Ontology: Cellular Component (GO:0005742)

Definition: A large complex of the mitochondrial outer membrane that mediates transport of proteins into all mitochondrial compartments.

Synonyms: GIP complex; TOM complex

View Ontology: (graph) | (text)

This table lists the methods used to annotate genes either directly to the term mitochondrial outer membrane translocase complex (8 genes) or to its variants containing one or more qualifiers (0 genes). Note that some genes may have been annotated by more than one method so the numbers in the table below may not add up to the totals given here.

Annotation Method	GO Term	# Yeast Genes Annotated
Manually curated (download data)	mitochondrial outer membrane translocase complex	8
High-throughput	none	none
Computational (download data)	mitochondrial outer membrane translocase complex	3

Links to Additional Annotations:

• View annotations in multiple organisms using
• Search for S. cerevisiae genes annotated, by the Manually curated or High-throughput methods, to this term or to any terms that are descended from this term, i.e., child terms representing more specific biology than this term.

Annotation details for genes that have been directly annotated to the term mitochondrial outer membrane translocase complex or its variants containing one or more qualifiers (NOT, contributes to, or colocalizes with).

mitochondrial outer membrane translocase complex      8 genes directly annotated to this term
Locus	Evidence	Annotation Method	Reference	Assigned By
MIA40/YKL195W	IDA: Inferred from Direct Assay Assigned on 2006-10-31	manually curated	Terziyska N, et al.  (2005) Mia40, a novel factor for protein import into the intermembrane space of mitochondria is able to bind metal ions. FEBS Lett 579(1):179-84	SGD
TOM20/YGR082W	IDA: Inferred from Direct Assay Assigned on 2009-04-09	manually curated	Dekker PJ, et al.  (1998) Preprotein translocase of the outer mitochondrial membrane: molecular dissection and assembly of the general import pore complex. Mol Cell Biol 18(11):6515-24	SGD
	IEA: Inferred from Electronic Annotation with EBI:IPR002056 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
TOM22/YNL131W	IDA: Inferred from Direct Assay Assigned on 2009-04-09	manually curated	Dekker PJ, et al.  (1998) Preprotein translocase of the outer mitochondrial membrane: molecular dissection and assembly of the general import pore complex. Mol Cell Biol 18(11):6515-24	SGD
TOM40/YMR203W	IDA: Inferred from Direct Assay Assigned on 2009-04-07	manually curated	Dekker PJ, et al.  (1998) Preprotein translocase of the outer mitochondrial membrane: molecular dissection and assembly of the general import pore complex. Mol Cell Biol 18(11):6515-24	SGD
TOM5/YPR133W-A	IDA: Inferred from Direct Assay Assigned on 2009-04-10	manually curated	Dietmeier K, et al.  (1997) Tom5 functionally links mitochondrial preprotein receptors to the general import pore. Nature 388(6638):195-200	SGD
TOM6/YOR045W	IMP: Inferred from Mutant Phenotype Assigned on 2009-04-10	manually curated	Dekker PJ, et al.  (1998) Preprotein translocase of the outer mitochondrial membrane: molecular dissection and assembly of the general import pore complex. Mol Cell Biol 18(11):6515-24	SGD
	IMP: Inferred from Mutant Phenotype Assigned on 2001-01-18	manually curated	Alconada A, et al.  (1995) The mitochondrial receptor complex: the small subunit Mom8b/Isp6 supports association of receptors with the general insertion pore and transfer of preproteins. Mol Cell Biol 15(11):6196-205	SGD
	IEA: Inferred from Electronic Annotation with EBI:IPR020266 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
TOM7/YNL070W	IDA: Inferred from Direct Assay Assigned on 2009-04-10	manually curated	Dekker PJ, et al.  (1998) Preprotein translocase of the outer mitochondrial membrane: molecular dissection and assembly of the general import pore complex. Mol Cell Biol 18(11):6515-24	SGD
	IMP: Inferred from Mutant Phenotype Assigned on 2001-01-18	manually curated	Honlinger A, et al.  (1996) Tom7 modulates the dynamics of the mitochondrial outer membrane translocase and plays a pathway-related role in protein import. EMBO J 15(9):2125-37	SGD
	IEA: Inferred from Electronic Annotation with EBI:IPR012621 Last Updated 2013-03-02	computational	DDB, et al.  (2001) Gene Ontology annotation through association of InterPro records with GO terms.	InterPro
TOM70/YNL121C	IDA: Inferred from Direct Assay Assigned on 2009-04-03	manually curated	Dekker PJ, et al.  (1998) Preprotein translocase of the outer mitochondrial membrane: molecular dissection and assembly of the general import pore complex. Mol Cell Biol 18(11):6515-24	SGD

SGD Home About Blog Site Map Help Terms of Use
© Stanford University, Stanford, CA 94305.