Ontology: Cellular Component (GO:0005743)
Definition: The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
Synonyms: inner mitochondrial membrane
View Ontology:
(graph) |
(text)
Definition: The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
Synonyms: inner mitochondrial membrane
View Ontology:
(graph) |
This table lists the methods used to annotate genes either directly to the term
mitochondrial inner membrane (217 genes)
or to its variants containing one or more
qualifiers (1 gene). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.
Links to Additional Annotations:
| Annotation Method | GO Term | # Yeast Genes Annotated |
|---|---|---|
| Manually curated (download data) | colocalizes_with: mitochondrial inner membrane | 1 |
| mitochondrial inner membrane | 96 | |
| High-throughput | none | none |
| Computational (download data) | mitochondrial inner membrane | 200 |
Links to Additional Annotations:
- View
annotations in multiple organisms using

- Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.
Annotation details for genes that have been directly annotated to the term
mitochondrial inner membrane or its variants containing one or more
qualifiers (NOT, contributes to, or colocalizes with).
| colocalizes_with: mitochondrial inner membrane 1 gene directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| FZO1/YBR179C | IDA: Inferred from Direct Assay Assigned on 2005-05-10 |
manually curated | Fritz S, et al. (2001) Connection of the mitochondrial outer and inner membranes by Fzo1 is critical for organellar fusion. J Cell Biol 152(4):683-92 | SGD |
| mitochondrial inner membrane 217 genes directly annotated to this term |
||||
|---|---|---|---|---|
| Locus | Evidence | Annotation Method | Reference | Assigned By |
| AAC1/YMR056C | IDA: Inferred from Direct Assay Assigned on 2013-02-17 |
manually curated | Dyall SD, et al. (2003) The dynamic dimerization of the yeast ADP/ATP carrier in the inner mitochondrial membrane is affected by conserved cysteine residues. J Biol Chem 278(29):26757-64 | SGD |
| IEA: Inferred from Electronic Annotation with EBI:IPR002113 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro | |
| IEA: Inferred from Electronic Annotation with EBI:KW-0999 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| IEA: Inferred from Electronic Annotation with EBI:SL-0168 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| AAC3/YBR085W | ISA: Inferred from Sequence Alignment with SGD:AAC1, SGD:PET9 Assigned on 2008-04-16 |
manually curated | Kolarov J, et al. (1990) A third ADP/ATP translocator gene in yeast. J Biol Chem 265(21):12711-6 | SGD |
| IEA: Inferred from Electronic Annotation with EBI:IPR002113 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro | |
| IEA: Inferred from Electronic Annotation with EBI:KW-0999 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| IEA: Inferred from Electronic Annotation with EBI:SL-0168 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| ADK2/YER170W | IDA: Inferred from Direct Assay Assigned on 2002-09-27 |
manually curated | Schricker R, et al. (1995) Strain-dependent occurrence of functional GTP:AMP phosphotransferase (AK3) in Saccharomyces cerevisiae. J Biol Chem 270(52):31103-10 | SGD |
| IDA: Inferred from Direct Assay Assigned on 2005-03-14 |
manually curated | Gu Y, et al. (2005) A GTP:AMP phosphotransferase, Adk2p, in Saccharomyces cerevisiae. Role of the C terminus in protein folding/stabilization, thermal tolerance, and enzymatic activity. J Biol Chem 280(19):18604-9 | SGD | |
| AEP3/YPL005W | IDA: Inferred from Direct Assay Assigned on 2004-04-27 |
manually curated | Ellis TP, et al. (2004) Aep3p stabilizes the mitochondrial bicistronic mRNA encoding subunits 6 and 8 of the H+-translocating ATP synthase of Saccharomyces cerevisiae. J Biol Chem 279(16):15728-33 | SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0999 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| IEA: Inferred from Electronic Annotation with EBI:SL-0168 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| AFG1/YEL052W | IDA: Inferred from Direct Assay Assigned on 2007-06-08 |
manually curated | Khalimonchuk O, et al. (2007) Evidence for a pro-oxidant intermediate in the assembly of cytochrome oxidase. J Biol Chem 282(24):17442-9 | SGD |
| AFG3/YER017C | IDA: Inferred from Direct Assay Assigned on 2001-01-18 |
manually curated | Tauer R, et al. (1994) Yta10p, a member of a novel ATPase family in yeast, is essential for mitochondrial function. FEBS Lett 353(2):197-200 | SGD |
| AGC1/YPR021C | ISS: Inferred from Sequence or structural Similarity with SGD:PET9 Assigned on 2007-06-20 |
manually curated | Belenkiy R, et al. (2000) The yeast mitochondrial transport proteins: new sequences and consensus residues, lack of direct relation between consensus residues and transmembrane helices, expression patterns of the transport protein genes, and protein-protein interactions with other proteins. Biochim Biophys Acta 1467(1):207-18 | SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0999 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| IEA: Inferred from Electronic Annotation with EBI:SL-0168 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| AIM13/YFR011C | IEA: Inferred from Electronic Annotation with EBI:KW-0999 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0168 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| AIM37/YNL100W | IEA: Inferred from Electronic Annotation with EBI:KW-0999 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0168 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| AIM5/YBR262C | IEA: Inferred from Electronic Annotation with EBI:KW-0999 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0168 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| ARH1/YDR376W | IDA: Inferred from Direct Assay Assigned on 2002-08-20 |
manually curated | Lacour T, et al. (1998) Characterization of recombinant adrenodoxin reductase homologue (Arh1p) from yeast. Implication in in vitro cytochrome p45011beta monooxygenase system. J Biol Chem 273(37):23984-92 | SGD |
| ATM1/YMR301C | IDA: Inferred from Direct Assay Assigned on 2001-01-18 |
manually curated | Leighton J and Schatz G (1995) An ABC transporter in the mitochondrial inner membrane is required for normal growth of yeast. EMBO J 14(1):188-95 | SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0999 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| IEA: Inferred from Electronic Annotation with EBI:SL-0168 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| ATP1/YBL099W | IEA: Inferred from Electronic Annotation with EBI:KW-0999 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0168 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| ATP10/YLR393W | IPI: Inferred from Physical Interaction with SGD:ATP6 Assigned on 2008-02-04 |
manually curated | Tzagoloff A, et al. (2004) Atp10p assists assembly of Atp6p into the F0 unit of the yeast mitochondrial ATPase. J Biol Chem 279(19):19775-80 | SGD |
| IEA: Inferred from Electronic Annotation with EBI:IPR007849 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro | |
| IEA: Inferred from Electronic Annotation with EBI:KW-0999 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| IEA: Inferred from Electronic Annotation with EBI:SL-0168 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| ATP14/YLR295C | IEA: Inferred from Electronic Annotation with EBI:KW-0999 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0168 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| ATP15/YPL271W | IEA: Inferred from Electronic Annotation with EBI:KW-0999 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0168 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| ATP16/YDL004W | IEA: Inferred from Electronic Annotation with EBI:KW-0999 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0168 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| ATP17/YDR377W | IEA: Inferred from Electronic Annotation with EBI:KW-0999 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0168 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| ATP19/YOL077W-A | IEA: Inferred from Electronic Annotation with EBI:KW-0999 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0168 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| ATP2/YJR121W | IEA: Inferred from Electronic Annotation with EBI:KW-0999 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0168 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| ATP22/YDR350C | IDA: Inferred from Direct Assay Assigned on 2003-06-18 |
manually curated | Helfenbein KG, et al. (2003) ATP22, a nuclear gene required for expression of the F0 sector of mitochondrial ATPase in Saccharomyces cerevisiae. J Biol Chem 278(22):19751-6 | SGD |
| IEA: Inferred from Electronic Annotation with EBI:IPR017207 Last Updated 2013-03-02 |
computational | DDB, et al. (2001) Gene Ontology annotation through association of InterPro records with GO terms. | InterPro | |
| IEA: Inferred from Electronic Annotation with EBI:KW-0999 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| IEA: Inferred from Electronic Annotation with EBI:SL-0168 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| ATP23/YNR020C | IDA: Inferred from Direct Assay Assigned on 2007-02-14 |
manually curated | Zeng X, et al. (2007) The metalloprotease encoded by ATP23 has a dual function in processing and assembly of subunit 6 of mitochondrial ATPase. Mol Biol Cell 18(2):617-26 | SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0999 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| IEA: Inferred from Electronic Annotation with EBI:SL-0168 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| ATP25/YMR098C | IDA: Inferred from Direct Assay Assigned on 2008-04-01 |
manually curated | Zeng X, et al. (2008) ATP25, a New Nuclear Gene of Saccharomyces cerevisiae Required for Expression and Assembly of the Atp9p Subunit of Mitochondrial ATPase. Mol Biol Cell 19(4):1366-77 | SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0999 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| IEA: Inferred from Electronic Annotation with EBI:SL-0168 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| ATP3/YBR039W | IEA: Inferred from Electronic Annotation with EBI:KW-0999 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0168 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| ATP4/YPL078C | IEA: Inferred from Electronic Annotation with EBI:KW-0999 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0168 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| ATP5/YDR298C | IEA: Inferred from Electronic Annotation with EBI:KW-0999 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0168 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| ATP6/Q0085 | IEA: Inferred from Electronic Annotation with EBI:KW-0999 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0168 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| ATP7/YKL016C | IEA: Inferred from Electronic Annotation with EBI:KW-0999 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0168 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| BCS1/YDR375C | IDA: Inferred from Direct Assay Assigned on 2001-01-18 |
manually curated | Folsch H, et al. (1996) Internal targeting signal of the BCS1 protein: a novel mechanism of import into mitochondria. EMBO J 15(3):479-87 | SGD |
| IEA: Inferred from Electronic Annotation with EBI:KW-0999 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| IEA: Inferred from Electronic Annotation with EBI:SL-0168 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. | UniProtKB | |
| BI2/Q0110 | IEA: Inferred from Electronic Annotation with EBI:KW-0999 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on manual assignment of UniProtKB keywords in UniProtKB/Swiss-Prot entries. | UniProtKB |
| IEA: Inferred from Electronic Annotation with EBI:SL-0168 Last Updated 2013-03-02 |
computational | UniProt-GOA (2011) Gene Ontology annotation based on the manual assignment of UniProtKB Subcellular Location terms in UniProtKB/Swiss-Prot entries. | UniProtKB | |



