3/YMR313C	IDA: Inferred from Direct Assay Assigned on 2006-05-22	manually curated	Kurat CF, et al.  (2006) Obese yeast: triglyceride lipolysis is functionally conserved from mammals to yeast. J Biol Chem 281(1):491-500	SGD
TGL4/YKR089C	IDA: Inferred from Direct Assay Assigned on 2006-05-22	manually curated	Kurat CF, et al.  (2006) Obese yeast: triglyceride lipolysis is functionally conserved from mammals to yeast. J Biol Chem 281(1):491-500	SGD

lipid particle      43 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
ATF1/YOR377W	IDA: Inferred from Direct Assay Assigned on 2004-04-03	manually curated	Verstrepen KJ, et al.  (2004) The Saccharomyces cerevisiae alcohol acetyl transferase Atf1p is localized in lipid particles. Yeast 21(4):367-77	SGD
AYR1/YIL124W	IDA: Inferred from Direct Assay Assigned on 2001-01-18	manually curated	Athenstaedt K and Daum G  (2000) 1-Acyldihydroxyacetone-phosphate reductase (Ayr1p) of the yeast Saccharomyces cerevisiae encoded by the open reading frame YIL124w is a major component of lipid particles. J Biol Chem 275(1):235-40	SGD
	IEA: Inferred from Electronic Annotation with EBI:KW-0551 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
	IEA: Inferred from Electronic Annotation with EBI:SL-0154 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries.	UniProtKB
BSC2/YDR275W	IDA: Inferred from Direct Assay Assigned on 2003-10-28	high-throughput	Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91	SGD
	IEA: Inferred from Electronic Annotation with EBI:KW-0551 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
	IEA: Inferred from Electronic Annotation with EBI:SL-0154 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries.	UniProtKB
CSR1/YLR380W	IDA: Inferred from Direct Assay Assigned on 2008-04-08	manually curated	Desfougeres T, et al.  (2008) SFH2 regulates fatty acid synthase activity in the yeast Saccharomyces cerevisiae and is critical to prevent saturated fatty acid accumulation in response to haem and oleic acid depletion. Biochem J 409(1):299-309	SGD
CST26/YBR042C	IDA: Inferred from Direct Assay Assigned on 2003-10-28	high-throughput	Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91	SGD
	IEA: Inferred from Electronic Annotation with EBI:KW-0551 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
	IEA: Inferred from Electronic Annotation with EBI:SL-0154 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries.	UniProtKB
DGA1/YOR245C	IDA: Inferred from Direct Assay Assigned on 2002-08-16	manually curated	Sorger D and Daum G  (2002) Synthesis of triacylglycerols by the acyl-coenzyme A:diacyl-glycerol acyltransferase Dga1p in lipid particles of the yeast Saccharomyces cerevisiae. J Bacteriol 184(2):519-24	SGD
	IEA: Inferred from Electronic Annotation with EBI:KW-0551 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
	IEA: Inferred from Electronic Annotation with EBI:SL-0154 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries.	UniProtKB
EHT1/YBR177C	IDA: Inferred from Direct Assay Assigned on 2001-01-18	manually curated	Athenstaedt K, et al.  (1999) Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae. J Bacteriol 181(20):6441-8	SGD
ENV9/YOR246C	IDA: Inferred from Direct Assay Assigned on 2003-10-28	high-throughput	Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91	SGD
	IEA: Inferred from Electronic Annotation with EBI:KW-0551 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
	IEA: Inferred from Electronic Annotation with EBI:SL-0154 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries.	UniProtKB
ERG1/YGR175C	IDA: Inferred from Direct Assay Assigned on 2001-01-18	manually curated	Leber R, et al.  (1998) Dual localization of squalene epoxidase, Erg1p, in yeast reflects a relationship between the endoplasmic reticulum and lipid particles. Mol Biol Cell 9(2):375-86	SGD
ERG27/YLR100W	IEA: Inferred from Electronic Annotation with EBI:KW-0551 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
	IEA: Inferred from Electronic Annotation with EBI:SL-0154 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries.	UniProtKB
ERG6/YML008C	IDA: Inferred from Direct Assay Assigned on 2001-01-18	manually curated	Athenstaedt K, et al.  (1999) Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae. J Bacteriol 181(20):6441-8	SGD
ERG7/YHR072W	IDA: Inferred from Direct Assay Assigned on 2013-03-11	manually curated	Milla P, et al.  (2002) Yeast oxidosqualene cyclase (Erg7p) is a major component of lipid particles. J Biol Chem 277(4):2406-12	SGD
	IDA: Inferred from Direct Assay Assigned on 2002-09-17	manually curated	Athenstaedt K, et al.  (1999) Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae. J Bacteriol 181(20):6441-8	SGD
	IEA: Inferred from Electronic Annotation with EBI:KW-0551 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
	IEA: Inferred from Electronic Annotation with EBI:SL-0154 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries.	UniProtKB
FAA1/YOR317W	IDA: Inferred from Direct Assay Assigned on 2002-09-17	manually curated	Athenstaedt K, et al.  (1999) Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae. J Bacteriol 181(20):6441-8	SGD
FAA4/YMR246W	IDA: Inferred from Direct Assay Assigned on 2002-09-17	manually curated	Athenstaedt K, et al.  (1999) Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae. J Bacteriol 181(20):6441-8	SGD
FAS1/YKL182W	IDA: Inferred from Direct Assay Assigned on 2008-04-08	manually curated	Desfougeres T, et al.  (2008) SFH2 regulates fatty acid synthase activity in the yeast Saccharomyces cerevisiae and is critical to prevent saturated fatty acid accumulation in response to haem and oleic acid depletion. Biochem J 409(1):299-309	SGD
FAT1/YBR041W	IDA: Inferred from Direct Assay Assigned on 2001-01-18	manually curated	Athenstaedt K, et al.  (1999) Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae. J Bacteriol 181(20):6441-8	SGD
GPT2/YKR067W	IDA: Inferred from Direct Assay Assigned on 2012-08-10	manually curated	Athenstaedt K and Daum G  (1997) Biosynthesis of phosphatidic acid in lipid particles and endoplasmic reticulum of Saccharomyces cerevisiae. J Bacteriol 179(24):7611-6	SGD
	IDA: Inferred from Direct Assay Assigned on 2012-08-10	manually curated	Marr N, et al.  (2012) Controlling lipid fluxes at glycerol-3-phosphate acyltransferase step in yeast: unique contribution of Gat1p to oleic acid-induced lipid particle formation. J Biol Chem 287(13):10251-64	SGD
HFD1/YMR110C	IDA: Inferred from Direct Assay Assigned on 2003-10-28	high-throughput	Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91	SGD
LDB16/YCL005W	IDA: Inferred from Direct Assay Assigned on 2003-10-28	high-throughput	Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91	SGD
	IEA: Inferred from Electronic Annotation with EBI:KW-0551 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
	IEA: Inferred from Electronic Annotation with EBI:SL-0154 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries.	UniProtKB
LDH1/YBR204C	IDA: Inferred from Direct Assay Assigned on 2011-05-20	manually curated	Thoms S, et al.  (2011) The putative Saccharomyces cerevisiae hydrolase Ldh1p is localized to lipid droplets. Eukaryot Cell 10(6):770-5	SGD
	IEA: Inferred from Electronic Annotation with EBI:KW-0551 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
	IEA: Inferred from Electronic Annotation with EBI:SL-0154 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries.	UniProtKB
LOA1/YPR139C	IDA: Inferred from Direct Assay Assigned on 2011-11-22	manually curated	Grillitsch K, et al.  (2011) Lipid particles/droplets of the yeast Saccharomyces cerevisiae revisited: lipidome meets proteome. Biochim Biophys Acta 1811(12):1165-76	SGD
	IDA: Inferred from Direct Assay Assigned on 2011-11-22	manually curated	Ayciriex S, et al.  (2011) YPR139c/LOA1 encodes a novel lysophosphatidic acid acyltransferase associated with lipid droplets and involved in TAG homeostasis. Mol Biol Cell 23(2):233-246	SGD
	IEA: Inferred from Electronic Annotation with EBI:KW-0551 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
	IEA: Inferred from Electronic Annotation with EBI:SL-0154 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries.	UniProtKB
LRO1/YNR008W	IDA: Inferred from Direct Assay Assigned on 2012-04-09	manually curated	Wang CW and Lee SC  (2012) The ubiquitin-like (UBX)-domain-containing protein Ubx2/Ubxd8 regulates lipid droplet homeostasis. J Cell Sci 125(Pt 12):2930-9	SGD
NUS1/YDL193W	IDA: Inferred from Direct Assay Assigned on 2001-06-26	manually curated	Athenstaedt K, et al.  (1999) Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae. J Bacteriol 181(20):6441-8	SGD
	IDA: Inferred from Direct Assay Assigned on 2004-01-05	high-throughput	Hazbun TR, et al.  (2003) Assigning function to yeast proteins by integration of technologies. Mol Cell 12(6):1353-65	SGD
	IEA: Inferred from Electronic Annotation with EBI:KW-0551 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
	IEA: Inferred from Electronic Annotation with EBI:SL-0154 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries.	UniProtKB
PDR16/YNL231C	IDA: Inferred from Direct Assay Assigned on 2003-10-01	manually curated	Schnabl M, et al.  (2003) Subcellular localization of yeast Sec14 homologues and their involvement in regulation of phospholipid turnover. Eur J Biochem 270(15):3133-45	SGD
	IEA: Inferred from Electronic Annotation with EBI:KW-0551 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
	IEA: Inferred from Electronic Annotation with EBI:SL-0154 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries.	UniProtKB
PET10/YKR046C	IDA: Inferred from Direct Assay Assigned on 2002-09-17	manually curated	Athenstaedt K, et al.  (1999) Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae. J Bacteriol 181(20):6441-8	SGD
	IEA: Inferred from Electronic Annotation with EBI:KW-0551 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
	IEA: Inferred from Electronic Annotation with EBI:SL-0154 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries.	UniProtKB
PGC1/YPL206C	IDA: Inferred from Direct Assay Assigned on 2009-08-19	manually curated	Beilharz T, et al.  (2003) Bipartite signals mediate subcellular targeting of tail-anchored membrane proteins in Saccharomyces cerevisiae. J Biol Chem 278(10):8219-23	SGD
PIL1/YGR086C	IEA: Inferred from Electronic Annotation with EBI:KW-0551 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
	IEA: Inferred from Electronic Annotation with EBI:SL-0154 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries.	UniProtKB
RRT8/YOL048C	IDA: Inferred from Direct Assay Assigned on 2003-10-28	high-throughput	Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91	SGD
	IEA: Inferred from Electronic Annotation with EBI:KW-0551 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
	IEA: Inferred from Electronic Annotation with EBI:SL-0154 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries.	UniProtKB
SLC1/YDL052C	IDA: Inferred from Direct Assay Assigned on 2002-09-17	manually curated	Athenstaedt K, et al.  (1999) Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae. J Bacteriol 181(20):6441-8	SGD
SNA2/YDR525W-A	IEA: Inferred from Electronic Annotation with EBI:KW-0551 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries.	UniProtKB
	IEA: Inferred from Electronic Annotation with EBI:SL-0154 Last Updated 2013-03-02	computational	UniProt-GOA  (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries.	UniProtKB

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