GO term: Golgi apparatus 
Ontology: Cellular Component (GO:0005794)
Definition: A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
Synonyms: Golgi; Golgi complex; Golgi ribbon
Definition: A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
Synonyms: Golgi; Golgi complex; Golgi ribbon
This table lists the methods used to annotate genes either directly to the term
Golgi apparatus (215 genes)
or to its variants containing one or more
qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | Golgi apparatus | 58 |
| High-throughput (download data) | Golgi apparatus | 9 |
| Computational (download data) | Golgi apparatus | 193 |
Links to Additional Annotations:
Annotation details for genes that have been directly annotated to the term
Golgi apparatus or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| Golgi apparatus 215 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| AGE2/YIL044C | IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0132 Last Updated 2009-10-01 |
computational | GOA curators and UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. |
UniProtKB | |
| AKR1/YDR264C | IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| RCA: Reviewed Computational Analysis Assigned on 2009-09-03 |
computational | Tian W, et al. (2008) Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function. Genome Biol 9 Suppl 1:S7 |
YeastFunc | |
| ANP1/YEL036C | IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| APL4/YPR029C | IEA: Inferred from Electronic Annotation with EBI:IPR017107 Last Updated 2009-10-01 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB | |
| APL5/YPL195W | IEA: Inferred from Electronic Annotation with EBI:IPR017105 Last Updated 2009-10-01 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. |
UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB | |
| IEA: Inferred from Electronic Annotation with EBI:SL-0132 Last Updated 2009-10-01 |
computational | GOA curators and UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. |
UniProtKB | |
| RCA: Reviewed Computational Analysis Assigned on 2009-09-03 |
computational | Tian W, et al. (2008) Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function. Genome Biol 9 Suppl 1:S7 |
YeastFunc | |
| APL6/YGR261C | IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0132 Last Updated 2009-10-01 |
computational | GOA curators and UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. |
UniProtKB | |
| RCA: Reviewed Computational Analysis Assigned on 2009-09-03 |
computational | Tian W, et al. (2008) Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function. Genome Biol 9 Suppl 1:S7 |
YeastFunc | |
| APM3/YBR288C | IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0132 Last Updated 2009-10-01 |
computational | GOA curators and UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. |
UniProtKB | |
| APS1/YLR170C | IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0132 Last Updated 2009-10-01 |
computational | GOA curators and UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. |
UniProtKB | |
| APS3/YJL024C | IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0132 Last Updated 2009-10-01 |
computational | GOA curators and UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. |
UniProtKB | |
| ARF1/YDL192W | IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0132 Last Updated 2009-10-01 |
computational | GOA curators and UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. |
UniProtKB | |
| ARF2/YDL137W | IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0132 Last Updated 2009-10-01 |
computational | GOA curators and UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. |
UniProtKB | |
| ARF3/YOR094W | IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0132 Last Updated 2009-10-01 |
computational | GOA curators and UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. |
UniProtKB | |
| ARL1/YBR164C | IDA: Inferred from Direct Assay Assigned on 2005-05-23 |
manually curated | Behnia R, et al. (2004) Targeting of the Arf-like GTPase Arl3p to the Golgi requires N-terminal acetylation and the membrane protein Sys1p. Nat Cell Biol 6(5):405-13 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2005-06-15 |
manually curated | Burd CG, et al. (2004) Arf-like GTPases: not so Arf-like after all. Trends Cell Biol 14(12):687-94 |
SGD | |
| IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB | |
| IEA: Inferred from Electronic Annotation with EBI:SL-0132 Last Updated 2009-10-01 |
computational | GOA curators and UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. |
UniProtKB | |
| ARL3/YPL051W | IDA: Inferred from Direct Assay Assigned on 2005-05-23 |
manually curated | Behnia R, et al. (2004) Targeting of the Arf-like GTPase Arl3p to the Golgi requires N-terminal acetylation and the membrane protein Sys1p. Nat Cell Biol 6(5):405-13 |
SGD |
| IDA: Inferred from Direct Assay Assigned on 2005-05-23 |
manually curated | Setty SR, et al. (2004) Golgi targeting of ARF-like GTPase Arl3p requires its Nalpha-acetylation and the integral membrane protein Sys1p. Nat Cell Biol 6(5):414-9 |
SGD | |
| IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB | |
| IEA: Inferred from Electronic Annotation with EBI:SL-0132 Last Updated 2009-10-01 |
computational | GOA curators and UniProt curators (2007) Gene Ontology annotation based on Swiss-Prot Subcellular Location vocabulary mapping. |
UniProtKB | |
| ARV1/YLR242C | IDA: Inferred from Direct Assay Assigned on 2003-01-23 |
manually curated | Swain E, et al. (2002) Yeast cells lacking the ARV1 gene harbor defects in sphingolipid metabolism. Complementation by human ARV1. J Biol Chem 277(39):36152-60 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB | |
| ATG15/YCR068W | IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| ATG27/YJL178C | IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| ATX2/YOR079C | IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| AUR1/YKL004W | IDA: Inferred from Direct Assay Assigned on 2002-07-11 |
manually curated | Levine TP, et al. (2000) Inositol phosphorylceramide synthase is located in the Golgi apparatus of Saccharomyces cerevisiae. Mol Biol Cell 11(7):2267-81 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB | |
| BCH1/YMR237W | IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| BCH2/YKR027W | IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| BET1/YIL004C | IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| BET3/YKR068C | IDA: Inferred from Direct Assay Assigned on 2005-03-14 |
manually curated | Kim YG, et al. (2005) Crystal structure of bet3 reveals a novel mechanism for Golgi localization of tethering factor TRAPP. Nat Struct Mol Biol 12(1):38-45 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB | |
| BET5/YML077W | IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| BOS1/YLR078C | IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| BSC6/YOL137W | IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| BUD7/YOR299W | IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| CCC1/YLR220W | IDA: Inferred from Direct Assay Assigned on 2001-06-08 |
manually curated | Lapinskas PJ, et al. (1996) The role of the Saccharomyces cerevisiae CCC1 gene in the homeostasis of manganese ions. Mol Microbiol 21(3):519-28 |
SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB | |
| CCC2/YDR270W | IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
| CHS5/YLR330W | IEA: Inferred from Electronic Annotation with EBI:KW-0333 Last Updated 2009-10-01 |
computational | GOA curators (2000) Gene Ontology annotation based on Swiss-Prot keyword mapping. |
UniProtKB |
This diagram shows the local area of the Gene Ontology and the numbers of yeast genes annotated to each term in the diagram. Within the diagram, click on the blue arrow to navigate up the tree and click on a GO term name to go to its GO term page.
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